| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the estrone-4993 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSBG1 | acyl-CoA synthetase bubblegum family member 1 |
| AFF1 | AF4/FMR2 family, member 1 |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| ARTN | artemin |
| ATXN3 | ataxin 3 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CA6 | carbonic anhydrase VI |
| CALB2 | calbindin 2 |
| CAPN9 | calpain 9 |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) |
| CNTFR | ciliary neurotrophic factor receptor |
| DAGLA | diacylglycerol lipase, alpha |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| DOK2 | docking protein 2, 56kDa |
| EGR3 | early growth response 3 |
| ELOVL2 | ELOVL fatty acid elongase 2 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FCAR | Fc fragment of IgA receptor |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GFI1 | growth factor independent 1 transcription repressor |
| GJB3 | gap junction protein, beta 3, 31kDa |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HIST1H1T | histone cluster 1, H1t |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IFNA14 | interferon, alpha 14 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IL1B | interleukin 1, beta |
| IL2RB | interleukin 2 receptor, beta |
| ING1 | inhibitor of growth family, member 1 |
| INO80B | INO80 complex subunit B |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| IRS2 | insulin receptor substrate 2 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KIDINS220 | kinase D-interacting substrate, 220kDa |
| KLF12 | Kruppel-like factor 12 |
| LENEP | lens epithelial protein |
| LIF | leukemia inhibitory factor |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LOC100127972 | uncharacterized LOC100127972 |
| LOX | lysyl oxidase |
| LRRC61 | leucine rich repeat containing 61 |
| MAGOH2P | mago-nashi homolog 2, pseudogene |
| MEF2D | myocyte enhancer factor 2D |
| MID1 | midline 1 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NABP1 | nucleic acid binding protein 1 |
| NCKIPSD | NCK interacting protein with SH3 domain |
| NFASC | neurofascin |
| NOP16 | NOP16 nucleolar protein |
| NPPA | natriuretic peptide A |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NXPE4 | neurexophilin and PC-esterase domain family, member 4 |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PCDH17 | protocadherin 17 |
| PEX3 | peroxisomal biogenesis factor 3 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PLEC | plectin |
| PNMAL1 | paraneoplastic Ma antigen family-like 1 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RDH8 | retinol dehydrogenase 8 (all-trans) |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| RUNX1 | runt-related transcription factor 1 |
| RXRB | retinoid X receptor, beta |
| S100A8 | S100 calcium binding protein A8 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SEC14L4 | SEC14-like 4 (S. cerevisiae) |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SLC17A4 | solute carrier family 17, member 4 |
| SLCO1A2 | solute carrier organic anion transporter family, member 1A2 |
| STATH | statherin |
| SUPT20H | suppressor of Ty 20 homolog (S. cerevisiae) |
| TLR5 | toll-like receptor 5 |
| TMEM53 | transmembrane protein 53 |
| TNS1 | tensin 1 |
| TOP3B | topoisomerase (DNA) III beta |
| TRIM15 | tripartite motif containing 15 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 |
| VHL | von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase |
| VPS9D1 | VPS9 domain containing 1 |
| WSCD1 | WSC domain containing 1 |
| XAF1 | XIAP associated factor 1 |
| XIST | X inactive specific transcript (non-protein coding) |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| XYLB | xylulokinase homolog (H. influenzae) |
| YIPF4 | Yip1 domain family, member 4 |
| ZNF549 | zinc finger protein 549 |
| ZSCAN12 | zinc finger and SCAN domain containing 12 |
| Symbol | Name |
|---|---|
| ABHD14A | abhydrolase domain containing 14A |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A |
| ANXA1 | annexin A1 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| C11ORF73 | chromosome 11 open reading frame 73 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CDK3 | cyclin-dependent kinase 3 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLDN9 | claudin 9 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| EFCAB2 | EF-hand calcium binding domain 2 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| FAM169A | family with sequence similarity 169, member A |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FKBP5 | FK506 binding protein 5 |
| FRK | fyn-related Src family tyrosine kinase |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPATCH2L | G patch domain containing 2-like |
| GTF2I | general transcription factor IIi |
| H2AFY2 | H2A histone family, member Y2 |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase |
| HIST1H2BI | histone cluster 1, H2bi |
| ICK | intestinal cell (MAK-like) kinase |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| INO80D | INO80 complex subunit D |
| IPO8 | importin 8 |
| IRF6 | interferon regulatory factor 6 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MDK | midkine (neurite growth-promoting factor 2) |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MORC3 | MORC family CW-type zinc finger 3 |
| MXRA7 | matrix-remodelling associated 7 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PLA2G10 | phospholipase A2, group X |
| PLD3 | phospholipase D family, member 3 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPAP2C | phosphatidic acid phosphatase type 2C |
| PROS1 | protein S (alpha) |
| PTK6 | protein tyrosine kinase 6 |
| PVRL3 | poliovirus receptor-related 3 |
| RAB5B | RAB5B, member RAS oncogene family |
| RFTN1 | raftlin, lipid raft linker 1 |
| RPGRIP1L | RPGRIP1-like |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SKIL | SKI-like proto-oncogene |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SNAI2 | snail family zinc finger 2 |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| STX1A | syntaxin 1A (brain) |
| TBL3 | transducin (beta)-like 3 |
| TCEAL1 | transcription elongation factor A (SII)-like 1 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMC5 | transmembrane channel-like 5 |
| TMSB15A | thymosin beta 15a |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRAPPC6A | trafficking protein particle complex 6A |
| TRPS1 | trichorhinophalangeal syndrome I |
| TSPO | translocator protein (18kDa) |
| UNKL | unkempt family zinc finger-like |
| VGF | VGF nerve growth factor inducible |
| VWA1 | von Willebrand factor A domain containing 1 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZIC1 | Zic family member 1 |
| ZNF226 | zinc finger protein 226 |
| ZNF286A | zinc finger protein 286A |
