estradiol-6928 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the estradiol-6928 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ABHD6 abhydrolase domain containing 6
ACRV1 acrosomal vesicle protein 1
ACSL4 acyl-CoA synthetase long-chain family member 4
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ANP32A-IT1 ANP32A intronic transcript 1
ARMCX4 armadillo repeat containing, X-linked 4
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CC2D1A coiled-coil and C2 domain containing 1A
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDC14A cell division cycle 14A
CDON cell adhesion associated, oncogene regulated
CEP162 centrosomal protein 162kDa
CLSTN2 calsyntenin 2
CLU clusterin
COL8A2 collagen, type VIII, alpha 2
CTAG2 cancer/testis antigen 2
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGR3 early growth response 3
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
ELL2 elongation factor, RNA polymerase II, 2
FAM149A family with sequence similarity 149, member A
FAM169A family with sequence similarity 169, member A
FAM63A family with sequence similarity 63, member A
FCMR Fc fragment of IgM receptor
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGF2 fibroblast growth factor 2 (basic)
FGFR1 fibroblast growth factor receptor 1
FRMPD1 FERM and PDZ domain containing 1
GAB2 GRB2-associated binding protein 2
GLI2 GLI family zinc finger 2
GLI3 GLI family zinc finger 3
GPC4 glypican 4
HESX1 HESX homeobox 1
HLA-DMA major histocompatibility complex, class II, DM alpha
HOXC10 homeobox C10
HPS1 Hermansky-Pudlak syndrome 1
IL1RN interleukin 1 receptor antagonist
INHBE inhibin, beta E
IQCE IQ motif containing E
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIF13B kinesin family member 13B
KRT13 keratin 13, type I
KRT15 keratin 15, type I
LOX lysyl oxidase
LRRC41 leucine rich repeat containing 41
MED1 mediator complex subunit 1
NLE1 notchless homolog 1 (Drosophila)
NNAT neuronatin
NPR3 natriuretic peptide receptor 3
NRF1 nuclear respiratory factor 1
OGFR opioid growth factor receptor
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSGIN1 oxidative stress induced growth inhibitor 1
OVGP1 oviductal glycoprotein 1, 120kDa
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PCDHB17P protocadherin beta 17 pseudogene
PDE4A phosphodiesterase 4A, cAMP-specific
PEX10 peroxisomal biogenesis factor 10
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
POLQ polymerase (DNA directed), theta
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PSEN2 presenilin 2
PTN pleiotrophin
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRF protein tyrosine phosphatase, receptor type, F
RHO rhodopsin
RREB1 ras responsive element binding protein 1
SCN1B sodium channel, voltage gated, type I beta subunit
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SGCE sarcoglycan, epsilon
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC12A8 solute carrier family 12, member 8
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SPON1 spondin 1, extracellular matrix protein
SUN2 Sad1 and UNC84 domain containing 2
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
TMEM257 transmembrane protein 257
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNNT3 troponin T type 3 (skeletal, fast)
TRAF3IP3 TRAF3 interacting protein 3
TSNAXIP1 translin-associated factor X interacting protein 1
UNC119 unc-119 homolog (C. elegans)
USP2 ubiquitin specific peptidase 2
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
ZNF770 zinc finger protein 770
ZSCAN12 zinc finger and SCAN domain containing 12

decreased expression

Symbol Name
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANXA1 annexin A1
ATG7 autophagy related 7
BBC3 BCL2 binding component 3
C4ORF29 chromosome 4 open reading frame 29
CAMTA2 calmodulin binding transcription activator 2
CASD1 CAS1 domain containing 1
CCNT1 cyclin T1
CDKL3 cyclin-dependent kinase-like 3
CLK1 CDC-like kinase 1
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COCH cochlin
COQ6 coenzyme Q6 monooxygenase
DHRS3 dehydrogenase/reductase (SDR family) member 3
ECH1 enoyl CoA hydratase 1, peroxisomal
ECSIT ECSIT signalling integrator
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
EFNA1 ephrin-A1
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOC2 exocyst complex component 2
FASTKD5 FAST kinase domains 5
FBRS fibrosin
FICD FIC domain containing
FIP1L1 factor interacting with PAPOLA and CPSF1
GADD45A growth arrest and DNA-damage-inducible, alpha
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPATCH1 G patch domain containing 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HS1BP3 HCLS1 binding protein 3
IFT22 intraflagellar transport 22
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KCNK15 potassium channel, two pore domain subfamily K, member 15
KIAA0753 KIAA0753
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LHFPL2 lipoma HMGIC fusion partner-like 2
LINS lines homolog (Drosophila)
LMBR1L limb development membrane protein 1-like
LOC100287590 uncharacterized LOC100287590
LOC642236 FSHD region gene 1 pseudogene
LY6D lymphocyte antigen 6 complex, locus D
MAST3 microtubule associated serine/threonine kinase 3
MBOAT2 membrane bound O-acyltransferase domain containing 2
METTL2B methyltransferase like 2B
MON1B MON1 secretory trafficking family member B
MORC3 MORC family CW-type zinc finger 3
MT1H metallothionein 1H
MTCL1 microtubule crosslinking factor 1
MXD3 MAX dimerization protein 3
NACA2 nascent polypeptide-associated complex alpha subunit 2
NCAM2 neural cell adhesion molecule 2
NDRG1 N-myc downstream regulated 1
NECAB3 N-terminal EF-hand calcium binding protein 3
NR1H2 nuclear receptor subfamily 1, group H, member 2
OTUD3 OTU deubiquitinase 3
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PDZRN3 PDZ domain containing ring finger 3
PER3 period circadian clock 3
PODXL2 podocalyxin-like 2
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBL1 retinoblastoma-like 1
RNF121 ring finger protein 121
RPH3AL rabphilin 3A-like (without C2 domains)
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SESN1 sestrin 1
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SNIP1 Smad nuclear interacting protein 1
SNX16 sorting nexin 16
SOAT1 sterol O-acyltransferase 1
SOX12 SRY (sex determining region Y)-box 12
SPINK4 serine peptidase inhibitor, Kazal type 4
STAG3 stromal antigen 3
STAP2 signal transducing adaptor family member 2
STARD5 StAR-related lipid transfer (START) domain containing 5
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TBC1D17 TBC1 domain family, member 17
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TGS1 trimethylguanosine synthase 1
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
UROS uroporphyrinogen III synthase
USP18 ubiquitin specific peptidase 18
USP6NL USP6 N-terminal like
VGF VGF nerve growth factor inducible
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZNF767P zinc finger family member 767, pseudogene