etamsylate-2915 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the etamsylate-2915 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADD2 adducin 2 (beta)
ALX3 ALX homeobox 3
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ARHGAP26 Rho GTPase activating protein 26
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
BMP8A bone morphogenetic protein 8a
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C14ORF132 chromosome 14 open reading frame 132
C9ORF9 chromosome 9 open reading frame 9
CARD14 caspase recruitment domain family, member 14
CD1E CD1e molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CELA2B chymotrypsin-like elastase family, member 2B
CGA glycoprotein hormones, alpha polypeptide
CLCN4 chloride channel, voltage-sensitive 4
DAPK2 death-associated protein kinase 2
DAPK3 death-associated protein kinase 3
DDR1 discoidin domain receptor tyrosine kinase 1
DMWD dystrophia myotonica, WD repeat containing
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DOCK6 dedicator of cytokinesis 6
ECE1 endothelin converting enzyme 1
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
FGA fibrinogen alpha chain
FN1 fibronectin 1
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
FXYD3 FXYD domain containing ion transport regulator 3
GBP1 guanylate binding protein 1, interferon-inducible
GLP1R glucagon-like peptide 1 receptor
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GSN-AS1 GSN antisense RNA 1
GUK1 guanylate kinase 1
HHLA1 HERV-H LTR-associating 1
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HMOX2 heme oxygenase 2
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
HTR7P1 5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1
HYAL1 hyaluronoglucosaminidase 1
IGFBP6 insulin-like growth factor binding protein 6
IGLV1-44 immunoglobulin lambda variable 1-44
IL17RB interleukin 17 receptor B
IL27RA interleukin 27 receptor, alpha
IL3RA interleukin 3 receptor, alpha (low affinity)
IL9R interleukin 9 receptor
IMPG2 interphotoreceptor matrix proteoglycan 2
INA internexin neuronal intermediate filament protein, alpha
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGB4 integrin, beta 4
KL klotho
LEF1 lymphoid enhancer-binding factor 1
LEPR leptin receptor
LMNA lamin A/C
MED16 mediator complex subunit 16
MLPH melanophilin
MMP13 matrix metallopeptidase 13
MNMIP1 manchette microtubule inner protein 1
MST1 macrophage stimulating 1
NANOG Nanog homeobox
NEU3 sialidase 3 (membrane sialidase)
NPY4R neuropeptide Y receptor Y4
NR6A1 nuclear receptor subfamily 6, group A, member 1
NRF1 nuclear respiratory factor 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OVGP1 oviductal glycoprotein 1, 120kDa
PDCD6 programmed cell death 6
PDE8B phosphodiesterase 8B
PEX3 peroxisomal biogenesis factor 3
PHC3 polyhomeotic homolog 3 (Drosophila)
PLD3 phospholipase D family, member 3
PLK3 polo-like kinase 3
PML promyelocytic leukemia
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRO2964 uncharacterized protein PRO2964
PRX periaxin
PTCRA pre T-cell antigen receptor alpha
PTPRF protein tyrosine phosphatase, receptor type, F
PTPRS protein tyrosine phosphatase, receptor type, S
RAP1GAP2 RAP1 GTPase activating protein 2
RBM12B RNA binding motif protein 12B
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RYR2 ryanodine receptor 2 (cardiac)
SDC1 syndecan 1
SLC12A8 solute carrier family 12, member 8
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
TMEM63A transmembrane protein 63A
WIPI2 WD repeat domain, phosphoinositide interacting 2
ZFP64 ZFP64 zinc finger protein
ZNF34 zinc finger protein 34
ZNF407 zinc finger protein 407
ZNF528 zinc finger protein 528

decreased expression

Symbol Name
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ACSL4 acyl-CoA synthetase long-chain family member 4
ACYP1 acylphosphatase 1, erythrocyte (common) type
AGO4 argonaute RISC catalytic component 4
ANP32A-IT1 ANP32A intronic transcript 1
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
BBS7 Bardet-Biedl syndrome 7
BCOR BCL6 corepressor
BMI1 BMI1 proto-oncogene, polycomb ring finger
BRIX1 BRX1, biogenesis of ribosomes
CAAP1 caspase activity and apoptosis inhibitor 1
CCL4 chemokine (C-C motif) ligand 4
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEP72 centrosomal protein 72kDa
CLCN6 chloride channel, voltage-sensitive 6
CLDND1 claudin domain containing 1
CRTAP cartilage associated protein
CRY1 cryptochrome circadian clock 1
CYB5R1 cytochrome b5 reductase 1
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DNMBP dynamin binding protein
EGR2 early growth response 2
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
ERCC5 excision repair cross-complementation group 5
ETAA1 Ewing tumor-associated antigen 1
EXD2 exonuclease 3'-5' domain containing 2
FADS2 fatty acid desaturase 2
FAM188A family with sequence similarity 188, member A
FANCC Fanconi anemia, complementation group C
GIMAP6 GTPase, IMAP family member 6
GPR137B G protein-coupled receptor 137B
GRAMD1B GRAM domain containing 1B
GRWD1 glutamate-rich WD repeat containing 1
GUSBP3 glucuronidase, beta pseudogene 3
HCAR3 hydroxycarboxylic acid receptor 3
HMGA2 high mobility group AT-hook 2
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
ICK intestinal cell (MAK-like) kinase
ISG15 ISG15 ubiquitin-like modifier
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNK5 potassium channel, two pore domain subfamily K, member 5
KPNA4 karyopherin alpha 4 (importin alpha 3)
LIG4 ligase IV, DNA, ATP-dependent
LNPEP leucyl/cystinyl aminopeptidase
LZTR1 leucine-zipper-like transcription regulator 1
MANEA mannosidase, endo-alpha
MAST3 microtubule associated serine/threonine kinase 3
MBD5 methyl-CpG binding domain protein 5
MICB MHC class I polypeptide-related sequence B
MIS12 MIS12 kinetochore complex component
MPDU1 mannose-P-dolichol utilization defect 1
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NPIPB15 nuclear pore complex interacting protein family, member B15
NRBF2 nuclear receptor binding factor 2
PCOLCE2 procollagen C-endopeptidase enhancer 2
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PLA2G12A phospholipase A2, group XIIA
PLEKHA5 pleckstrin homology domain containing, family A member 5
POLM polymerase (DNA directed), mu
POR P450 (cytochrome) oxidoreductase
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
QPCT glutaminyl-peptide cyclotransferase
RANGAP1 Ran GTPase activating protein 1
RARS arginyl-tRNA synthetase
RHOH ras homolog family member H
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SECISBP2 SECIS binding protein 2
SH3YL1 SH3 and SYLF domain containing 1
SLC38A6 solute carrier family 38, member 6
SNX16 sorting nexin 16
SOAT1 sterol O-acyltransferase 1
SREBF1 sterol regulatory element binding transcription factor 1
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa
TAOK1 TAO kinase 1
TEC tec protein tyrosine kinase
TMEM251 transmembrane protein 251
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRAPPC11 trafficking protein particle complex 11
TRIM36 tripartite motif containing 36
TTC33 tetratricopeptide repeat domain 33
VCPKMT valosin containing protein lysine (K) methyltransferase
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WDR5B WD repeat domain 5B
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3
ZBED1 zinc finger, BED-type containing 1
ZMAT3 zinc finger, matrin-type 3
ZNF184 zinc finger protein 184
ZNF273 zinc finger protein 273
ZNF32 zinc finger protein 32
ZNF529 zinc finger protein 529