estropipate-6808 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the estropipate-6808 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSL4 acyl-CoA synthetase long-chain family member 4
AMH anti-Mullerian hormone
AMPD1 adenosine monophosphate deaminase 1
APOE apolipoprotein E
APOL6 apolipoprotein L, 6
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARTN artemin
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
B9D1 B9 protein domain 1
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
BCL2L2 BCL2-like 2
BTBD2 BTB (POZ) domain containing 2
C10ORF12 chromosome 10 open reading frame 12
C11ORF63 chromosome 11 open reading frame 63
C17ORF53 chromosome 17 open reading frame 53
C19ORF57 chromosome 19 open reading frame 57
C2ORF27A chromosome 2 open reading frame 27A
CAPN15 calpain 15
CDC14A cell division cycle 14A
CES3 carboxylesterase 3
CFAP44 cilia and flagella associated protein 44
CLDN11 claudin 11
CLIC2 chloride intracellular channel 2
CNPY3 canopy FGF signaling regulator 3
CRAT carnitine O-acetyltransferase
CXCL12 chemokine (C-X-C motif) ligand 12
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DOCK6 dedicator of cytokinesis 6
EGR3 early growth response 3
EHBP1L1 EH domain binding protein 1-like 1
ENPEP glutamyl aminopeptidase (aminopeptidase A)
FAM168A family with sequence similarity 168, member A
FBXL7 F-box and leucine-rich repeat protein 7
FLOT1 flotillin 1
GNAS GNAS complex locus
GRK6 G protein-coupled receptor kinase 6
HIST1H3I histone cluster 1, H3i
IGHA1 immunoglobulin heavy constant alpha 1
KAZN kazrin, periplakin interacting protein
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
LIN7A lin-7 homolog A (C. elegans)
LPCAT4 lysophosphatidylcholine acyltransferase 4
MOCS1 molybdenum cofactor synthesis 1
MTA1 metastasis associated 1
MTMR1 myotubularin related protein 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYOZ3 myozenin 3
NAAA N-acylethanolamine acid amidase
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NMRK1 nicotinamide riboside kinase 1
NOTCH4 notch 4
NPY1R neuropeptide Y receptor Y1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
NUP188 nucleoporin 188kDa
NUP210 nucleoporin 210kDa
NUP54 nucleoporin 54kDa
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OSGIN1 oxidative stress induced growth inhibitor 1
PARP8 poly (ADP-ribose) polymerase family, member 8
PDZK1 PDZ domain containing 1
PER3 period circadian clock 3
PILRA paired immunoglobin-like type 2 receptor alpha
PLAC1 placenta-specific 1
PLEK pleckstrin
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRB1 proline-rich protein BstNI subfamily 1
PVR poliovirus receptor
PYCRL pyrroline-5-carboxylate reductase-like
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RBFA ribosome binding factor A (putative)
RET ret proto-oncogene
RPL7 ribosomal protein L7
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
SFXN3 sideroflexin 3
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SNTA1 syntrophin, alpha 1
SOX9 SRY (sex determining region Y)-box 9
SPAG8 sperm associated antigen 8
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRD5A3 steroid 5 alpha-reductase 3
TBL2 transducin (beta)-like 2
TFF2 trefoil factor 2
TGM2 transglutaminase 2
THBS1 thrombospondin 1
TPM2 tropomyosin 2 (beta)
TRIM29 tripartite motif containing 29
TSPAN32 tetraspanin 32
USF2 upstream transcription factor 2, c-fos interacting
XYLB xylulokinase homolog (H. influenzae)
YTHDC1 YTH domain containing 1
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF174 zinc finger protein 174

decreased expression

Symbol Name
ADTRP androgen-dependent TFPI-regulating protein
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALS2CL ALS2 C-terminal like
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASIC3 acid sensing (proton gated) ion channel 3
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BAG4 BCL2-associated athanogene 4
BBC3 BCL2 binding component 3
BMP4 bone morphogenetic protein 4
BTF3P11 basic transcription factor 3 pseudogene 11
C14ORF93 chromosome 14 open reading frame 93
C8ORF60 chromosome 8 open reading frame 60
CAMK1D calcium/calmodulin-dependent protein kinase ID
CCDC71 coiled-coil domain containing 71
CCNO cyclin O
CLIP4 CAP-GLY domain containing linker protein family, member 4
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CPA4 carboxypeptidase A4
CSF1R colony stimulating factor 1 receptor
CST6 cystatin E/M
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DCAF16 DDB1 and CUL4 associated factor 16
DNAL4 dynein, axonemal, light chain 4
DTX4 deltex 4, E3 ubiquitin ligase
EGLN3 egl-9 family hypoxia-inducible factor 3
EPHA4 EPH receptor A4
EXD3 exonuclease 3'-5' domain containing 3
F2R coagulation factor II (thrombin) receptor
FAM110B family with sequence similarity 110, member B
FAM169A family with sequence similarity 169, member A
FBXW12 F-box and WD repeat domain containing 12
GID4 GID complex subunit 4
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GSTTP1 glutathione S-transferase theta pseudogene 1
HIST1H1D histone cluster 1, H1d
HIST1H3B histone cluster 1, H3b
HLA-J major histocompatibility complex, class I, J (pseudogene)
IDI2-AS1 IDI2 antisense RNA 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
INCENP inner centromere protein antigens 135/155kDa
KPNA5 karyopherin alpha 5 (importin alpha 6)
LGALS4 lectin, galactoside-binding, soluble, 4
LOC100286895 cell division cycle 27 homolog pseudogene
LOC729164 hCG1732469
LRP5L low density lipoprotein receptor-related protein 5-like
LTBP2 latent transforming growth factor beta binding protein 2
LZTFL1 leucine zipper transcription factor-like 1
MDM4 MDM4, p53 regulator
NCALD neurocalcin delta
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEK11 NIMA-related kinase 11
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NOL12 nucleolar protein 12
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLA2G3 phospholipase A2, group III
PLTP phospholipid transfer protein
PLXNB3 plexin B3
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRPH peripherin
PRR14L proline rich 14-like
PTK6 protein tyrosine kinase 6
PTPRS protein tyrosine phosphatase, receptor type, S
RAB27B RAB27B, member RAS oncogene family
RELN reelin
RIN1 Ras and Rab interactor 1
RIN2 Ras and Rab interactor 2
RNF122 ring finger protein 122
RPL13P5 ribosomal protein L13 pseudogene 5
S100A9 S100 calcium binding protein A9
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCGB2A2 secretoglobin, family 2A, member 2
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SNX15 sorting nexin 15
STAB2 stabilin 2
STX1A syntaxin 1A (brain)
TCTN2 tectonic family member 2
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEP1 telomerase-associated protein 1
TGFB3 transforming growth factor, beta 3
TMC5 transmembrane channel-like 5
TMEM212 transmembrane protein 212
TRIM66 tripartite motif containing 66
TRPV1 transient receptor potential cation channel, subfamily V, member 1
VAX2 ventral anterior homeobox 2
WDR76 WD repeat domain 76
WFDC2 WAP four-disulfide core domain 2
ZBTB22 zinc finger and BTB domain containing 22
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF205 zinc finger protein 205
ZNF286A zinc finger protein 286A
ZNF480 zinc finger protein 480
ZNF606 zinc finger protein 606
ZNF770 zinc finger protein 770
ZNRD1-AS1 ZNRD1 antisense RNA 1