estradiol-782 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the estradiol-782 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
ARF3 ADP-ribosylation factor 3
ARNT aryl hydrocarbon receptor nuclear translocator
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
ATRX alpha thalassemia/mental retardation syndrome X-linked
AXIN1 axin 1
BMP7 bone morphogenetic protein 7
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C11ORF24 chromosome 11 open reading frame 24
CARD9 caspase recruitment domain family, member 9
CDC73 cell division cycle 73
CHAF1B chromatin assembly factor 1, subunit B (p60)
CISD1 CDGSH iron sulfur domain 1
COPS8 COP9 signalosome subunit 8
COX5B cytochrome c oxidase subunit Vb
CPOX coproporphyrinogen oxidase
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYB5R3 cytochrome b5 reductase 3
DHCR24 24-dehydrocholesterol reductase
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DLAT dihydrolipoamide S-acetyltransferase
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10
DUSP3 dual specificity phosphatase 3
EDC3 enhancer of mRNA decapping 3
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EGFR epidermal growth factor receptor
EIF3A eukaryotic translation initiation factor 3, subunit A
ELF4 E74-like factor 4 (ets domain transcription factor)
ENSA endosulfine alpha
EPB41L3 erythrocyte membrane protein band 4.1-like 3
EPRS glutamyl-prolyl-tRNA synthetase
EPS15 epidermal growth factor receptor pathway substrate 15
ETV5 ets variant 5
FAM134A family with sequence similarity 134, member A
FAM89B family with sequence similarity 89, member B
FBXO46 F-box protein 46
FEM1B fem-1 homolog b (C. elegans)
FIP1L1 factor interacting with PAPOLA and CPSF1
FLNB filamin B, beta
GMPPB GDP-mannose pyrophosphorylase B
HMG20B high mobility group 20B
IQGAP1 IQ motif containing GTPase activating protein 1
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
JOSD1 Josephin domain containing 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIDINS220 kinase D-interacting substrate, 220kDa
KLHDC10 kelch domain containing 10
LMNB1 lamin B1
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MBD4 methyl-CpG binding domain protein 4
MCL1 myeloid cell leukemia 1
MED20 mediator complex subunit 20
MGA MGA, MAX dimerization protein
MPPE1 metallophosphoesterase 1
MRPL33 mitochondrial ribosomal protein L33
MYC v-myc avian myelocytomatosis viral oncogene homolog
NBR1 neighbor of BRCA1 gene 1
NDEL1 nudE neurodevelopment protein 1-like 1
NIPBL Nipped-B homolog (Drosophila)
NUP188 nucleoporin 188kDa
PAPOLA poly(A) polymerase alpha
PHF3 PHD finger protein 3
PHIP pleckstrin homology domain interacting protein
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PPME1 protein phosphatase methylesterase 1
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RFC1 replication factor C (activator 1) 1, 145kDa
RPL14 ribosomal protein L14
RPL27A ribosomal protein L27a
RPL38 ribosomal protein L38
RPLP2 ribosomal protein, large, P2
RPS11 ribosomal protein S11
RPS2 ribosomal protein S2
RYK receptor-like tyrosine kinase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEC23IP SEC23 interacting protein
SH2B2 SH2B adaptor protein 2
SLMO2 slowmo homolog 2 (Drosophila)
SNAP23 synaptosomal-associated protein, 23kDa
SNIP1 Smad nuclear interacting protein 1
SPDL1 spindle apparatus coiled-coil protein 1
SPG20 spastic paraplegia 20 (Troyer syndrome)
STYXL1 serine/threonine/tyrosine interacting-like 1
TBC1D5 TBC1 domain family, member 5
TCF3 transcription factor 3
TCTN2 tectonic family member 2
TIPIN TIMELESS interacting protein
TM9SF1 transmembrane 9 superfamily member 1
TMEM168 transmembrane protein 168
USPL1 ubiquitin specific peptidase like 1
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae)
WDR48 WD repeat domain 48
WTAP Wilms tumor 1 associated protein
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3
ZNF200 zinc finger protein 200

decreased expression

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACP6 acid phosphatase 6, lysophosphatidic
ACVR2B activin A receptor, type IIB
APOC4 apolipoprotein C-IV
ARMC6 armadillo repeat containing 6
ASB13 ankyrin repeat and SOCS box containing 13
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATG2A autophagy related 2A
AUNIP aurora kinase A and ninein interacting protein
C12ORF49 chromosome 12 open reading frame 49
CARD8 caspase recruitment domain family, member 8
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CCDC176 coiled-coil domain containing 176
CD5 CD5 molecule
CD83 CD83 molecule
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CEP170B centrosomal protein 170B
CER1 cerberus 1, DAN family BMP antagonist
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CNTD2 cyclin N-terminal domain containing 2
CRTAC1 cartilage acidic protein 1
DDIT3 DNA-damage-inducible transcript 3
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNAAF2 dynein, axonemal, assembly factor 2
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DOCK1 dedicator of cytokinesis 1
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
EGLN1 egl-9 family hypoxia-inducible factor 1
EGLN2 egl-9 family hypoxia-inducible factor 2
FAM46A family with sequence similarity 46, member A
GDI1 GDP dissociation inhibitor 1
GPRC5D G protein-coupled receptor, class C, group 5, member D
GPX2 glutathione peroxidase 2
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
HEBP1 heme binding protein 1
HIST3H2A histone cluster 3, H2a
IFT20 intraflagellar transport 20
INO80D INO80 complex subunit D
LIMD2 LIM domain containing 2
LINC00312 long intergenic non-protein coding RNA 312
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRP3 low density lipoprotein receptor-related protein 3
LSP1 lymphocyte-specific protein 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MPV17 MpV17 mitochondrial inner membrane protein
MYO9A myosin IXA
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NBEAL2 neurobeachin-like 2
NEU1 sialidase 1 (lysosomal sialidase)
NFU1 NFU1 iron-sulfur cluster scaffold
NIP7 NIP7, nucleolar pre-rRNA processing protein
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OTUD3 OTU deubiquitinase 3
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PADI1 peptidyl arginine deiminase, type I
PGC progastricsin (pepsinogen C)
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PMVK phosphomevalonate kinase
POTEKP POTE ankyrin domain family, member K, pseudogene
PPCS phosphopantothenoylcysteine synthetase
PQLC3 PQ loop repeat containing 3
QTRT1 queuine tRNA-ribosyltransferase 1
RABL6 RAB, member RAS oncogene family-like 6
RAD9A RAD9 homolog A (S. pombe)
RAMP3 receptor (G protein-coupled) activity modifying protein 3
RPUSD2 RNA pseudouridylate synthase domain containing 2
S100A9 S100 calcium binding protein A9
SALL2 spalt-like transcription factor 2
SAR1B secretion associated, Ras related GTPase 1B
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC25A40 solute carrier family 25, member 40
SNTA1 syntrophin, alpha 1
SOD3 superoxide dismutase 3, extracellular
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SYT13 synaptotagmin XIII
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
TAOK1 TAO kinase 1
TERT telomerase reverse transcriptase
TET3 tet methylcytosine dioxygenase 3
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia)
TMEM186 transmembrane protein 186
TMEM223 transmembrane protein 223
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TSHB thyroid stimulating hormone, beta
TYK2 tyrosine kinase 2
UBA5 ubiquitin-like modifier activating enzyme 5
WBP2 WW domain binding protein 2
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZNF510 zinc finger protein 510
ZNF8 zinc finger protein 8
ZSCAN9 zinc finger and SCAN domain containing 9