| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the estradiol-6200 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTN2 | actinin, alpha 2 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| AGFG2 | ArfGAP with FG repeats 2 |
| AHI1 | Abelson helper integration site 1 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ALDOB | aldolase B, fructose-bisphosphate |
| ALOX5 | arachidonate 5-lipoxygenase |
| AQP9 | aquaporin 9 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| BCL9 | B-cell CLL/lymphoma 9 |
| BIN1 | bridging integrator 1 |
| BMP7 | bone morphogenetic protein 7 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| C1ORF68 | chromosome 1 open reading frame 68 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CDC14B | cell division cycle 14B |
| CDK10 | cyclin-dependent kinase 10 |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CLEC4A | C-type lectin domain family 4, member A |
| COL1A1 | collagen, type I, alpha 1 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DDR1 | discoidin domain receptor tyrosine kinase 1 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DPEP2 | dipeptidase 2 |
| DPP4 | dipeptidyl-peptidase 4 |
| EHD1 | EH-domain containing 1 |
| EPS8L1 | EPS8-like 1 |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FCN3 | ficolin (collagen/fibrinogen domain containing) 3 |
| GGA3 | golgi-associated, gamma adaptin ear containing, ARF binding protein 3 |
| GM2A | GM2 ganglioside activator |
| GPR153 | G protein-coupled receptor 153 |
| GPX2 | glutathione peroxidase 2 |
| HHLA1 | HERV-H LTR-associating 1 |
| HIC2 | hypermethylated in cancer 2 |
| HPD | 4-hydroxyphenylpyruvate dioxygenase |
| IGL | immunoglobulin lambda locus |
| IL5RA | interleukin 5 receptor, alpha |
| INHBA | inhibin, beta A |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
| KDM4B | lysine (K)-specific demethylase 4B |
| KHK | ketohexokinase (fructokinase) |
| KLHL36 | kelch-like family member 36 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| LMF1 | lipase maturation factor 1 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MASP1 | mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) |
| MCPH1 | microcephalin 1 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase |
| MIOS | missing oocyte, meiosis regulator, homolog (Drosophila) |
| MSRB2 | methionine sulfoxide reductase B2 |
| MUC3B | mucin 3B, cell surface associated |
| MUC8 | mucin 8 |
| NCAN | neurocan |
| NCOR2 | nuclear receptor corepressor 2 |
| NIPAL2 | NIPA-like domain containing 2 |
| NOP16 | NOP16 nucleolar protein |
| NPTX1 | neuronal pentraxin I |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| PCBP3 | poly(rC) binding protein 3 |
| PDE11A | phosphodiesterase 11A |
| PDLIM5 | PDZ and LIM domain 5 |
| PER3 | period circadian clock 3 |
| PGLYRP1 | peptidoglycan recognition protein 1 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLIN2 | perilipin 2 |
| PLXDC1 | plexin domain containing 1 |
| PON1 | paraoxonase 1 |
| PVR | poliovirus receptor |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAB3D | RAB3D, member RAS oncogene family |
| RAB6B | RAB6B, member RAS oncogene family |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 |
| SIN3B | SIN3 transcription regulator family member B |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SP100 | SP100 nuclear antigen |
| SSPN | sarcospan |
| ST7L | suppression of tumorigenicity 7 like |
| TFF2 | trefoil factor 2 |
| THBS1 | thrombospondin 1 |
| TMEM53 | transmembrane protein 53 |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| TP63 | tumor protein p63 |
| TPM3 | tropomyosin 3 |
| TRIM3 | tripartite motif containing 3 |
| TRPM8 | transient receptor potential cation channel, subfamily M, member 8 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AICDA | activation-induced cytidine deaminase |
| AIM2 | absent in melanoma 2 |
| AMDHD2 | amidohydrolase domain containing 2 |
| BCAR3 | breast cancer anti-estrogen resistance 3 |
| BCAS3 | breast carcinoma amplified sequence 3 |
| BMP15 | bone morphogenetic protein 15 |
| BZRAP1 | benzodiazepine receptor (peripheral) associated protein 1 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| C4ORF19 | chromosome 4 open reading frame 19 |
| CAPN5 | calpain 5 |
| CCDC71 | coiled-coil domain containing 71 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CD1C | CD1c molecule |
| CDK3 | cyclin-dependent kinase 3 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CNTN1 | contactin 1 |
| COLEC12 | collectin sub-family member 12 |
| COPG2IT1 | COPG2 imprinted transcript 1 (non-protein coding) |
| CPTP | ceramide-1-phosphate transfer protein |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CRY2 | cryptochrome circadian clock 2 |
| CUX2 | cut-like homeobox 2 |
| DDN | dendrin |
| DEAF1 | DEAF1 transcription factor |
| DFNA5 | deafness, autosomal dominant 5 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DPY19L2P2 | DPY19L2 pseudogene 2 |
| DSPP | dentin sialophosphoprotein |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| ERCC6 | excision repair cross-complementation group 6 |
| EXO5 | exonuclease 5 |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FBXO22 | F-box protein 22 |
| FRMD1 | FERM domain containing 1 |
| GAA | glucosidase, alpha; acid |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GID4 | GID complex subunit 4 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| HCN4 | hyperpolarization activated cyclic nucleotide gated potassium channel 4 |
| HTRA1 | HtrA serine peptidase 1 |
| IFNA17 | interferon, alpha 17 |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| IL11RA | interleukin 11 receptor, alpha |
| IMPAD1 | inositol monophosphatase domain containing 1 |
| INA | internexin neuronal intermediate filament protein, alpha |
| KIAA1107 | KIAA1107 |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| MMP3 | matrix metallopeptidase 3 |
| NPFFR1 | neuropeptide FF receptor 1 |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| P2RY1 | purinergic receptor P2Y, G-protein coupled, 1 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PHACTR1 | phosphatase and actin regulator 1 |
| PHOX2A | paired-like homeobox 2a |
| PITX2 | paired-like homeodomain 2 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRAF2 | PRA1 domain family, member 2 |
| PRKCE | protein kinase C, epsilon |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| RANBP17 | RAN binding protein 17 |
| RCAN3 | RCAN family member 3 |
| S100A13 | S100 calcium binding protein A13 |
| SAA4 | serum amyloid A4, constitutive |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SEC14L5 | SEC14-like 5 (S. cerevisiae) |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC17A2 | solute carrier family 17, member 2 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SOX21 | SRY (sex determining region Y)-box 21 |
| SP140 | SP140 nuclear body protein |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TAOK1 | TAO kinase 1 |
| TBC1D17 | TBC1 domain family, member 17 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| URGCP | upregulator of cell proliferation |
| USB1 | U6 snRNA biogenesis 1 |
| ZNF205 | zinc finger protein 205 |
| ZNF552 | zinc finger protein 552 |
| ZNF695 | zinc finger protein 695 |
| ZNF816 | zinc finger protein 816 |