estradiol-6718 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the estradiol-6718 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
ADGRB2 adhesion G protein-coupled receptor B2
ALPI alkaline phosphatase, intestinal
APC adenomatous polyposis coli
ARHGAP26 Rho GTPase activating protein 26
ARHGAP44 Rho GTPase activating protein 44
ATF7IP activating transcription factor 7 interacting protein
BCAM basal cell adhesion molecule (Lutheran blood group)
BMPR1B bone morphogenetic protein receptor, type IB
C7ORF26 chromosome 7 open reading frame 26
C8A complement component 8, alpha polypeptide
C9ORF156 chromosome 9 open reading frame 156
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CLDN17 claudin 17
CNGB3 cyclic nucleotide gated channel beta 3
COPE coatomer protein complex, subunit epsilon
CTNND2 catenin (cadherin-associated protein), delta 2
DCLK2 doublecortin-like kinase 2
DIO3 deiodinase, iodothyronine, type III
DPT dermatopontin
DSG1 desmoglein 1
EDA ectodysplasin A
ENPEP glutamyl aminopeptidase (aminopeptidase A)
EPS8L1 EPS8-like 1
FABP3 fatty acid binding protein 3, muscle and heart
FABP7 fatty acid binding protein 7, brain
FILIP1L filamin A interacting protein 1-like
GAS7 growth arrest-specific 7
GPR75 G protein-coupled receptor 75
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HSPB6 heat shock protein, alpha-crystallin-related, B6
IFNA8 interferon, alpha 8
IGHD immunoglobulin heavy constant delta
KIDINS220 kinase D-interacting substrate, 220kDa
KLHL35 kelch-like family member 35
LAMC3 laminin, gamma 3
LEFTY2 left-right determination factor 2
LENEP lens epithelial protein
LMOD1 leiomodin 1 (smooth muscle)
MAU2 MAU2 sister chromatid cohesion factor
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MORC1 MORC family CW-type zinc finger 1
MSX2 msh homeobox 2
MTCP1 mature T-cell proliferation 1
MTMR7 myotubularin related protein 7
MVB12B multivesicular body subunit 12B
MYO7A myosin VIIA
N4BP1 NEDD4 binding protein 1
NCR2 natural cytotoxicity triggering receptor 2
NOTCH4 notch 4
NR5A2 nuclear receptor subfamily 5, group A, member 2
OMD osteomodulin
OR12D3 olfactory receptor, family 12, subfamily D, member 3
PAPPA2 pappalysin 2
PARD6A par-6 family cell polarity regulator alpha
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PDIA2 protein disulfide isomerase family A, member 2
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLA2G3 phospholipase A2, group III
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLSCR2 phospholipid scramblase 2
POU4F1 POU class 4 homeobox 1
POU5F1B POU class 5 homeobox 1B
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRKCA protein kinase C, alpha
PTEN phosphatase and tensin homolog
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RAB6B RAB6B, member RAS oncogene family
RBM12B-AS1 RBM12B antisense RNA 1
RCE1 Ras converting CAAX endopeptidase 1
REEP1 receptor accessory protein 1
RGS12 regulator of G-protein signaling 12
RHOT2 ras homolog family member T2
RNF122 ring finger protein 122
RPL10 ribosomal protein L10
RPS3A ribosomal protein S3A
SAMD4B sterile alpha motif domain containing 4B
SCN1B sodium channel, voltage gated, type I beta subunit
SEPP1 selenoprotein P, plasma, 1
SETD1A SET domain containing 1A
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SNX13 sorting nexin 13
SOCS3 suppressor of cytokine signaling 3
SORBS2 sorbin and SH3 domain containing 2
SPAG8 sperm associated antigen 8
SPTBN5 spectrin, beta, non-erythrocytic 5
SRRT serrate, RNA effector molecule
TACR1 tachykinin receptor 1
TJP3 tight junction protein 3
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TRIM3 tripartite motif containing 3
TUBA3C tubulin, alpha 3c
TUBB1 tubulin, beta 1 class VI
