| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the estrone-6647 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ADAMTS8 | ADAM metallopeptidase with thrombospondin type 1 motif, 8 |
| AIF1 | allograft inflammatory factor 1 |
| AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 |
| AKAP11 | A kinase (PRKA) anchor protein 11 |
| AKAP6 | A kinase (PRKA) anchor protein 6 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ALOX5 | arachidonate 5-lipoxygenase |
| ARSA | arylsulfatase A |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATM | ATM serine/threonine kinase |
| B3GAT1 | beta-1,3-glucuronyltransferase 1 |
| BGN | biglycan |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CCR4 | chemokine (C-C motif) receptor 4 |
| CEP295 | centrosomal protein 295kDa |
| CERS4 | ceramide synthase 4 |
| CFAP45 | cilia and flagella associated protein 45 |
| CFDP1 | craniofacial development protein 1 |
| CIC | capicua transcriptional repressor |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) |
| DCT | dopachrome tautomerase |
| DPY19L1 | dpy-19-like 1 (C. elegans) |
| DSCAM | Down syndrome cell adhesion molecule |
| EPX | eosinophil peroxidase |
| ESR1 | estrogen receptor 1 |
| ETV1 | ets variant 1 |
| FGF6 | fibroblast growth factor 6 |
| FLT1 | fms-related tyrosine kinase 1 |
| FRZB | frizzled-related protein |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| HDAC6 | histone deacetylase 6 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| HIF3A | hypoxia inducible factor 3, alpha subunit |
| HIST1H4B | histone cluster 1, H4b |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HOXB6 | homeobox B6 |
| HRASLS2 | HRAS-like suppressor 2 |
| ICAM1 | intercellular adhesion molecule 1 |
| KCNH4 | potassium channel, voltage gated eag related subfamily H, member 4 |
| KIAA1024 | KIAA1024 |
| KLHL22 | kelch-like family member 22 |
| LAMA4 | laminin, alpha 4 |
| LPL | lipoprotein lipase |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MOB3B | MOB kinase activator 3B |
| N4BP1 | NEDD4 binding protein 1 |
| NEK1 | NIMA-related kinase 1 |
| NEU3 | sialidase 3 (membrane sialidase) |
| NGDN | neuroguidin, EIF4E binding protein |
| NPAS1 | neuronal PAS domain protein 1 |
| OLFM1 | olfactomedin 1 |
| OR12D3 | olfactory receptor, family 12, subfamily D, member 3 |
| OTOR | otoraplin |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PEX5L | peroxisomal biogenesis factor 5-like |
| POFUT1 | protein O-fucosyltransferase 1 |
| PON1 | paraoxonase 1 |
| POU1F1 | POU class 1 homeobox 1 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| RHCE | Rh blood group, CcEe antigens |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| SEC14L4 | SEC14-like 4 (S. cerevisiae) |
| SH2D3A | SH2 domain containing 3A |
| SIRT4 | sirtuin 4 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SPATA6 | spermatogenesis associated 6 |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| STC1 | stanniocalcin 1 |
| SULT1E1 | sulfotransferase family 1E, estrogen-preferring, member 1 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TAS2R1 | taste receptor, type 2, member 1 |
| TMEM63A | transmembrane protein 63A |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 |
| TPM1 | tropomyosin 1 (alpha) |
| TRPM3 | transient receptor potential cation channel, subfamily M, member 3 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 |
| UHRF1BP1L | UHRF1 binding protein 1-like |
| UPK2 | uroplakin 2 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| YIPF4 | Yip1 domain family, member 4 |
| ZNF208 | zinc finger protein 208 |
| ZNF24 | zinc finger protein 24 |
| ZNF652 | zinc finger protein 652 |
| Symbol | Name |
|---|---|
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ALPK1 | alpha-kinase 1 |
| ANXA2P1 | annexin A2 pseudogene 1 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BAX | BCL2-associated X protein |
| BBC3 | BCL2 binding component 3 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| C1RL | complement component 1, r subcomponent-like |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD70 | CD70 molecule |
| CLDN14 | claudin 14 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNPY3 | canopy FGF signaling regulator 3 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| CYP39A1 | cytochrome P450, family 39, subfamily A, polypeptide 1 |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| EDAR | ectodysplasin A receptor |
| EGLN2 | egl-9 family hypoxia-inducible factor 2 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EMD | emerin |
| FAM120C | family with sequence similarity 120C |
| FAT4 | FAT atypical cadherin 4 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| FUZ | fuzzy planar cell polarity protein |
| GRAMD4 | GRAM domain containing 4 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HAMP | hepcidin antimicrobial peptide |
| HDAC11 | histone deacetylase 11 |
| HHLA3 | HERV-H LTR-associating 3 |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2AK | histone cluster 1, H2ak |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H4E | histone cluster 1, H4e |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HOXC10 | homeobox C10 |
| HSF2BP | heat shock transcription factor 2 binding protein |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL7R | interleukin 7 receptor |
| KIAA0754 | KIAA0754 |
| LMNB1 | lamin B1 |
| LOC257152 | uncharacterized LOC257152 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MN1 | meningioma (disrupted in balanced translocation) 1 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| OLFML3 | olfactomedin-like 3 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PDE12 | phosphodiesterase 12 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PEX26 | peroxisomal biogenesis factor 26 |
| PLA1A | phospholipase A1 member A |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
| PTK6 | protein tyrosine kinase 6 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SCN8A | sodium channel, voltage gated, type VIII alpha subunit |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SIRT6 | sirtuin 6 |
| SLC12A8 | solute carrier family 12, member 8 |
| SPIDR | scaffolding protein involved in DNA repair |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TAGLN | transgelin |
| TCTN2 | tectonic family member 2 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM121 | transmembrane protein 121 |
| TMEM212 | transmembrane protein 212 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TUBA4B | tubulin, alpha 4b |
| UNC119 | unc-119 homolog (C. elegans) |
| VGF | VGF nerve growth factor inducible |
| WDR18 | WD repeat domain 18 |
| WDR37 | WD repeat domain 37 |
| ZNF214 | zinc finger protein 214 |
| ZNF480 | zinc finger protein 480 |
| ZNF675 | zinc finger protein 675 |
| ZNF711 | zinc finger protein 711 |
| ZW10 | zw10 kinetochore protein |
