| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the estradiol-6968 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ANKRD36 | ankyrin repeat domain 36 |
| ATP11B | ATPase, class VI, type 11B |
| B9D1 | B9 protein domain 1 |
| BCAN | brevican |
| BMP1 | bone morphogenetic protein 1 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCDC121 | coiled-coil domain containing 121 |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CLEC3B | C-type lectin domain family 3, member B |
| CTIF | CBP80/20-dependent translation initiation factor |
| DESI2 | desumoylating isopeptidase 2 |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| DSCAM | Down syndrome cell adhesion molecule |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| DVL2 | dishevelled segment polarity protein 2 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EGR3 | early growth response 3 |
| EMP1 | epithelial membrane protein 1 |
| EPOR | erythropoietin receptor |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FGFR4 | fibroblast growth factor receptor 4 |
| FHL1 | four and a half LIM domains 1 |
| FNDC3A | fibronectin type III domain containing 3A |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GOLGA8A | golgin A8 family, member A |
| GPR87 | G protein-coupled receptor 87 |
| GTDC1 | glycosyltransferase-like domain containing 1 |
| GYG2 | glycogenin 2 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H4F | histone cluster 1, H4f |
| HLA-E | major histocompatibility complex, class I, E |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IFT54 | intraflagellar transport 54 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IL27RA | interleukin 27 receptor, alpha |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| KIAA1109 | KIAA1109 |
| LMO4 | LIM domain only 4 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAP3K12 | mitogen-activated protein kinase kinase kinase 12 |
| MAPK13 | mitogen-activated protein kinase 13 |
| MBD3 | methyl-CpG binding domain protein 3 |
| MBTD1 | mbt domain containing 1 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MED25 | mediator complex subunit 25 |
| MLX | MLX, MAX dimerization protein |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MRPS12 | mitochondrial ribosomal protein S12 |
| MSL3 | male-specific lethal 3 homolog (Drosophila) |
| NAV2 | neuron navigator 2 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OGFOD2 | 2-oxoglutarate and iron-dependent oxygenase domain containing 2 |
| PDE12 | phosphodiesterase 12 |
| PHF3 | PHD finger protein 3 |
| PIP | prolactin-induced protein |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PPM1F | protein phosphatase, Mg2+/Mn2+ dependent, 1F |
| PRDX2 | peroxiredoxin 2 |
| PRMT7 | protein arginine methyltransferase 7 |
| PTPN2 | protein tyrosine phosphatase, non-receptor type 2 |
| QKI | QKI, KH domain containing, RNA binding |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RNASEH2B | ribonuclease H2, subunit B |
| RPL10L | ribosomal protein L10-like |
| RYR2 | ryanodine receptor 2 (cardiac) |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SMAD1 | SMAD family member 1 |
| SNX13 | sorting nexin 13 |
| TADA2A | transcriptional adaptor 2A |
| TBX19 | T-box 19 |
| TIMELESS | timeless circadian clock |
| TMEM183A | transmembrane protein 183A |
| TOP3A | topoisomerase (DNA) III alpha |
| TPM1 | tropomyosin 1 (alpha) |
| TRH | thyrotropin-releasing hormone |
| TRIM2 | tripartite motif containing 2 |
| TRIM21 | tripartite motif containing 21 |
| TTC33 | tetratricopeptide repeat domain 33 |
| TUBA3C | tubulin, alpha 3c |
| TUBA3D | tubulin, alpha 3d |
| XDH | xanthine dehydrogenase |
| ZHX3 | zinc fingers and homeoboxes 3 |
| Symbol | Name |
|---|---|
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 |
| ABLIM3 | actin binding LIM protein family, member 3 |
| ADAM15 | ADAM metallopeptidase domain 15 |
| AMDHD2 | amidohydrolase domain containing 2 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| ATAD2B | ATPase family, AAA domain containing 2B |
| ATG7 | autophagy related 7 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BEX4 | brain expressed, X-linked 4 |
| BPGM | 2,3-bisphosphoglycerate mutase |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CARD8 | caspase recruitment domain family, member 8 |
| CASKIN2 | CASK interacting protein 2 |
| CBX4 | chromobox homolog 4 |
| CCDC85C | coiled-coil domain containing 85C |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CEP170B | centrosomal protein 170B |
| CHKB | choline kinase beta |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| COCH | cochlin |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CTSK | cathepsin K |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| EVPL | envoplakin |
| FAM63A | family with sequence similarity 63, member A |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FOSL1 | FOS-like antigen 1 |
| FOXK2 | forkhead box K2 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GMIP | GEM interacting protein |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| GTF2IRD1 | GTF2I repeat domain containing 1 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| IGSF1 | immunoglobulin superfamily, member 1 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IMPACT | impact RWD domain protein |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| IRF2 | interferon regulatory factor 2 |
| IRF9 | interferon regulatory factor 9 |
| KAT2A | K(lysine) acetyltransferase 2A |
| LIN7B | lin-7 homolog B (C. elegans) |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LOC100272216 | uncharacterized LOC100272216 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MICALL2 | MICAL-like 2 |
| MPI | mannose phosphate isomerase |
| MTMR12 | myotubularin related protein 12 |
| MXD3 | MAX dimerization protein 3 |
| NDRG4 | NDRG family member 4 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| OTUD3 | OTU deubiquitinase 3 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PPP6R1 | protein phosphatase 6, regulatory subunit 1 |
| PQLC1 | PQ loop repeat containing 1 |
| RAB5B | RAB5B, member RAS oncogene family |
| RANBP17 | RAN binding protein 17 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF31 | ring finger protein 31 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SCAMP4 | secretory carrier membrane protein 4 |
| SCPEP1 | serine carboxypeptidase 1 |
| SH2B3 | SH2B adaptor protein 3 |
| SIL1 | SIL1 nucleotide exchange factor |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SNX15 | sorting nexin 15 |
| SP140L | SP140 nuclear body protein-like |
| SPIDR | scaffolding protein involved in DNA repair |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYT17 | synaptotagmin XVII |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TCTA | T-cell leukemia translocation altered |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TRAF2 | TNF receptor-associated factor 2 |
| TRAF5 | TNF receptor-associated factor 5 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| UBQLN4 | ubiquilin 4 |
| VASH2 | vasohibin 2 |
| WDR60 | WD repeat domain 60 |
| ZCCHC6 | zinc finger, CCHC domain containing 6 |
| ZNF350 | zinc finger protein 350 |
| ZNF574 | zinc finger protein 574 |
| ZNF675 | zinc finger protein 675 |
| ZNF8 | zinc finger protein 8 |
| ZSCAN9 | zinc finger and SCAN domain containing 9 |
