| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the estriol-5866 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AASS | aminoadipate-semialdehyde synthase |
| AKR1C4 | aldo-keto reductase family 1, member C4 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ANGPTL2 | angiopoietin-like 2 |
| ANXA10 | annexin A10 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CD58 | CD58 molecule |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CEP68 | centrosomal protein 68kDa |
| CISH | cytokine inducible SH2-containing protein |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CTIF | CBP80/20-dependent translation initiation factor |
| CTSF | cathepsin F |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| ELMO2 | engulfment and cell motility 2 |
| FAM214B | family with sequence similarity 214, member B |
| FBLN1 | fibulin 1 |
| FBXO22 | F-box protein 22 |
| FGF6 | fibroblast growth factor 6 |
| FLJ11292 | |
| FOXN2 | forkhead box N2 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GLP1R | glucagon-like peptide 1 receptor |
| GLRA1 | glycine receptor, alpha 1 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) |
| GSTA3 | glutathione S-transferase alpha 3 |
| HABP4 | hyaluronan binding protein 4 |
| HDAC6 | histone deacetylase 6 |
| HEXA | hexosaminidase A (alpha polypeptide) |
| HIST1H2BN | histone cluster 1, H2bn |
| HOOK1 | hook microtubule-tethering protein 1 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IFI44L | interferon-induced protein 44-like |
| INADL | InaD-like (Drosophila) |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIF25 | kinesin family member 25 |
| KLHL29 | kelch-like family member 29 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| LMAN1 | lectin, mannose-binding, 1 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
| MAP7 | microtubule-associated protein 7 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MCC | mutated in colorectal cancers |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MPZ | myelin protein zero |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MX1 | MX dynamin-like GTPase 1 |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NCKIPSD | NCK interacting protein with SH3 domain |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PHF7 | PHD finger protein 7 |
| PLCD1 | phospholipase C, delta 1 |
| PLD2 | phospholipase D2 |
| PLD3 | phospholipase D family, member 3 |
| PMS2P2 | postmeiotic segregation increased 2 pseudogene 2 |
| PRKCI | protein kinase C, iota |
| RBM34 | RNA binding motif protein 34 |
| RBM48 | RNA binding motif protein 48 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) |
| RIN3 | Ras and Rab interactor 3 |
| RUNX1 | runt-related transcription factor 1 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SELL | selectin L |
| SH2D3A | SH2 domain containing 3A |
| SLC15A1 | solute carrier family 15 (oligopeptide transporter), member 1 |
| SLC6A2 | solute carrier family 6 (neurotransmitter transporter), member 2 |
| SLCO1A2 | solute carrier organic anion transporter family, member 1A2 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| STAC | SH3 and cysteine rich domain |
| TACC1 | transforming, acidic coiled-coil containing protein 1 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
| TBCD | tubulin folding cofactor D |
| TDRD1 | tudor domain containing 1 |
| TFDP3 | transcription factor Dp family, member 3 |
| THRA | thyroid hormone receptor, alpha |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TP53I11 | tumor protein p53 inducible protein 11 |
| VCAN | versican |
| WEE1 | WEE1 G2 checkpoint kinase |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| YY2 | YY2 transcription factor |
| ZFHX2 | zinc finger homeobox 2 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| AATF | apoptosis antagonizing transcription factor |
| ACP2 | acid phosphatase 2, lysosomal |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| AMPD2 | adenosine monophosphate deaminase 2 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase |
| BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide |
| C16ORF62 | chromosome 16 open reading frame 62 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C4ORF19 | chromosome 4 open reading frame 19 |
| C5 | complement component 5 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CCDC106 | coiled-coil domain containing 106 |
| CCNT1 | cyclin T1 |
| CDK3 | cyclin-dependent kinase 3 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEP85 | centrosomal protein 85kDa |
| CFAP69 | cilia and flagella associated protein 69 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain |
| CRYBA2 | crystallin, beta A2 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DEAF1 | DEAF1 transcription factor |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 |
| ECM1 | extracellular matrix protein 1 |
| FADS2 | fatty acid desaturase 2 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GLT8D2 | glycosyltransferase 8 domain containing 2 |
| GPR137B | G protein-coupled receptor 137B |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H3B | histone cluster 1, H3b |
| HLX | H2.0-like homeobox |
| HYAL2 | hyaluronoglucosaminidase 2 |
| IFNA14 | interferon, alpha 14 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| ITM2C | integral membrane protein 2C |
| JUNB | jun B proto-oncogene |
| KIAA0513 | KIAA0513 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| MAGEF1 | melanoma antigen family F1 |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| METRN | meteorin, glial cell differentiation regulator |
| MGAT4B | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B |
| MYO9A | myosin IXA |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PDGFRL | platelet-derived growth factor receptor-like |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PISD | phosphatidylserine decarboxylase |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PMCH | pro-melanin-concentrating hormone |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PRKCD | protein kinase C, delta |
| RANBP17 | RAN binding protein 17 |
| RPL10L | ribosomal protein L10-like |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SCAI | suppressor of cancer cell invasion |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SOD3 | superoxide dismutase 3, extracellular |
| STX1A | syntaxin 1A (brain) |
| STX5 | syntaxin 5 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| SYNPO | synaptopodin |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TAOK1 | TAO kinase 1 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TOMM22 | translocase of outer mitochondrial membrane 22 homolog (yeast) |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRAIP | TRAF interacting protein |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TUBA3C | tubulin, alpha 3c |
| UNC13B | unc-13 homolog B (C. elegans) |
| URM1 | ubiquitin related modifier 1 |
| UROS | uroporphyrinogen III synthase |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VEZT | vezatin, adherens junctions transmembrane protein |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZNF175 | zinc finger protein 175 |
| ZNF442 | zinc finger protein 442 |
| ZNF551 | zinc finger protein 551 |
| ZNF580 | zinc finger protein 580 |
| ZNF84 | zinc finger protein 84 |
| ZNF862 | zinc finger protein 862 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
