estradiol-5960 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the estradiol-5960 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOX3 acyl-CoA oxidase 3, pristanoyl
AGMAT agmatine ureohydrolase (agmatinase)
AK5 adenylate kinase 5
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALK anaplastic lymphoma receptor tyrosine kinase
AMPH amphiphysin
ATP11A ATPase, class VI, type 11A
BAIAP3 BAI1-associated protein 3
BICD1 bicaudal D homolog 1 (Drosophila)
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CALHM2 calcium homeostasis modulator 2
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCDC7 coiled-coil domain containing 7
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDK18 cyclin-dependent kinase 18
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CIZ1 CDKN1A interacting zinc finger protein 1
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
DRD2 dopamine receptor D2
DVL2 dishevelled segment polarity protein 2
ELSPBP1 epididymal sperm binding protein 1
EPS8L1 EPS8-like 1
EXD3 exonuclease 3'-5' domain containing 3
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GAS2 growth arrest-specific 2
GCKR glucokinase (hexokinase 4) regulator
GLS2 glutaminase 2 (liver, mitochondrial)
GNRHR gonadotropin-releasing hormone receptor
GPR161 G protein-coupled receptor 161
GTF2I general transcription factor IIi
HEATR6 HEAT repeat containing 6
HKDC1 hexokinase domain containing 1
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HOOK1 hook microtubule-tethering protein 1
HOXC13 homeobox C13
IDUA iduronidase, alpha-L-
IL11RA interleukin 11 receptor, alpha
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KDM8 lysine (K)-specific demethylase 8
KLHL11 kelch-like family member 11
KLK10 kallikrein-related peptidase 10
KRT32 keratin 32, type I
KRT37 keratin 37, type I
LINC00652 long intergenic non-protein coding RNA 652
LIPG lipase, endothelial
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MEGF9 multiple EGF-like-domains 9
MLH3 mutL homolog 3
MOCS1 molybdenum cofactor synthesis 1
MPPE1 metallophosphoesterase 1
MST1 macrophage stimulating 1
MUC6 mucin 6, oligomeric mucus/gel-forming
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NAAA N-acylethanolamine acid amidase
NEO1 neogenin 1
NEUROD1 neuronal differentiation 1
NF1 neurofibromin 1
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NPIPB15 nuclear pore complex interacting protein family, member B15
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PADI2 peptidyl arginine deiminase, type II
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRDM5 PR domain containing 5
RAP1GAP RAP1 GTPase activating protein
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RBM12B RNA binding motif protein 12B
REC8 REC8 meiotic recombination protein
RGS10 regulator of G-protein signaling 10
RUNX1 runt-related transcription factor 1
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SGSM3 small G protein signaling modulator 3
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SPN sialophorin
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SSBP1 single-stranded DNA binding protein 1, mitochondrial
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STX7 syntaxin 7
TAOK1 TAO kinase 1
TINAGL1 tubulointerstitial nephritis antigen-like 1
TM2D1 TM2 domain containing 1
TMPRSS2 transmembrane protease, serine 2
TNK2 tyrosine kinase, non-receptor, 2
TRIM3 tripartite motif containing 3
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TSNAXIP1 translin-associated factor X interacting protein 1
TTLL1 tubulin tyrosine ligase-like family member 1
TXK TXK tyrosine kinase
UBE3B ubiquitin protein ligase E3B
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
ZEB1 zinc finger E-box binding homeobox 1
ZER1 zyg-11 related, cell cycle regulator
ZHX3 zinc fingers and homeoboxes 3
ZNF614 zinc finger protein 614

decreased expression

Symbol Name
ADAP2 ArfGAP with dual PH domains 2
AIRE autoimmune regulator
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANP32A-IT1 ANP32A intronic transcript 1
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATAD5 ATPase family, AAA domain containing 5
ATAT1 alpha tubulin acetyltransferase 1
CCNT1 cyclin T1
CEP112 centrosomal protein 112kDa
CES3 carboxylesterase 3
CLDN14 claudin 14
CPZ carboxypeptidase Z
CSF1R colony stimulating factor 1 receptor
CSN3 casein kappa
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1
CTNNBL1 catenin, beta like 1
DEPDC5 DEP domain containing 5
DIO3 deiodinase, iodothyronine, type III
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EPN1 epsin 1
FBXO2 F-box protein 2
FGF22 fibroblast growth factor 22
GADD45G growth arrest and DNA-damage-inducible, gamma
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPALPP1 GPALPP motifs containing 1
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HESX1 HESX homeobox 1
HINFP histone H4 transcription factor
HIST1H3G histone cluster 1, H3g
HIST1H4D histone cluster 1, H4d
HLX H2.0-like homeobox
HOXB9 homeobox B9
INCENP inner centromere protein antigens 135/155kDa
IPO8 importin 8
KIFC3 kinesin family member C3
KLF2 Kruppel-like factor 2
KLF3 Kruppel-like factor 3 (basic)
KLHL29 kelch-like family member 29
L2HGDH L-2-hydroxyglutarate dehydrogenase
LMTK1 lemur tail kinase 1
LOC100127972 uncharacterized LOC100127972
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRP3 low density lipoprotein receptor-related protein 3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAGEF1 melanoma antigen family F1
MEGF6 multiple EGF-like-domains 6
METTL16 methyltransferase like 16
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MTG1 mitochondrial ribosome-associated GTPase 1
MUC3B mucin 3B, cell surface associated
NCS1 neuronal calcium sensor 1
NDNF neuron-derived neurotrophic factor
NIPAL2 NIPA-like domain containing 2
NRTN neurturin
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
POLL polymerase (DNA directed), lambda
PTPRH protein tyrosine phosphatase, receptor type, H
RAB3A RAB3A, member RAS oncogene family
RFPL3 ret finger protein-like 3
RGS19 regulator of G-protein signaling 19
RNF126P1 ring finger protein 126 pseudogene 1
RPGRIP1L RPGRIP1-like
RUNDC3B RUN domain containing 3B
SCGB2A2 secretoglobin, family 2A, member 2
SCML2 sex comb on midleg-like 2 (Drosophila)
SCN2A sodium channel, voltage gated, type II alpha subunit
SEPP1 selenoprotein P, plasma, 1
SGK2 serum/glucocorticoid regulated kinase 2
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
STEAP4 STEAP family member 4
SYNGR3 synaptogyrin 3
TCEAL2 transcription elongation factor A (SII)-like 2
THOP1 thimet oligopeptidase 1
TLX3 T-cell leukemia homeobox 3
TMSB15A thymosin beta 15a
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
UBQLN4 ubiquilin 4
UGT8 UDP glycosyltransferase 8
ULBP2 UL16 binding protein 2
WDR18 WD repeat domain 18
WNT16 wingless-type MMTV integration site family, member 16
ZBTB48 zinc finger and BTB domain containing 48
ZNF197 zinc finger protein 197
ZNF214 zinc finger protein 214
ZNF668 zinc finger protein 668
ZNF675 zinc finger protein 675
ZNF711 zinc finger protein 711
ZNF749 zinc finger protein 749
ZNF76 zinc finger protein 76