| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the estradiol-665 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADGRG1 | adhesion G protein-coupled receptor G1 |
| AEN | apoptosis enhancing nuclease |
| AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 |
| ARPC4 | actin related protein 2/3 complex, subunit 4, 20kDa |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BMP7 | bone morphogenetic protein 7 |
| C16ORF58 | chromosome 16 open reading frame 58 |
| CACTIN | cactin, spliceosome C complex subunit |
| CCHCR1 | coiled-coil alpha-helical rod protein 1 |
| CFD | complement factor D (adipsin) |
| CHERP | calcium homeostasis endoplasmic reticulum protein |
| CLDN11 | claudin 11 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| DDX23 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DENND4C | DENN/MADD domain containing 4C |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DNAJC16 | DnaJ (Hsp40) homolog, subfamily C, member 16 |
| DRP2 | dystrophin related protein 2 |
| DUSP6 | dual specificity phosphatase 6 |
| EDA | ectodysplasin A |
| FAF1 | Fas (TNFRSF6) associated factor 1 |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GBAP1 | glucosidase, beta, acid pseudogene 1 |
| GFOD2 | glucose-fructose oxidoreductase domain containing 2 |
| GLI3 | GLI family zinc finger 3 |
| GLRX3 | glutaredoxin 3 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| H2AFY2 | H2A histone family, member Y2 |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| HRASLS2 | HRAS-like suppressor 2 |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 |
| IL13RA1 | interleukin 13 receptor, alpha 1 |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| KDELC1 | KDEL (Lys-Asp-Glu-Leu) containing 1 |
| KIF3A | kinesin family member 3A |
| KIZ | kizuna centrosomal protein |
| LEMD3 | LEM domain containing 3 |
| LRRN2 | leucine rich repeat neuronal 2 |
| MAN1B1 | mannosidase, alpha, class 1B, member 1 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MED1 | mediator complex subunit 1 |
| METTL2B | methyltransferase like 2B |
| MXD4 | MAX dimerization protein 4 |
| MYL10 | myosin, light chain 10, regulatory |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NOTCH1 | notch 1 |
| NSUN5P1 | NOP2/Sun domain family, member 5 pseudogene 1 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PLSCR3 | phospholipid scramblase 3 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
| PSMD5 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 |
| PTH1R | parathyroid hormone 1 receptor |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RECQL5 | RecQ protein-like 5 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
| RNF141 | ring finger protein 141 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| RUNX3 | runt-related transcription factor 3 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SPATA2 | spermatogenesis associated 2 |
| SPN | sialophorin |
| SPRR1A | small proline-rich protein 1A |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| TCF3 | transcription factor 3 |
| TMEM184B | transmembrane protein 184B |
| TMEM97 | transmembrane protein 97 |
| TOM1L2 | target of myb1-like 2 (chicken) |
| TRIM58 | tripartite motif containing 58 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TTC38 | tetratricopeptide repeat domain 38 |
| VAV2 | vav 2 guanine nucleotide exchange factor |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WDR91 | WD repeat domain 91 |
| WNK1 | WNK lysine deficient protein kinase 1 |
| ZFP36 | ZFP36 ring finger protein |
| ZFX | zinc finger protein, X-linked |
| ZGPAT | zinc finger, CCCH-type with G patch domain |
| ZNF609 | zinc finger protein 609 |
| ZSCAN32 | zinc finger and SCAN domain containing 32 |
| Symbol | Name |
|---|---|
| ABCG4 | ATP-binding cassette, sub-family G (WHITE), member 4 |
| ADCYAP1 | adenylate cyclase activating polypeptide 1 (pituitary) |
| ADORA3 | adenosine A3 receptor |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| APEX2 | APEX nuclease (apurinic/apyrimidinic endonuclease) 2 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase |
| AXIN1 | axin 1 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCNA1 | cyclin A1 |
| CDH18 | cadherin 18, type 2 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CENPC | centromere protein C |
| CHN1 | chimerin 1 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DMBT1 | deleted in malignant brain tumors 1 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| FAM188A | family with sequence similarity 188, member A |
| FAM63A | family with sequence similarity 63, member A |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| GDF9 | growth differentiation factor 9 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GP6 | glycoprotein VI (platelet) |
| GPR27 | G protein-coupled receptor 27 |
| GRB7 | growth factor receptor-bound protein 7 |
| HAND1 | heart and neural crest derivatives expressed 1 |
| HDAC9 | histone deacetylase 9 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase |
| HIST1H3G | histone cluster 1, H3g |
| HOXC11 | homeobox C11 |
| IGFLR1 | IGF-like family receptor 1 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| KLHL25 | kelch-like family member 25 |
| KLHL28 | kelch-like family member 28 |
| KLHL3 | kelch-like family member 3 |
| KLK8 | kallikrein-related peptidase 8 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LOC730101 | uncharacterized LOC730101 |
| LRRC15 | leucine rich repeat containing 15 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MED23 | mediator complex subunit 23 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| NABP2 | nucleic acid binding protein 2 |
| NELL2 | NEL-like 2 (chicken) |
| NPY | neuropeptide Y |
| OGFRL1 | opioid growth factor receptor-like 1 |
| OTUD3 | OTU deubiquitinase 3 |
| OVOL1 | ovo-like zinc finger 1 |
| PC | pyruvate carboxylase |
| PDCD1 | programmed cell death 1 |
| PER3 | period circadian clock 3 |
| PGC | progastricsin (pepsinogen C) |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
| PRR16 | proline rich 16 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 |
| PTBP2 | polypyrimidine tract binding protein 2 |
| PTGFR | prostaglandin F receptor (FP) |
| RASL11B | RAS-like, family 11, member B |
| RPL23AP7 | ribosomal protein L23a pseudogene 7 |
| S100A12 | S100 calcium binding protein A12 |
| SETD1B | SET domain containing 1B |
| SHROOM2 | shroom family member 2 |
| SIX1 | SIX homeobox 1 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SLC35F6 | solute carrier family 35, member F6 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
| SPON2 | spondin 2, extracellular matrix protein |
| STRA6 | stimulated by retinoic acid 6 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TG | thyroglobulin |
| TMEM8A | transmembrane protein 8A |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UBXN8 | UBX domain protein 8 |
| USP6 | ubiquitin specific peptidase 6 |
| VWA1 | von Willebrand factor A domain containing 1 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF408 | zinc finger protein 408 |
| ZNF432 | zinc finger protein 432 |
| ZNF557 | zinc finger protein 557 |
| ZNF671 | zinc finger protein 671 |
| ZNF83 | zinc finger protein 83 |