| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the ethambutol-1900 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| ACACB | acetyl-CoA carboxylase beta |
| ACVR2B | activin A receptor, type IIB |
| AGGF1 | angiogenic factor with G patch and FHA domains 1 |
| AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ANKRD12 | ankyrin repeat domain 12 |
| APOM | apolipoprotein M |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
| ARMC4 | armadillo repeat containing 4 |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| BEAN1 | brain expressed, associated with NEDD4, 1 |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| C20ORF27 | chromosome 20 open reading frame 27 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CADM3 | cell adhesion molecule 3 |
| CAPN2 | calpain 2, (m/II) large subunit |
| CAPN5 | calpain 5 |
| CCDC101 | coiled-coil domain containing 101 |
| CCZ1 | CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) |
| CD53 | CD53 molecule |
| CDK18 | cyclin-dependent kinase 18 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CELF2 | CUGBP, Elav-like family member 2 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| COL8A2 | collagen, type VIII, alpha 2 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| FAM53B | family with sequence similarity 53, member B |
| FPGS | folylpolyglutamate synthase |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
| GGA3 | golgi-associated, gamma adaptin ear containing, ARF binding protein 3 |
| HFE | hemochromatosis |
| HIRIP3 | HIRA interacting protein 3 |
| HSF2 | heat shock transcription factor 2 |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| HTR6 | 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| IL1RN | interleukin 1 receptor antagonist |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KLF6 | Kruppel-like factor 6 |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 |
| LRRN3 | leucine rich repeat neuronal 3 |
| LZTS1 | leucine zipper, putative tumor suppressor 1 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MMP25 | matrix metallopeptidase 25 |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NEBL | nebulette |
| NPAP1 | nuclear pore associated protein 1 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
| NXT2 | nuclear transport factor 2-like export factor 2 |
| OLFM1 | olfactomedin 1 |
| OLFML2A | olfactomedin-like 2A |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PAM | peptidylglycine alpha-amidating monooxygenase |
| PIDD1 | p53-induced death domain protein 1 |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PRDM2 | PR domain containing 2, with ZNF domain |
| RAD50 | RAD50 homolog (S. cerevisiae) |
| RAMP3 | receptor (G protein-coupled) activity modifying protein 3 |
| RARG | retinoic acid receptor, gamma |
| RIPK2 | receptor-interacting serine-threonine kinase 2 |
| ROBO4 | roundabout, axon guidance receptor, homolog 4 (Drosophila) |
| RPL31 | ribosomal protein L31 |
| SCARB2 | scavenger receptor class B, member 2 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SMC2 | structural maintenance of chromosomes 2 |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SRF | serum response factor (c-fos serum response element-binding transcription factor) |
| STX2 | syntaxin 2 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TEX40 | testis expressed 40 |
| THRB | thyroid hormone receptor, beta |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TRIM10 | tripartite motif containing 10 |
| TRIM29 | tripartite motif containing 29 |
| TRPM3 | transient receptor potential cation channel, subfamily M, member 3 |
| TSPAN15 | tetraspanin 15 |
| USF2 | upstream transcription factor 2, c-fos interacting |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 |
| WIZ | widely interspaced zinc finger motifs |
| XDH | xanthine dehydrogenase |
| ZNF304 | zinc finger protein 304 |
| ZNF562 | zinc finger protein 562 |
| ZNF710 | zinc finger protein 710 |
| ZNF721 | zinc finger protein 721 |
| Symbol | Name |
|---|---|
| AHCTF1 | AT hook containing transcription factor 1 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ATG7 | autophagy related 7 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase |
| BCL7C | B-cell CLL/lymphoma 7C |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C17ORF62 | chromosome 17 open reading frame 62 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CDC45 | cell division cycle 45 |
| CDCA3 | cell division cycle associated 3 |
| CEP85 | centrosomal protein 85kDa |
| CLDND1 | claudin domain containing 1 |
| CLK3 | CDC-like kinase 3 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| COCH | cochlin |
| COLGALT1 | collagen beta(1-O)galactosyltransferase 1 |
| COMMD10 | COMM domain containing 10 |
| CPOX | coproporphyrinogen oxidase |
| CSNK1G3 | casein kinase 1, gamma 3 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DESI1 | desumoylating isopeptidase 1 |
| DIXDC1 | DIX domain containing 1 |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| FAM46A | family with sequence similarity 46, member A |
| FAR2 | fatty acyl CoA reductase 2 |
| GALNS | galactosamine (N-acetyl)-6-sulfatase |
| GAMT | guanidinoacetate N-methyltransferase |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GSTK1 | glutathione S-transferase kappa 1 |
| GSTT1 | glutathione S-transferase theta 1 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 |
| HAUS4 | HAUS augmin-like complex, subunit 4 |
| HERC2 | HECT and RLD domain containing E3 ubiquitin protein ligase 2 |
| ING3 | inhibitor of growth family, member 3 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITGAV | integrin, alpha V |
| KRT34 | keratin 34, type I |
| LMBRD1 | LMBR1 domain containing 1 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| MAD2L1BP | MAD2L1 binding protein |
| MDK | midkine (neurite growth-promoting factor 2) |
| MPP1 | membrane protein, palmitoylated 1, 55kDa |
| MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| MSN | moesin |
| MT1HL1 | metallothionein 1H-like 1 |
| NIPA2 | non imprinted in Prader-Willi/Angelman syndrome 2 |
| NRAS | neuroblastoma RAS viral (v-ras) oncogene homolog |
| ORC3 | origin recognition complex, subunit 3 |
| PAQR3 | progestin and adipoQ receptor family member III |
| PCNA | proliferating cell nuclear antigen |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PIKFYVE | phosphoinositide kinase, FYVE finger containing |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| PSMC2 | proteasome (prosome, macropain) 26S subunit, ATPase, 2 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| R3HCC1 | R3H domain and coiled-coil containing 1 |
| RAB5B | RAB5B, member RAS oncogene family |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SATB1 | SATB homeobox 1 |
| SELENBP1 | selenium binding protein 1 |
| SH2B3 | SH2B adaptor protein 3 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SLC35E3 | solute carrier family 35, member E3 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SLIRP | SRA stem-loop interacting RNA binding protein |
| SNRPC | small nuclear ribonucleoprotein polypeptide C |
| SOAT1 | sterol O-acyltransferase 1 |
| SPAG1 | sperm associated antigen 1 |
| STK16 | serine/threonine kinase 16 |
| STXBP3 | syntaxin binding protein 3 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| SURF2 | surfeit 2 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) |
| TFB2M | transcription factor B2, mitochondrial |
| TGDS | TDP-glucose 4,6-dehydratase |
| TMBIM4 | transmembrane BAX inhibitor motif containing 4 |
| TMEM115 | transmembrane protein 115 |
| TMEM168 | transmembrane protein 168 |
| TOP2B | topoisomerase (DNA) II beta 180kDa |
| TOPBP1 | topoisomerase (DNA) II binding protein 1 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) |
| TSC22D1 | TSC22 domain family, member 1 |
| UBAC1 | UBA domain containing 1 |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| USP39 | ubiquitin specific peptidase 39 |
| ZNF266 | zinc finger protein 266 |
| ZW10 | zw10 kinetochore protein |
