| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the etacrynic acid-3181 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAMDC | adipogenesis associated, Mth938 domain containing |
| ADAM30 | ADAM metallopeptidase domain 30 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ARTN | artemin |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCDC64 | coiled-coil domain containing 64 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CEP250 | centrosomal protein 250kDa |
| CIB2 | calcium and integrin binding family member 2 |
| CLDN10 | claudin 10 |
| COL10A1 | collagen, type X, alpha 1 |
| CSF1R | colony stimulating factor 1 receptor |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DMRT1 | doublesex and mab-3 related transcription factor 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DUOX1 | dual oxidase 1 |
| EPAS1 | endothelial PAS domain protein 1 |
| EPX | eosinophil peroxidase |
| FAS | Fas cell surface death receptor |
| FOSL1 | FOS-like antigen 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GCLM | glutamate-cysteine ligase, modifier subunit |
| GM2A | GM2 ganglioside activator |
| HCG4 | HLA complex group 4 (non-protein coding) |
| HEG1 | heart development protein with EGF-like domains 1 |
| HEXA-AS1 | HEXA antisense RNA 1 |
| HMOX1 | heme oxygenase 1 |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IKZF4 | IKAROS family zinc finger 4 (Eos) |
| IL23A | interleukin 23, alpha subunit p19 |
| KCND1 | potassium channel, voltage gated Shal related subfamily D, member 1 |
| KLHL1 | kelch-like family member 1 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| KRT37 | keratin 37, type I |
| KRTAP1-3 | keratin associated protein 1-3 |
| LMF2 | lipase maturation factor 2 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MIR22HG | MIR22 host gene |
| MR1 | major histocompatibility complex, class I-related |
| MTMR3 | myotubularin related protein 3 |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NHLH2 | nescient helix loop helix 2 |
| NKG7 | natural killer cell granule protein 7 |
| NMT2 | N-myristoyltransferase 2 |
| NOL10 | nucleolar protein 10 |
| NTN3 | netrin 3 |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| OPRL1 | opiate receptor-like 1 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PAX2 | paired box 2 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCLO | piccolo presynaptic cytomatrix protein |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PPP1R17 | protein phosphatase 1, regulatory subunit 17 |
| PRDM9 | PR domain containing 9 |
| PROC | protein C (inactivator of coagulation factors Va and VIIIa) |
| PTGIR | prostaglandin I2 (prostacyclin) receptor (IP) |
| RECK | reversion-inducing-cysteine-rich protein with kazal motifs |
| RFPL2 | ret finger protein-like 2 |
| RGS20 | regulator of G-protein signaling 20 |
| RPH3A | rabphilin 3A |
| RPL35A | ribosomal protein L35a |
| SCGB1D1 | secretoglobin, family 1D, member 1 |
| SERPINI2 | serpin peptidase inhibitor, clade I (pancpin), member 2 |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SLC25A30 | solute carrier family 25, member 30 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMIM14 | small integral membrane protein 14 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPON1 | spondin 1, extracellular matrix protein |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| STK24 | serine/threonine kinase 24 |
| SYCP1 | synaptonemal complex protein 1 |
| TCF4 | transcription factor 4 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TRIM10 | tripartite motif containing 10 |
| TXNRD1 | thioredoxin reductase 1 |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZNF423 | zinc finger protein 423 |
| ZNF440 | zinc finger protein 440 |
| ZNF506 | zinc finger protein 506 |
| ZNF814 | zinc finger protein 814 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ADCY6 | adenylate cyclase 6 |
| AFAP1 | actin filament associated protein 1 |
| ALS2CL | ALS2 C-terminal like |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C12ORF4 | chromosome 12 open reading frame 4 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CA11 | carbonic anhydrase XI |
| CCDC85C | coiled-coil domain containing 85C |
| CCP110 | centriolar coiled coil protein 110kDa |
| CEP97 | centrosomal protein 97kDa |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DOC2A | double C2-like domains, alpha |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| EFNA3 | ephrin-A3 |
| EMID1 | EMI domain containing 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FANCE | Fanconi anemia, complementation group E |
| FBXO5 | F-box protein 5 |
| FCHO1 | FCH domain only 1 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GLI3 | GLI family zinc finger 3 |
| GRB7 | growth factor receptor-bound protein 7 |
| H2AFJ | H2A histone family, member J |
| HIRA | histone cell cycle regulator |
| HOXC10 | homeobox C10 |
| HOXC5 | homeobox C5 |
| HOXC8 | homeobox C8 |
| HYAL2 | hyaluronoglucosaminidase 2 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIF13A | kinesin family member 13A |
| KIF1C | kinesin family member 1C |
| KRT13 | keratin 13, type I |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LDHB | lactate dehydrogenase B |
| LHX1 | LIM homeobox 1 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LMNB1 | lamin B1 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| LRRC20 | leucine rich repeat containing 20 |
| LYZ | lysozyme |
| MAP1S | microtubule-associated protein 1S |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MGAT1 | mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MXD3 | MAX dimerization protein 3 |
| NDE1 | nudE neurodevelopment protein 1 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PADI2 | peptidyl arginine deiminase, type II |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLA2G10 | phospholipase A2, group X |
| PLEK2 | pleckstrin 2 |
| PODXL2 | podocalyxin-like 2 |
| POLL | polymerase (DNA directed), lambda |
| PRR15L | proline rich 15-like |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RFTN1 | raftlin, lipid raft linker 1 |
| RGS16 | regulator of G-protein signaling 16 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SDC3 | syndecan 3 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SOX3 | SRY (sex determining region Y)-box 3 |
| SRGN | serglycin |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STX1A | syntaxin 1A (brain) |
| TMEM120B | transmembrane protein 120B |
| TRAF2 | TNF receptor-associated factor 2 |
| TRAIP | TRAF interacting protein |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| WDR25 | WD repeat domain 25 |
| ZNF34 | zinc finger protein 34 |
| ZNF675 | zinc finger protein 675 |
| ZNF696 | zinc finger protein 696 |
| ZNF778 | zinc finger protein 778 |
