ethaverine-5337 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the ethaverine-5337 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AK2 adenylate kinase 2
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APLP1 amyloid beta (A4) precursor-like protein 1
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BICD1 bicaudal D homolog 1 (Drosophila)
BLVRA biliverdin reductase A
BTBD7 BTB (POZ) domain containing 7
CACTIN cactin, spliceosome C complex subunit
CAMTA2 calmodulin binding transcription activator 2
CASKIN2 CASK interacting protein 2
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC25 coiled-coil domain containing 25
CCDC85C coiled-coil domain containing 85C
CCL27 chemokine (C-C motif) ligand 27
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEP164 centrosomal protein 164kDa
CHPF2 chondroitin polymerizing factor 2
CNTN1 contactin 1
CPTP ceramide-1-phosphate transfer protein
CRYGC crystallin, gamma C
CXXC1 CXXC finger protein 1
DGKE diacylglycerol kinase, epsilon 64kDa
DNAL4 dynein, axonemal, light chain 4
DNM1 dynamin 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DVL2 dishevelled segment polarity protein 2
EHD1 EH-domain containing 1
ELF4 E74-like factor 4 (ets domain transcription factor)
EML3 echinoderm microtubule associated protein like 3
EXOC7 exocyst complex component 7
FOSL2 FOS-like antigen 2
FZD7 frizzled class receptor 7
GAS6 growth arrest-specific 6
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GUSBP3 glucuronidase, beta pseudogene 3
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
INO80D INO80 complex subunit D
IRF6 interferon regulatory factor 6
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KDM4B lysine (K)-specific demethylase 4B
KLF3 Kruppel-like factor 3 (basic)
KRT6B keratin 6B, type II
LAMA3 laminin, alpha 3
LDB1 LIM domain binding 1
LPCAT4 lysophosphatidylcholine acyltransferase 4
LRRC61 leucine rich repeat containing 61
LYST lysosomal trafficking regulator
MAP1B microtubule-associated protein 1B
MAP4 microtubule-associated protein 4
MAST4 microtubule associated serine/threonine kinase family member 4
MITF microphthalmia-associated transcription factor
MYH14 myosin, heavy chain 14, non-muscle
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOP16 NOP16 nucleolar protein
NPIPB15 nuclear pore complex interacting protein family, member B15
OSMR oncostatin M receptor
PAX5 paired box 5
PC pyruvate carboxylase
PDCD2 programmed cell death 2
PDLIM7 PDZ and LIM domain 7 (enigma)
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA2G10 phospholipase A2, group X
PLEKHO1 pleckstrin homology domain containing, family O member 1
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
POFUT2 protein O-fucosyltransferase 2
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PTGIS prostaglandin I2 (prostacyclin) synthase
RANGRF RAN guanine nucleotide release factor
RBM19 RNA binding motif protein 19
RGS12 regulator of G-protein signaling 12
RGS3 regulator of G-protein signaling 3
RIPK4 receptor-interacting serine-threonine kinase 4
RNF31 ring finger protein 31
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SCN10A sodium channel, voltage gated, type X alpha subunit
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SOX12 SRY (sex determining region Y)-box 12
STBD1 starch binding domain 1
SUGP1 SURP and G patch domain containing 1
TMEM104 transmembrane protein 104
TMEM63A transmembrane protein 63A
TMEM80 transmembrane protein 80
TP53I11 tumor protein p53 inducible protein 11
TTC38 tetratricopeptide repeat domain 38
USB1 U6 snRNA biogenesis 1
USP20 ubiquitin specific peptidase 20
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
XYLB xylulokinase homolog (H. influenzae)
ZBTB43 zinc finger and BTB domain containing 43
ZNF250 zinc finger protein 250
ZNF34 zinc finger protein 34
ZNF589 zinc finger protein 589
