estropipate-4472 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the estropipate-4472 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOX3 acyl-CoA oxidase 3, pristanoyl
AFAP1 actin filament associated protein 1
AKAP11 A kinase (PRKA) anchor protein 11
ANKLE2 ankyrin repeat and LEM domain containing 2
ANP32A-IT1 ANP32A intronic transcript 1
APAF1 apoptotic peptidase activating factor 1
ARL2BP ADP-ribosylation factor-like 2 binding protein
ATM ATM serine/threonine kinase
AURKA aurora kinase A
BAAT bile acid CoA:amino acid N-acyltransferase
BEST2 bestrophin 2
BMP7 bone morphogenetic protein 7
BMP8B bone morphogenetic protein 8b
C10ORF12 chromosome 10 open reading frame 12
CCDC132 coiled-coil domain containing 132
CD6 CD6 molecule
CEP152 centrosomal protein 152kDa
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLEC11A C-type lectin domain family 11, member A
CLTCL1 clathrin, heavy chain-like 1
COL3A1 collagen, type III, alpha 1
CSF1 colony stimulating factor 1 (macrophage)
DHRS7 dehydrogenase/reductase (SDR family) member 7
DPF1 D4, zinc and double PHD fingers family 1
DSTYK dual serine/threonine and tyrosine protein kinase
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1
EIF5B eukaryotic translation initiation factor 5B
ELL elongation factor RNA polymerase II
ETV1 ets variant 1
FGF12 fibroblast growth factor 12
FGFR4 fibroblast growth factor receptor 4
FKRP fukutin related protein
FLOT1 flotillin 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GALR3 galanin receptor 3
GLB1L galactosidase, beta 1-like
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GPATCH4 G patch domain containing 4
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
HCRP1 hepatocellular carcinoma-related HCRP1
HDGFRP3 hepatoma-derived growth factor, related protein 3
HEMK1 HemK methyltransferase family member 1
HOMER3 homer scaffolding protein 3
HUS1 HUS1 checkpoint homolog (S. pombe)
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IFT122 intraflagellar transport 122
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCTD17 potassium channel tetramerization domain containing 17
KIAA0319L KIAA0319-like
KMT2A lysine (K)-specific methyltransferase 2A
LINC00312 long intergenic non-protein coding RNA 312
MAP2K5 mitogen-activated protein kinase kinase 5
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MTCP1 mature T-cell proliferation 1
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
NCKAP1 NCK-associated protein 1
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NSUN6 NOP2/Sun domain family, member 6
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1
PCDHGC3 protocadherin gamma subfamily C, 3
PGK1 phosphoglycerate kinase 1
PLK3 polo-like kinase 3
PMCH pro-melanin-concentrating hormone
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PRKCE protein kinase C, epsilon
PRRC2C proline-rich coiled-coil 2C
RAB40AL RAB40A, member RAS oncogene family-like
RAD51B RAD51 paralog B
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RECQL5 RecQ protein-like 5
REL v-rel avian reticuloendotheliosis viral oncogene homolog
REPS1 RALBP1 associated Eps domain containing 1
RETN resistin
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPAIN RPA interacting protein
RPL35A ribosomal protein L35a
RPLP2 ribosomal protein, large, P2
SAP30 Sin3A-associated protein, 30kDa
SBNO1 strawberry notch homolog 1 (Drosophila)
SPRR1B small proline-rich protein 1B
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TEP1 telomerase-associated protein 1
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TLN2 talin 2
TLR2 toll-like receptor 2
TSC2 tuberous sclerosis 2
TXN thioredoxin
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VDAC3 voltage-dependent anion channel 3
WNT16 wingless-type MMTV integration site family, member 16
YIPF4 Yip1 domain family, member 4
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF652 zinc finger protein 652
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ARRB2 arrestin, beta 2
AXIN1 axin 1
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BTBD18 BTB (POZ) domain containing 18
C16ORF59 chromosome 16 open reading frame 59
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CASZ1 castor zinc finger 1
CCDC85C coiled-coil domain containing 85C
CCL27 chemokine (C-C motif) ligand 27
CD101 CD101 molecule
CDHR2 cadherin-related family member 2
CFAP69 cilia and flagella associated protein 69
CHM choroideremia (Rab escort protein 1)
CINP cyclin-dependent kinase 2 interacting protein
CORT cortistatin
CRYGC crystallin, gamma C
CSF1R colony stimulating factor 1 receptor
CTSO cathepsin O
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DDN dendrin
EGLN3 egl-9 family hypoxia-inducible factor 3
ELMO3 engulfment and cell motility 3
EXD3 exonuclease 3'-5' domain containing 3
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GAL3ST4 galactose-3-O-sulfotransferase 4
GMPR guanosine monophosphate reductase
GPATCH2 G patch domain containing 2
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HAMP hepcidin antimicrobial peptide
HDAC11 histone deacetylase 11
HIST1H1D histone cluster 1, H1d
HIST1H3G histone cluster 1, H3g
HIST1H4C histone cluster 1, H4c
HLA-DMA major histocompatibility complex, class II, DM alpha
HOXA6 homeobox A6
HOXC8 homeobox C8
IFI6 interferon, alpha-inducible protein 6
INO80D INO80 complex subunit D
KIRREL kin of IRRE like (Drosophila)
LDHC lactate dehydrogenase C
LINC00260 long intergenic non-protein coding RNA 260
LMTK1 lemur tail kinase 1
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
MAGOHB mago-nashi homolog B (Drosophila)
MANBA mannosidase, beta A, lysosomal
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MCTP2 multiple C2 domains, transmembrane 2
MGP matrix Gla protein
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MRPL44 mitochondrial ribosomal protein L44
MTA2 metastasis associated 1 family, member 2
MXRA8 matrix-remodelling associated 8
NEK11 NIMA-related kinase 11
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NOL10 nucleolar protein 10
NPIPB15 nuclear pore complex interacting protein family, member B15
NUP62CL nucleoporin 62kDa C-terminal like
ODF2 outer dense fiber of sperm tails 2
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PDE8B phosphodiesterase 8B
PHEX phosphate regulating endopeptidase homolog, X-linked
PLA2G1B phospholipase A2, group IB (pancreas)
PLEKHS1 pleckstrin homology domain containing, family S member 1
PRB3 proline-rich protein BstNI subfamily 3
PSD4 pleckstrin and Sec7 domain containing 4
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RNF122 ring finger protein 122
RNF126P1 ring finger protein 126 pseudogene 1
RNF2 ring finger protein 2
RPGRIP1L RPGRIP1-like
RPL23AP32 ribosomal protein L23a pseudogene 32
SLC12A9 solute carrier family 12, member 9
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SMAD7 SMAD family member 7
SMR3A submaxillary gland androgen regulated protein 3A
SPRYD7 SPRY domain containing 7
STON1 stonin 1
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SYNGR3 synaptogyrin 3
SYT17 synaptotagmin XVII
TAOK1 TAO kinase 1
TEX15 testis expressed 15
TIGD6 tigger transposable element derived 6
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TSC22D4 TSC22 domain family, member 4
TSPAN2 tetraspanin 2
TUBA3C tubulin, alpha 3c
USB1 U6 snRNA biogenesis 1
ZBTB48 zinc finger and BTB domain containing 48
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF214 zinc finger protein 214
ZNF480 zinc finger protein 480