| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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194 genes differentially expressed following the estriol-7220 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| AMACR | alpha-methylacyl-CoA racemase |
| AP4E1 | adaptor-related protein complex 4, epsilon 1 subunit |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ATP10B | ATPase, class V, type 10B |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 |
| BAX | BCL2-associated X protein |
| BTBD7 | BTB (POZ) domain containing 7 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CHM | choroideremia (Rab escort protein 1) |
| CHML | choroideremia-like (Rab escort protein 2) |
| COL14A1 | collagen, type XIV, alpha 1 |
| DCTN1 | dynactin 1 |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| EGR3 | early growth response 3 |
| EPOR | erythropoietin receptor |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 |
| EVI2B | ecotropic viral integration site 2B |
| FCMR | Fc fragment of IgM receptor |
| FRMPD1 | FERM and PDZ domain containing 1 |
| FYB | FYN binding protein |
| FZD10 | frizzled class receptor 10 |
| GABRQ | gamma-aminobutyric acid (GABA) A receptor, theta |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GLIPR1 | GLI pathogenesis-related 1 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits |
| GNRHR | gonadotropin-releasing hormone receptor |
| HFE | hemochromatosis |
| HIST1H1D | histone cluster 1, H1d |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HNF1A | HNF1 homeobox A |
| HRH2 | histamine receptor H2 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| INE1 | inactivation escape 1 (non-protein coding) |
| JAM3 | junctional adhesion molecule 3 |
| KCNIP1 | Kv channel interacting protein 1 |
| KLF12 | Kruppel-like factor 12 |
| KRT19P2 | keratin 19 pseudogene 2 |
| KRT6B | keratin 6B, type II |
| LAPTM5 | lysosomal protein transmembrane 5 |
| LIF | leukemia inhibitory factor |
| LOXL3 | lysyl oxidase-like 3 |
| LRRC8B | leucine rich repeat containing 8 family, member B |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAPK8 | mitogen-activated protein kinase 8 |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MNDA | myeloid cell nuclear differentiation antigen |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MRAS | muscle RAS oncogene homolog |
| MSI1 | musashi RNA-binding protein 1 |
| MUSK | muscle, skeletal, receptor tyrosine kinase |
| NFX1 | nuclear transcription factor, X-box binding 1 |
| NLE1 | notchless homolog 1 (Drosophila) |
| NOX1 | NADPH oxidase 1 |
| OCA2 | oculocutaneous albinism II |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
| PAPPA2 | pappalysin 2 |
| PAX5 | paired box 5 |
| PCM1 | pericentriolar material 1 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PLK4 | polo-like kinase 4 |
| PRF1 | perforin 1 (pore forming protein) |
| PRO2964 | uncharacterized protein PRO2964 |
| PRSS16 | protease, serine, 16 (thymus) |
| PTCRA | pre T-cell antigen receptor alpha |
| PTPRA | protein tyrosine phosphatase, receptor type, A |
| RAB35 | RAB35, member RAS oncogene family |
| RB1 | retinoblastoma 1 |
| RFXAP | regulatory factor X-associated protein |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SERHL2 | serine hydrolase-like 2 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SNX13 | sorting nexin 13 |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| STK3 | serine/threonine kinase 3 |
| SYBU | syntabulin (syntaxin-interacting) |
| TGM2 | transglutaminase 2 |
| TMEM209 | transmembrane protein 209 |
| TMEM212 | transmembrane protein 212 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TOP3A | topoisomerase (DNA) III alpha |
| TRIB2 | tribbles pseudokinase 2 |
| UBE3A | ubiquitin protein ligase E3A |
| UBOX5 | U-box domain containing 5 |
| VNN1 | vanin 1 |
| WSCD1 | WSC domain containing 1 |
| WWOX | WW domain containing oxidoreductase |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZFY | zinc finger protein, Y-linked |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF286A | zinc finger protein 286A |
| ZNF41 | zinc finger protein 41 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ADCY6 | adenylate cyclase 6 |
| ADGRG6 | adhesion G protein-coupled receptor G6 |
| ALPK1 | alpha-kinase 1 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C3ORF52 | chromosome 3 open reading frame 52 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCNT1 | cyclin T1 |
| CD302 | CD302 molecule |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CLSPN | claspin |
| CLSTN1 | calsyntenin 1 |
| COBL | cordon-bleu WH2 repeat protein |
| COL4A5 | collagen, type IV, alpha 5 |
| CRY1 | cryptochrome circadian clock 1 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FHOD1 | formin homology 2 domain containing 1 |
| GAA | glucosidase, alpha; acid |
| GATA6 | GATA binding protein 6 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| H2AFY2 | H2A histone family, member Y2 |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HCFC2 | host cell factor C2 |
| HMHA1 | histocompatibility (minor) HA-1 |
| HOXC13 | homeobox C13 |
| IL4R | interleukin 4 receptor |
| IRX4 | iroquois homeobox 4 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KLHL36 | kelch-like family member 36 |
| LAMA3 | laminin, alpha 3 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 |
| LHX6 | LIM homeobox 6 |
| LOC730101 | uncharacterized LOC730101 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRP6 | low density lipoprotein receptor-related protein 6 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MICALL2 | MICAL-like 2 |
| MOSPD3 | motile sperm domain containing 3 |
| MYLIP | myosin regulatory light chain interacting protein |
| MYO1E | myosin IE |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NCS1 | neuronal calcium sensor 1 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NUPL2 | nucleoporin like 2 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like |
| PRKX | protein kinase, X-linked |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PRSS8 | protease, serine, 8 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RAB5B | RAB5B, member RAS oncogene family |
| RANBP10 | RAN binding protein 10 |
| RBL1 | retinoblastoma-like 1 |
| RBM23 | RNA binding motif protein 23 |
| RECQL4 | RecQ protein-like 4 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| ROM1 | retinal outer segment membrane protein 1 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SUGP1 | SURP and G patch domain containing 1 |
| TBC1D10B | TBC1 domain family, member 10B |
| TCTA | T-cell leukemia translocation altered |
| TDRD1 | tudor domain containing 1 |
| TEP1 | telomerase-associated protein 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM180 | transmembrane protein 180 |
| TRAPPC11 | trafficking protein particle complex 11 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZFHX3 | zinc finger homeobox 3 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF675 | zinc finger protein 675 |