| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the ethambutol-4001 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| AAK1 | AP2 associated kinase 1 |
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ANGPT4 | angiopoietin 4 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 |
| ARHGAP6 | Rho GTPase activating protein 6 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| C10ORF12 | chromosome 10 open reading frame 12 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CADM1 | cell adhesion molecule 1 |
| CBS | cystathionine-beta-synthase |
| CCDC28B | coiled-coil domain containing 28B |
| CDY1 | chromodomain protein, Y-linked, 1 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CFHR2 | complement factor H-related 2 |
| CRISP2 | cysteine-rich secretory protein 2 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) |
| DENND2A | DENN/MADD domain containing 2A |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DIO3 | deiodinase, iodothyronine, type III |
| DMP1 | dentin matrix acidic phosphoprotein 1 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DTNA | dystrobrevin, alpha |
| DTX2P1-UPK3BP1-PMS2P11 | DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene |
| EML3 | echinoderm microtubule associated protein like 3 |
| EVI2B | ecotropic viral integration site 2B |
| FAM134B | family with sequence similarity 134, member B |
| FBXO40 | F-box protein 40 |
| FMO5 | flavin containing monooxygenase 5 |
| FN1 | fibronectin 1 |
| FOXO4 | forkhead box O4 |
| GAB1 | GRB2-associated binding protein 1 |
| GHRHR | growth hormone releasing hormone receptor |
| GLP1R | glucagon-like peptide 1 receptor |
| GPR135 | G protein-coupled receptor 135 |
| HAP1 | huntingtin-associated protein 1 |
| HIST1H4A | histone cluster 1, H4a |
| HIST1H4D | histone cluster 1, H4d |
| HOXB6 | homeobox B6 |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
| KIFC3 | kinesin family member C3 |
| KLK12 | kallikrein-related peptidase 12 |
| LDB1 | LIM domain binding 1 |
| LDB2 | LIM domain binding 2 |
| LIMD1 | LIM domains containing 1 |
| LINC00302 | long intergenic non-protein coding RNA 302 |
| LINC00652 | long intergenic non-protein coding RNA 652 |
| LPP | LIM domain containing preferred translocation partner in lipoma |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MPZ | myelin protein zero |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| OTUD7B | OTU deubiquitinase 7B |
| PCDH1 | protocadherin 1 |
| PDE10A | phosphodiesterase 10A |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PRAMEF11 | PRAME family member 11 |
| PRKCE | protein kinase C, epsilon |
| PRKCI | protein kinase C, iota |
| PRTN3 | proteinase 3 |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PTK2B | protein tyrosine kinase 2 beta |
| RARB | retinoic acid receptor, beta |
| RGS12 | regulator of G-protein signaling 12 |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E |
| SPIDR | scaffolding protein involved in DNA repair |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STK17A | serine/threonine kinase 17a |
| STS | steroid sulfatase (microsomal), isozyme S |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TCEAL2 | transcription elongation factor A (SII)-like 2 |
| THBS3 | thrombospondin 3 |
| THSD4 | thrombospondin, type I, domain containing 4 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TNK2 | tyrosine kinase, non-receptor, 2 |
| TNNT3 | troponin T type 3 (skeletal, fast) |
| TRIM15 | tripartite motif containing 15 |
| TRPM3 | transient receptor potential cation channel, subfamily M, member 3 |
| TTC30A | tetratricopeptide repeat domain 30A |
| UCP1 | uncoupling protein 1 (mitochondrial, proton carrier) |
| UHRF1BP1L | UHRF1 binding protein 1-like |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
| VAX2 | ventral anterior homeobox 2 |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZNF24 | zinc finger protein 24 |
| ZNF334 | zinc finger protein 334 |
| ZNF749 | zinc finger protein 749 |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| APOC4 | apolipoprotein C-IV |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGAP24 | Rho GTPase activating protein 24 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ARRB2 | arrestin, beta 2 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| B9D2 | B9 protein domain 2 |
| BMP15 | bone morphogenetic protein 15 |
| CA9 | carbonic anhydrase IX |
| CCNJL | cyclin J-like |
| CEL | carboxyl ester lipase |
| CINP | cyclin-dependent kinase 2 interacting protein |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CYB5R2 | cytochrome b5 reductase 2 |
| DBF4B | DBF4 zinc finger B |
| DEAF1 | DEAF1 transcription factor |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DOCK1 | dedicator of cytokinesis 1 |
| EFNB1 | ephrin-B1 |
| EVPL | envoplakin |
| FA2H | fatty acid 2-hydroxylase |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GJA9 | gap junction protein, alpha 9, 59kDa |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRM4 | glutamate receptor, metabotropic 4 |
| GUCY1A2 | guanylate cyclase 1, soluble, alpha 2 |
| HOXC10 | homeobox C10 |
| HOXC13 | homeobox C13 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA1644 | KIAA1644 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MN1 | meningioma (disrupted in balanced translocation) 1 |
| MXRA8 | matrix-remodelling associated 8 |
| NAG18 | NAG18 mRNA |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase |
| NINJ1 | ninjurin 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NUBP2 | nucleotide binding protein 2 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PEX26 | peroxisomal biogenesis factor 26 |
| PLA2G15 | phospholipase A2, group XV |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PLXNB3 | plexin B3 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| POLL | polymerase (DNA directed), lambda |
| PRR4 | proline rich 4 (lacrimal) |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RGCC | regulator of cell cycle |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) |
| RIN1 | Ras and Rab interactor 1 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| RUSC2 | RUN and SH3 domain containing 2 |
| SCARA3 | scavenger receptor class A, member 3 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLAMF7 | SLAM family member 7 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
| SSTR4 | somatostatin receptor 4 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TBC1D17 | TBC1 domain family, member 17 |
| TBC1D8B | TBC1 domain family, member 8B (with GRAM domain) |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TMEM212 | transmembrane protein 212 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TXK | TXK tyrosine kinase |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| WFDC2 | WAP four-disulfide core domain 2 |
| WNT1 | wingless-type MMTV integration site family, member 1 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF10 | zinc finger protein 10 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF510 | zinc finger protein 510 |
| ZNF529 | zinc finger protein 529 |