UPK1B uroplakin 1B
WNT2B wingless-type MMTV integration site family, member 2B
ZC3H7B zinc finger CCCH-type containing 7B

decreased expression

Symbol Name
AARSD1 alanyl-tRNA synthetase domain containing 1
ABHD17B abhydrolase domain containing 17B
AGMAT agmatine ureohydrolase (agmatinase)
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
ARMCX2 armadillo repeat containing, X-linked 2
ATAT1 alpha tubulin acetyltransferase 1
AURKC aurora kinase C
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BATF3 basic leucine zipper transcription factor, ATF-like 3
CASZ1 castor zinc finger 1
CEL carboxyl ester lipase
CENPJ centromere protein J
CHM choroideremia (Rab escort protein 1)
CLDN11 claudin 11
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DBR1 debranching RNA lariats 1
EDIL3 EGF-like repeats and discoidin I-like domains 3
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EML4 echinoderm microtubule associated protein like 4
ETNK2 ethanolamine kinase 2
EXOC5 exocyst complex component 5
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM53B family with sequence similarity 53, member B
FBXL7 F-box and leucine-rich repeat protein 7
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
GPATCH2L G patch domain containing 2-like
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GPNMB glycoprotein (transmembrane) nmb
GPX2 glutathione peroxidase 2
GRAMD1C GRAM domain containing 1C
GRIP2 glutamate receptor interacting protein 2
GRTP1 growth hormone regulated TBC protein 1
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
IFT54 intraflagellar transport 54
IL2 interleukin 2
IL36RN interleukin 36 receptor antagonist
IPO8 importin 8
IRAK4 interleukin-1 receptor-associated kinase 4
KIAA0319L KIAA0319-like
KIAA0753 KIAA0753
KLF2 Kruppel-like factor 2
KPNA5 karyopherin alpha 5 (importin alpha 6)
KRT8P12 keratin 8 pseudogene 12
KRT9 keratin 9, type I
LMAN1 lectin, mannose-binding, 1
MCC mutated in colorectal cancers
MNX1 motor neuron and pancreas homeobox 1
MON1B MON1 secretory trafficking family member B
NDRG4 NDRG family member 4
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
PAIP2B poly(A) binding protein interacting protein 2B
PARP3 poly (ADP-ribose) polymerase family, member 3
PDZK1 PDZ domain containing 1
PLAC8 placenta-specific 8
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POMT2 protein-O-mannosyltransferase 2
PRKX protein kinase, X-linked
PTBP3 polypyrimidine tract binding protein 3
PTK7 protein tyrosine kinase 7 (inactive)
PTPRS protein tyrosine phosphatase, receptor type, S
RAI2 retinoic acid induced 2
RGCC regulator of cell cycle
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RRAGB Ras-related GTP binding B
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SETDB1 SET domain, bifurcated 1
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SMG9 SMG9 nonsense mediated mRNA decay factor
SPRYD7 SPRY domain containing 7
STAC SH3 and cysteine rich domain
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRIM25 tripartite motif containing 25
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSC22D4 TSC22 domain family, member 4
TTC30A tetratricopeptide repeat domain 30A
TUBG2 tubulin, gamma 2
TWISTNB TWIST neighbor
USP19 ubiquitin specific peptidase 19
ZBTB22 zinc finger and BTB domain containing 22
ZBTB33 zinc finger and BTB domain containing 33
ZBTB6 zinc finger and BTB domain containing 6
ZMAT5 zinc finger, matrin-type 5
ZNF137P zinc finger protein 137, pseudogene
ZNF222 zinc finger protein 222
ZNF492 zinc finger protein 492
ZNF510 zinc finger protein 510
ZNF675 zinc finger protein 675
ZNF778 zinc finger protein 778
ZSCAN2 zinc finger and SCAN domain containing 2