| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the ethambutol-1981 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACVR1B | activin A receptor, type IB |
| ADRBK2 | adrenergic, beta, receptor kinase 2 |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 |
| ATG13 | autophagy related 13 |
| ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A |
| BCL3 | B-cell CLL/lymphoma 3 |
| BPTF | bromodomain PHD finger transcription factor |
| CCDC64 | coiled-coil domain containing 64 |
| CCNF | cyclin F |
| CDK10 | cyclin-dependent kinase 10 |
| CDK9 | cyclin-dependent kinase 9 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CENPT | centromere protein T |
| CFAP74 | cilia and flagella associated protein 74 |
| CHKA | choline kinase alpha |
| CIR1 | corepressor interacting with RBPJ, 1 |
| COMMD4 | COMM domain containing 4 |
| CPT2 | carnitine palmitoyltransferase 2 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CTRC | chymotrypsin C (caldecrin) |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 |
| DRD2 | dopamine receptor D2 |
| DUSP2 | dual specificity phosphatase 2 |
| EEF2 | eukaryotic translation elongation factor 2 |
| ELMO2 | engulfment and cell motility 2 |
| ENOX2 | ecto-NOX disulfide-thiol exchanger 2 |
| FAM105A | family with sequence similarity 105, member A |
| FAM89B | family with sequence similarity 89, member B |
| FASTK | Fas-activated serine/threonine kinase |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FBXO41 | F-box protein 41 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| FJX1 | four jointed box 1 (Drosophila) |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GSDMD | gasdermin D |
| GSTZ1 | glutathione S-transferase zeta 1 |
| GTF3C1 | general transcription factor IIIC, polypeptide 1, alpha 220kDa |
| HBB | hemoglobin, beta |
| HIGD2A | HIG1 hypoxia inducible domain family, member 2A |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HPS4 | Hermansky-Pudlak syndrome 4 |
| HSF1 | heat shock transcription factor 1 |
| HTT | huntingtin |
| ING4 | inhibitor of growth family, member 4 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) |
| LENEP | lens epithelial protein |
| LMAN1 | lectin, mannose-binding, 1 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 |
| MAZ | MYC-associated zinc finger protein (purine-binding transcription factor) |
| MDC1 | mediator of DNA-damage checkpoint 1 |
| MECP2 | methyl CpG binding protein 2 |
| MED16 | mediator complex subunit 16 |
| METTL13 | methyltransferase like 13 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase |
| MRPS12 | mitochondrial ribosomal protein S12 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NCOA3 | nuclear receptor coactivator 3 |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NGLY1 | N-glycanase 1 |
| NXPH3 | neurexophilin 3 |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| POR | P450 (cytochrome) oxidoreductase |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha |
| PRKD2 | protein kinase D2 |
| PRODH2 | proline dehydrogenase (oxidase) 2 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RCOR3 | REST corepressor 3 |
| SGSM3 | small G protein signaling modulator 3 |
| SH2B1 | SH2B adaptor protein 1 |
| SHARPIN | SHANK-associated RH domain interactor |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 |
| SLC25A44 | solute carrier family 25, member 44 |
| SLC7A6 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 |
| SNX17 | sorting nexin 17 |
| SRCAP | Snf2-related CREBBP activator protein |
| SUGP1 | SURP and G patch domain containing 1 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TMEM104 | transmembrane protein 104 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TRABD | TraB domain containing |
| TSC2 | tuberous sclerosis 2 |
| TSTA3 | tissue specific transplantation antigen P35B |
| XYLT2 | xylosyltransferase II |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZSCAN5A | zinc finger and SCAN domain containing 5A |
| Symbol | Name |
|---|---|
| ABCD3 | ATP-binding cassette, sub-family D (ALD), member 3 |
| ABHD3 | abhydrolase domain containing 3 |
| ACTL6A | actin-like 6A |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type |
| ANKRD11 | ankyrin repeat domain 11 |
| ANXA2P2 | annexin A2 pseudogene 2 |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ATAD2B | ATPase family, AAA domain containing 2B |
| ATF1 | activating transcription factor 1 |
| BTK | Bruton agammaglobulinemia tyrosine kinase |
| C5ORF28 | chromosome 5 open reading frame 28 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CCDC28A | coiled-coil domain containing 28A |
| CD151 | CD151 molecule (Raph blood group) |
| CDC73 | cell division cycle 73 |
| CENPQ | centromere protein Q |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| DCK | deoxycytidine kinase |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 |
| DNAJC13 | DnaJ (Hsp40) homolog, subfamily C, member 13 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DPYD | dihydropyrimidine dehydrogenase |
| FAM3C | family with sequence similarity 3, member C |
| FBXO46 | F-box protein 46 |
| FBXW4 | F-box and WD repeat domain containing 4 |
| FTH1P5 | ferritin, heavy polypeptide 1 pseudogene 5 |
| FUBP3 | far upstream element (FUSE) binding protein 3 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GCLM | glutamate-cysteine ligase, modifier subunit |
| HEATR3 | HEAT repeat containing 3 |
| HIRA | histone cell cycle regulator |
| IFT46 | intraflagellar transport 46 |
| IGBP1 | immunoglobulin (CD79A) binding protein 1 |
| INO80D | INO80 complex subunit D |
| KCTD5 | potassium channel tetramerization domain containing 5 |
| KIAA0196 | KIAA0196 |
| KIAA0753 | KIAA0753 |
| KIAA0894 | KIAA0894 protein |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| KTN1 | kinectin 1 (kinesin receptor) |
| LACTB2 | lactamase, beta 2 |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) |
| LYRM2 | LYR motif containing 2 |
| LYZ | lysozyme |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MEX3C | mex-3 RNA binding family member C |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NUCB2 | nucleobindin 2 |
| OAT | ornithine aminotransferase |
| OGFRL1 | opioid growth factor receptor-like 1 |
| OXR1 | oxidation resistance 1 |
| PBX3 | pre-B-cell leukemia homeobox 3 |
| PHACTR4 | phosphatase and actin regulator 4 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PTPN4 | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RBL1 | retinoblastoma-like 1 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RPAP3 | RNA polymerase II associated protein 3 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPS17P5 | ribosomal protein S17 pseudogene 5 |
| RPS25 | ribosomal protein S25 |
| RRN3 | RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 |
| SELP | selectin P (granule membrane protein 140kDa, antigen CD62) |
| SH3YL1 | SH3 and SYLF domain containing 1 |
| SIRT6 | sirtuin 6 |
| SLMO2 | slowmo homolog 2 (Drosophila) |
| SP3 | Sp3 transcription factor |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| STXBP3 | syntaxin binding protein 3 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TBCCD1 | TBCC domain containing 1 |
| TMEM14A | transmembrane protein 14A |
| TMEM184B | transmembrane protein 184B |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| TSLIG2 | tRNA splicing ligase complex subunit 2 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 |
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) |
| VASP | vasodilator-stimulated phosphoprotein |
| VCPKMT | valosin containing protein lysine (K) methyltransferase |
| WBP2 | WW domain binding protein 2 |
| WDR82 | WD repeat domain 82 |
| YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF443 | zinc finger protein 443 |
| ZNF721 | zinc finger protein 721 |
