etanidazole-2510 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the etanidazole-2510 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACE angiotensin I converting enzyme
ADGB androglobin
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADRA2C adrenoceptor alpha 2C
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BCL9 B-cell CLL/lymphoma 9
BMP8B bone morphogenetic protein 8b
BTF3P11 basic transcription factor 3 pseudogene 11
CALB2 calbindin 2
CDC25C cell division cycle 25C
COL18A1 collagen, type XVIII, alpha 1
CREM cAMP responsive element modulator
CRHR2 corticotropin releasing hormone receptor 2
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DGKG diacylglycerol kinase, gamma 90kDa
DISC1 disrupted in schizophrenia 1
DLC1 DLC1 Rho GTPase activating protein
EFR3B EFR3 homolog B (S. cerevisiae)
FAM174B family with sequence similarity 174, member B
FAM46C family with sequence similarity 46, member C
FAM65A family with sequence similarity 65, member A
FDPS farnesyl diphosphate synthase
FGFR2 fibroblast growth factor receptor 2
FLJ11292
FOXD2 forkhead box D2
GFER growth factor, augmenter of liver regeneration
GLP1R glucagon-like peptide 1 receptor
GMPR guanosine monophosphate reductase
GPC1 glypican 1
GRHL2 grainyhead-like 2 (Drosophila)
GRIP2 glutamate receptor interacting protein 2
GRPR gastrin-releasing peptide receptor
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HAO2 hydroxyacid oxidase 2 (long chain)
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HIST1H2BJ histone cluster 1, H2bj
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IGFBP5 insulin-like growth factor binding protein 5
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KRT17 keratin 17, type I
KRT75 keratin 75, type II
LENEP lens epithelial protein
LINC00302 long intergenic non-protein coding RNA 302
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAPK10 mitogen-activated protein kinase 10
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MTAP methylthioadenosine phosphorylase
MTL5 metallothionein-like 5, testis-specific (tesmin)
MTRF1L mitochondrial translational release factor 1-like
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NCAM1 neural cell adhesion molecule 1
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NPHP1 nephronophthisis 1 (juvenile)
NRG2 neuregulin 2
OTUD4 OTU deubiquitinase 4
PARP12 poly (ADP-ribose) polymerase family, member 12
PBX2 pre-B-cell leukemia homeobox 2
PDE8B phosphodiesterase 8B
PEX16 peroxisomal biogenesis factor 16
POU4F1 POU class 4 homeobox 1
PPP1R3A protein phosphatase 1, regulatory subunit 3A
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRDM9 PR domain containing 9
PRF1 perforin 1 (pore forming protein)
PRKCQ protein kinase C, theta
RAB6A RAB6A, member RAS oncogene family
RERE arginine-glutamic acid dipeptide (RE) repeats
ROM1 retinal outer segment membrane protein 1
RPL18 ribosomal protein L18
RPL23AP32 ribosomal protein L23a pseudogene 32
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SIGLEC8 sialic acid binding Ig-like lectin 8
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
SLIT3 slit homolog 3 (Drosophila)
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SSTR5 somatostatin receptor 5
STS steroid sulfatase (microsomal), isozyme S
TAPT1 transmembrane anterior posterior transformation 1
TAT tyrosine aminotransferase
TGFB1 transforming growth factor, beta 1
THAP10 THAP domain containing 10
THPO thrombopoietin
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRAPPC9 trafficking protein particle complex 9
TRD T cell receptor delta locus
TYMP thymidine phosphorylase
UPK2 uroplakin 2
WNT16 wingless-type MMTV integration site family, member 16
ZNF639 zinc finger protein 639
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADORA3 adenosine A3 receptor
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALS2CL ALS2 C-terminal like
ARG1 arginase 1
ARHGAP11A Rho GTPase activating protein 11A
ARID5A AT rich interactive domain 5A (MRF1-like)
B3GNT1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BAG4 BCL2-associated athanogene 4
BAMBI BMP and activin membrane-bound inhibitor
CBX7 chromobox homolog 7
CCDC106 coiled-coil domain containing 106
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDR2L cerebellar degeneration-related protein 2-like
CECR1 cat eye syndrome chromosome region, candidate 1
CHMP7 charged multivesicular body protein 7
CPNE7 copine VII
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
ECI2 enoyl-CoA delta isomerase 2
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ERAP2 endoplasmic reticulum aminopeptidase 2
ERCC6L excision repair cross-complementation group 6-like
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERN2 endoplasmic reticulum to nucleus signaling 2
ETAA1 Ewing tumor-associated antigen 1
FAM172A family with sequence similarity 172, member A
FAM188A family with sequence similarity 188, member A
FAM63A family with sequence similarity 63, member A
FBXO3 F-box protein 3
FCHSD2 FCH and double SH3 domains 2
FHL3 four and a half LIM domains 3
G6PD glucose-6-phosphate dehydrogenase
GLTP glycolipid transfer protein
GPALPP1 GPALPP motifs containing 1
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
IL18 interleukin 18
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA0319L KIAA0319-like
KIF13B kinesin family member 13B
KRT81 keratin 81, type II
LIN7A lin-7 homolog A (C. elegans)
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRP3 low density lipoprotein receptor-related protein 3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MEGF8 multiple EGF-like-domains 8
METRN meteorin, glial cell differentiation regulator
MOCS3 molybdenum cofactor synthesis 3
MRAS muscle RAS oncogene homolog
MXD3 MAX dimerization protein 3
MYO9A myosin IXA
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NPIPB3 nuclear pore complex interacting protein family, member B3
NTSR1 neurotensin receptor 1 (high affinity)
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDZD7 PDZ domain containing 7
PGP phosphoglycolate phosphatase
PILRB paired immunoglobin-like type 2 receptor beta
PIR pirin (iron-binding nuclear protein)
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLA2G12A phospholipase A2, group XIIA
PNMA1 paraneoplastic Ma antigen 1
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAB33B RAB33B, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RHOBTB2 Rho-related BTB domain containing 2
RSF1 remodeling and spacing factor 1
SCAI suppressor of cancer cell invasion
SCRIB scribbled planar cell polarity protein
SIL1 SIL1 nucleotide exchange factor
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC35E3 solute carrier family 35, member E3
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
STAT5A signal transducer and activator of transcription 5A
STK25 serine/threonine kinase 25
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SV2A synaptic vesicle glycoprotein 2A
TASP1 taspase, threonine aspartase, 1
TBC1D17 TBC1 domain family, member 17
TCTA T-cell leukemia translocation altered
TRAIP TRAF interacting protein
TRIM16 tripartite motif containing 16
TTC26 tetratricopeptide repeat domain 26
TXLNG taxilin gamma
UNC119 unc-119 homolog (C. elegans)
URGCP upregulator of cell proliferation
USB1 U6 snRNA biogenesis 1
WDR46 WD repeat domain 46
XAB2 XPA binding protein 2
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZEB2 zinc finger E-box binding homeobox 2
ZMAT5 zinc finger, matrin-type 5
ZSCAN5A zinc finger and SCAN domain containing 5A