etanidazole-5730 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the etanidazole-5730 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
ADAM8 ADAM metallopeptidase domain 8
ADAMDEC1 ADAM-like, decysin 1
ADGRD2 adhesion G protein-coupled receptor D2
AFF2 AF4/FMR2 family, member 2
AHNAK AHNAK nucleoprotein
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATAD5 ATPase family, AAA domain containing 5
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CD48 CD48 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CD79B CD79b molecule, immunoglobulin-associated beta
CDH13 cadherin 13
CDHR2 cadherin-related family member 2
CDK10 cyclin-dependent kinase 10
CFAP45 cilia and flagella associated protein 45
CLCN7 chloride channel, voltage-sensitive 7
COL9A3 collagen, type IX, alpha 3
COMMD4 COMM domain containing 4
CPT1A carnitine palmitoyltransferase 1A (liver)
CSF1R colony stimulating factor 1 receptor
CSNK1G1 casein kinase 1, gamma 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DRD2 dopamine receptor D2
EGR4 early growth response 4
ENO3 enolase 3 (beta, muscle)
FAM135A family with sequence similarity 135, member A
FAM65B family with sequence similarity 65, member B
FBXO31 F-box protein 31
FGF4 fibroblast growth factor 4
FGFR1 fibroblast growth factor receptor 1
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GALT galactose-1-phosphate uridylyltransferase
GBP2 guanylate binding protein 2, interferon-inducible
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2
GOLGA6A golgin A6 family, member A
GPR15 G protein-coupled receptor 15
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HHLA1 HERV-H LTR-associating 1
HIST1H3E histone cluster 1, H3e
HOXB2 homeobox B2
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HYAL3 hyaluronoglucosaminidase 3
IL2 interleukin 2
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KRT17 keratin 17, type I
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MCOLN3 mucolipin 3
MECOM MDS1 and EVI1 complex locus
MERTK MER proto-oncogene, tyrosine kinase
MIER2 mesoderm induction early response 1, family member 2
MMP25 matrix metallopeptidase 25
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYOT myotilin
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NOVA1 neuro-oncological ventral antigen 1
NPFF neuropeptide FF-amide peptide precursor
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
PCDH12 protocadherin 12
PDE5A phosphodiesterase 5A, cGMP-specific
PLD1 phospholipase D1, phosphatidylcholine-specific
POM121L2 POM121 transmembrane nucleoporin-like 2
PPP5C protein phosphatase 5, catalytic subunit
PRKG2 protein kinase, cGMP-dependent, type II
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPRB protein tyrosine phosphatase, receptor type, B
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RASAL2 RAS protein activator like 2
RBMS2 RNA binding motif, single stranded interacting protein 2
RGS3 regulator of G-protein signaling 3
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
RUNX1 runt-related transcription factor 1
SBNO1 strawberry notch homolog 1 (Drosophila)
SH3BP2 SH3-domain binding protein 2
SHOX2 short stature homeobox 2
SLC26A1 solute carrier family 26 (anion exchanger), member 1
SOCS3 suppressor of cytokine signaling 3
SOX15 SRY (sex determining region Y)-box 15
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
SYT13 synaptotagmin XIII
TBCD tubulin folding cofactor D
TDRD12 tudor domain containing 12
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TGFA transforming growth factor, alpha
TIMELESS timeless circadian clock
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
UBXN1 UBX domain protein 1
USP46 ubiquitin specific peptidase 46
VRTN vertebrae development associated
XCR1 chemokine (C motif) receptor 1
XDH xanthine dehydrogenase
YIPF2 Yip1 domain family, member 2
ZNF154 zinc finger protein 154

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ACKR3 atypical chemokine receptor 3
ADAP2 ArfGAP with dual PH domains 2
ANKRD26 ankyrin repeat domain 26
AP1AR adaptor-related protein complex 1 associated regulatory protein
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARL14 ADP-ribosylation factor-like 14
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BEX4 brain expressed, X-linked 4
BMP15 bone morphogenetic protein 15
CAPN15 calpain 15
CBR4 carbonyl reductase 4
CDADC1 cytidine and dCMP deaminase domain containing 1
CDK3 cyclin-dependent kinase 3
CDON cell adhesion associated, oncogene regulated
CEP131 centrosomal protein 131kDa
CLDN8 claudin 8
CLSPN claspin
CNGB3 cyclic nucleotide gated channel beta 3
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CORT cortistatin
CRYBB2P1 crystallin, beta B2 pseudogene 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DUSP8 dual specificity phosphatase 8
EFNA3 ephrin-A3
EHD3 EH-domain containing 3
EXD3 exonuclease 3'-5' domain containing 3
FAM184A family with sequence similarity 184, member A
FRS3 fibroblast growth factor receptor substrate 3
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GMIP GEM interacting protein
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GRAMD1C GRAM domain containing 1C
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H2BM histone cluster 1, H2bm
HOXA6 homeobox A6
HOXC13 homeobox C13
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFNA14 interferon, alpha 14
IGSF3 immunoglobulin superfamily, member 3
IL15RA interleukin 15 receptor, alpha
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IPO8 importin 8
KLF3 Kruppel-like factor 3 (basic)
KLHL28 kelch-like family member 28
KRT31 keratin 31, type I
KRT4 keratin 4, type II
LIPG lipase, endothelial
MBTPS2 membrane-bound transcription factor peptidase, site 2
MILR1 mast cell immunoglobulin-like receptor 1
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MON1B MON1 secretory trafficking family member B
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MYL5 myosin, light chain 5, regulatory
MYO1D myosin ID
NR3C2 nuclear receptor subfamily 3, group C, member 2
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
NXPH4 neurexophilin 4
OTUD3 OTU deubiquitinase 3
P3H2 prolyl 3-hydroxylase 2
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PRR7 proline rich 7 (synaptic)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAB3A RAB3A, member RAS oncogene family
RNF2 ring finger protein 2
RWDD2A RWD domain containing 2A
SCN9A sodium channel, voltage gated, type IX alpha subunit
SH3BGR SH3 domain binding glutamate-rich protein
SHPK sedoheptulokinase
SLC46A3 solute carrier family 46, member 3
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SNHG3 small nucleolar RNA host gene 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TCEAL2 transcription elongation factor A (SII)-like 2
TEP1 telomerase-associated protein 1
TMEM159 transmembrane protein 159
TMEM183A transmembrane protein 183A
TMEM53 transmembrane protein 53
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TUBB2B tubulin, beta 2B class IIb
TWISTNB TWIST neighbor
TXLNG taxilin gamma
USB1 U6 snRNA biogenesis 1
USP6NL USP6 N-terminal like
USP8 ubiquitin specific peptidase 8
WDR78 WD repeat domain 78
WFDC2 WAP four-disulfide core domain 2
WNT10B wingless-type MMTV integration site family, member 10B
ZNF215 zinc finger protein 215
ZNF276 zinc finger protein 276
ZNF358 zinc finger protein 358
ZNF552 zinc finger protein 552
ZNF701 zinc finger protein 701