| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the ethambutol-1481 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM28 | ADAM metallopeptidase domain 28 |
| ADORA3 | adenosine A3 receptor |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ARL3 | ADP-ribosylation factor-like 3 |
| ARMC4 | armadillo repeat containing 4 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| BGN | biglycan |
| BTG3 | BTG family, member 3 |
| C5AR2 | complement component 5a receptor 2 |
| CCDC71 | coiled-coil domain containing 71 |
| CD48 | CD48 molecule |
| CDK13 | cyclin-dependent kinase 13 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CEP41 | centrosomal protein 41kDa |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DMPK | dystrophia myotonica-protein kinase |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DOK2 | docking protein 2, 56kDa |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ERCC2 | excision repair cross-complementation group 2 |
| EWSR1 | EWS RNA-binding protein 1 |
| FAM134B | family with sequence similarity 134, member B |
| FAM184A | family with sequence similarity 184, member A |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FN1 | fibronectin 1 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| GIPR | gastric inhibitory polypeptide receptor |
| GK | glycerol kinase |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HDAC11 | histone deacetylase 11 |
| KATNB1 | katanin p80 (WD repeat containing) subunit B 1 |
| KCNH1 | potassium channel, voltage gated eag related subfamily H, member 1 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LMAN1 | lectin, mannose-binding, 1 |
| LOXL3 | lysyl oxidase-like 3 |
| LRP6 | low density lipoprotein receptor-related protein 6 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MBD1 | methyl-CpG binding domain protein 1 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| METTL7A | methyltransferase like 7A |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MLN | motilin |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MSI1 | musashi RNA-binding protein 1 |
| MTL5 | metallothionein-like 5, testis-specific (tesmin) |
| MYH15 | myosin, heavy chain 15 |
| N4BP3 | NEDD4 binding protein 3 |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NMT1 | N-myristoyltransferase 1 |
| NMT2 | N-myristoyltransferase 2 |
| NOL10 | nucleolar protein 10 |
| NPHP1 | nephronophthisis 1 (juvenile) |
| PARVA | parvin, alpha |
| PAX9 | paired box 9 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 |
| PLIN2 | perilipin 2 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| RAB40C | RAB40C, member RAS oncogene family |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RECQL5 | RecQ protein-like 5 |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RNF122 | ring finger protein 122 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SLC13A3 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 |
| SLC6A2 | solute carrier family 6 (neurotransmitter transporter), member 2 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SNPH | syntaphilin |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SOX15 | SRY (sex determining region Y)-box 15 |
| SOX2 | SRY (sex determining region Y)-box 2 |
| SYNDIG1 | synapse differentiation inducing 1 |
| TADA3 | transcriptional adaptor 3 |
| TAOK2 | TAO kinase 2 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TPSG1 | tryptase gamma 1 |
| TSPAN9 | tetraspanin 9 |
| TTC38 | tetratricopeptide repeat domain 38 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| USP34 | ubiquitin specific peptidase 34 |
| WNT6 | wingless-type MMTV integration site family, member 6 |
| XYLT1 | xylosyltransferase I |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ANXA1 | annexin A1 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATF3 | activating transcription factor 3 |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| AZI2 | 5-azacytidine induced 2 |
| BBS7 | Bardet-Biedl syndrome 7 |
| BMP4 | bone morphogenetic protein 4 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C5ORF28 | chromosome 5 open reading frame 28 |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CFD | complement factor D (adipsin) |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLSPN | claspin |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| DCAF16 | DDB1 and CUL4 associated factor 16 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| ECI2 | enoyl-CoA delta isomerase 2 |
| EFNA3 | ephrin-A3 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| FAIM | Fas apoptotic inhibitory molecule |
| FAM188A | family with sequence similarity 188, member A |
| FBXO3 | F-box protein 3 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 |
| HSPA2 | heat shock 70kDa protein 2 |
| IRX4 | iroquois homeobox 4 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLHL21 | kelch-like family member 21 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LIN7A | lin-7 homolog A (C. elegans) |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| MED18 | mediator complex subunit 18 |
| MEFV | Mediterranean fever |
| MEIS2 | Meis homeobox 2 |
| MNT | MAX network transcriptional repressor |
| MTCL1 | microtubule crosslinking factor 1 |
| MYO1D | myosin ID |
| NDE1 | nudE neurodevelopment protein 1 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NOTCH1 | notch 1 |
| NSUN3 | NOP2/Sun domain family, member 3 |
| PCDHA6 | protocadherin alpha 6 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PLD2 | phospholipase D2 |
| PMCH | pro-melanin-concentrating hormone |
| PRMT7 | protein arginine methyltransferase 7 |
| PRPH | peripherin |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RGL2 | ral guanine nucleotide dissociation stimulator-like 2 |
| RGS19 | regulator of G-protein signaling 19 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF2 | ring finger protein 2 |
| RPAP1 | RNA polymerase II associated protein 1 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SMUG1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SNX16 | sorting nexin 16 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPRYD7 | SPRY domain containing 7 |
| STXBP2 | syntaxin binding protein 2 |
| TET3 | tet methylcytosine dioxygenase 3 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TLN1 | talin 1 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| USP36 | ubiquitin specific peptidase 36 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF165 | zinc finger protein 165 |
| ZNF226 | zinc finger protein 226 |
| ZNF248 | zinc finger protein 248 |
| ZNF552 | zinc finger protein 552 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