ZNRD1-AS1 ZNRD1 antisense RNA 1

decreased expression

Symbol Name
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ACYP2 acylphosphatase 2, muscle type
ADAM15 ADAM metallopeptidase domain 15
AIDA axin interactor, dorsalization associated
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ATAD3A ATPase family, AAA domain containing 3A
BTF3P12 basic transcription factor 3 pseudogene 12
C10ORF88 chromosome 10 open reading frame 88
C11ORF73 chromosome 11 open reading frame 73
C16ORF59 chromosome 16 open reading frame 59
C1ORF159 chromosome 1 open reading frame 159
C1ORF56 chromosome 1 open reading frame 56
C4ORF29 chromosome 4 open reading frame 29
CBR4 carbonyl reductase 4
CD82 CD82 molecule
CDK20 cyclin-dependent kinase 20
CENPJ centromere protein J
CEP97 centrosomal protein 97kDa
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CRELD1 cysteine-rich with EGF-like domains 1
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
CTNNBIP1 catenin, beta interacting protein 1
DCP1A decapping mRNA 1A
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
FAM188A family with sequence similarity 188, member A
FAM53B family with sequence similarity 53, member B
FIP1L1 factor interacting with PAPOLA and CPSF1
FKBP10 FK506 binding protein 10, 65 kDa
FLRT3 fibronectin leucine rich transmembrane protein 3
FZD3 frizzled class receptor 3
GAR1 GAR1 ribonucleoprotein
GDAP1 ganglioside induced differentiation associated protein 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPHN gephyrin
HHEX hematopoietically expressed homeobox
HIST1H2BI histone cluster 1, H2bi
HIST2H2AA3 histone cluster 2, H2aa3
IFI6 interferon, alpha-inducible protein 6
KCTD20 potassium channel tetramerization domain containing 20
KIFC1 kinesin family member C1
KPNA4 karyopherin alpha 4 (importin alpha 3)
LIG4 ligase IV, DNA, ATP-dependent
LMNB1 lamin B1
MAN2C1 mannosidase, alpha, class 2C, member 1
MANEA mannosidase, endo-alpha
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MBTPS2 membrane-bound transcription factor peptidase, site 2
MEIS1 Meis homeobox 1
MTERF1 mitochondrial transcription termination factor 1
MXD3 MAX dimerization protein 3
NHLRC2 NHL repeat containing 2
NPM3 nucleophosmin/nucleoplasmin 3
NRGN neurogranin (protein kinase C substrate, RC3)
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PECR peroxisomal trans-2-enoyl-CoA reductase
PLA2G12A phospholipase A2, group XIIA
PRSS8 protease, serine, 8
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
PYGL phosphorylase, glycogen, liver
RASA2 RAS p21 protein activator 2
RINT1 RAD50 interactor 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF121 ring finger protein 121
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
RWDD2A RWD domain containing 2A
SETD1B SET domain containing 1B
SGK1 serum/glucocorticoid regulated kinase 1
SH2D4A SH2 domain containing 4A
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC35F5 solute carrier family 35, member F5
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SMAD5 SMAD family member 5
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMG9 SMG9 nonsense mediated mRNA decay factor
SNHG3 small nucleolar RNA host gene 3
SNUPN snurportin 1
SOAT1 sterol O-acyltransferase 1
SPATA7 spermatogenesis associated 7
THNSL1 threonine synthase-like 1 (S. cerevisiae)
THRAP3 thyroid hormone receptor associated protein 3
TIGAR TP53 induced glycolysis regulatory phosphatase
TMEM230 transmembrane protein 230
TRAF5 TNF receptor-associated factor 5
TXNIP thioredoxin interacting protein
UBXN8 UBX domain protein 8
VCPKMT valosin containing protein lysine (K) methyltransferase
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZMAT5 zinc finger, matrin-type 5
ZNF124 zinc finger protein 124
ZNF165 zinc finger protein 165
ZNF480 zinc finger protein 480
ZNF675 zinc finger protein 675