| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the estrone-6448 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD2 | abhydrolase domain containing 2 |
| ACRV1 | acrosomal vesicle protein 1 |
| ADCK2 | aarF domain containing kinase 2 |
| ADH7 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
| ADORA1 | adenosine A1 receptor |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C4BPA | complement component 4 binding protein, alpha |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CAV3 | caveolin 3 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CD82 | CD82 molecule |
| CD8A | CD8a molecule |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CHRND | cholinergic receptor, nicotinic, delta (muscle) |
| CHST4 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLUL1 | clusterin-like 1 (retinal) |
| CSNK1G1 | casein kinase 1, gamma 1 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| DCAF11 | DDB1 and CUL4 associated factor 11 |
| DESI2 | desumoylating isopeptidase 2 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DNASE1L3 | deoxyribonuclease I-like 3 |
| DPP4 | dipeptidyl-peptidase 4 |
| EGR3 | early growth response 3 |
| EML2 | echinoderm microtubule associated protein like 2 |
| EPHB1 | EPH receptor B1 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| FAM120C | family with sequence similarity 120C |
| FAM182B | family with sequence similarity 182, member B |
| FAM46C | family with sequence similarity 46, member C |
| FCAR | Fc fragment of IgA receptor |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FRMD4B | FERM domain containing 4B |
| GLRA1 | glycine receptor, alpha 1 |
| GSPT1 | G1 to S phase transition 1 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HIST1H2BL | histone cluster 1, H2bl |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL1RN | interleukin 1 receptor antagonist |
| IRF4 | interferon regulatory factor 4 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KIF25 | kinesin family member 25 |
| KRT75 | keratin 75, type II |
| LINC00472 | long intergenic non-protein coding RNA 472 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MAPT | microtubule-associated protein tau |
| MAS1 | MAS1 proto-oncogene, G protein-coupled receptor |
| MAX | MYC associated factor X |
| MEFV | Mediterranean fever |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NF1 | neurofibromin 1 |
| NLGN4X | neuroligin 4, X-linked |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDLIM5 | PDZ and LIM domain 5 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLA2G2E | phospholipase A2, group IIE |
| PLCL2 | phospholipase C-like 2 |
| PML | promyelocytic leukemia |
| POPDC3 | popeye domain containing 3 |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PSMD5 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 |
| PSMD9 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PTPRM | protein tyrosine phosphatase, receptor type, M |
| QKI | QKI, KH domain containing, RNA binding |
| RNF6 | ring finger protein (C3H2C3 type) 6 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SERPINI2 | serpin peptidase inhibitor, clade I (pancpin), member 2 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SGSM3 | small G protein signaling modulator 3 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SPON1 | spondin 1, extracellular matrix protein |
| SPTLC1 | serine palmitoyltransferase, long chain base subunit 1 |
| SQLE | squalene epoxidase |
| SSTR4 | somatostatin receptor 4 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TRD | T cell receptor delta locus |
| TRIM2 | tripartite motif containing 2 |
| TRIM29 | tripartite motif containing 29 |
| TUBA4B | tubulin, alpha 4b |
| WHSC1 | Wolf-Hirschhorn syndrome candidate 1 |
| ZHX3 | zinc fingers and homeoboxes 3 |
| ZNF551 | zinc finger protein 551 |
| Symbol | Name |
|---|---|
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ALOX15 | arachidonate 15-lipoxygenase |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARMC6 | armadillo repeat containing 6 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BMP15 | bone morphogenetic protein 15 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD83 | CD83 molecule |
| CFAP44 | cilia and flagella associated protein 44 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CLDN17 | claudin 17 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DEAF1 | DEAF1 transcription factor |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| EFNA1 | ephrin-A1 |
| EPHA4 | EPH receptor A4 |
| FAM186A | family with sequence similarity 186, member A |
| FBXO2 | F-box protein 2 |
| FGL1 | fibrinogen-like 1 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| HYI | hydroxypyruvate isomerase (putative) |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| INO80D | INO80 complex subunit D |
| IPO8 | importin 8 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| IRF6 | interferon regulatory factor 6 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KLHL36 | kelch-like family member 36 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| KRT13 | keratin 13, type I |
| LHX1 | LIM homeobox 1 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
| MXD3 | MAX dimerization protein 3 |
| MYO1E | myosin IE |
| MYO1F | myosin IF |
| NIPAL2 | NIPA-like domain containing 2 |
| NPR3 | natriuretic peptide receptor 3 |
| NRSN2 | neurensin 2 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| PADI1 | peptidyl arginine deiminase, type I |
| PER3 | period circadian clock 3 |
| PLD3 | phospholipase D family, member 3 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PMF1 | polyamine-modulated factor 1 |
| PODNL1 | podocan-like 1 |
| PODXL2 | podocalyxin-like 2 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRDM14 | PR domain containing 14 |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PROL1 | proline rich, lacrimal 1 |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAPSN | receptor-associated protein of the synapse |
| RCAN3 | RCAN family member 3 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SECTM1 | secreted and transmembrane 1 |
| SFRP5 | secreted frizzled-related protein 5 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| TBC1D2 | TBC1 domain family, member 2 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| THBS3 | thrombospondin 3 |
| TMC5 | transmembrane channel-like 5 |
| TMEM121 | transmembrane protein 121 |
| TOM1 | target of myb1 (chicken) |
| TPCN1 | two pore segment channel 1 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRAIP | TRAF interacting protein |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| UBQLN4 | ubiquilin 4 |
| UBTD1 | ubiquitin domain containing 1 |
| VGF | VGF nerve growth factor inducible |
| VIM | vimentin |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF205 | zinc finger protein 205 |
