ethaverine-6737 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the ethaverine-6737 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ACSM3 acyl-CoA synthetase medium-chain family member 3
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ANGPT4 angiopoietin 4
ANGPTL4 angiopoietin-like 4
ANKZF1 ankyrin repeat and zinc finger domain containing 1
AQP3 aquaporin 3 (Gill blood group)
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARMC4 armadillo repeat containing 4
ASCL1 achaete-scute family bHLH transcription factor 1
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BLZF1 basic leucine zipper nuclear factor 1
BTF3P11 basic transcription factor 3 pseudogene 11
C14ORF79 chromosome 14 open reading frame 79
CD1C CD1c molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD58 CD58 molecule
CDY1 chromodomain protein, Y-linked, 1
CEP152 centrosomal protein 152kDa
CLCA2 chloride channel accessory 2
CLCN7 chloride channel, voltage-sensitive 7
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DMBT1 deleted in malignant brain tumors 1
DNASE1L3 deoxyribonuclease I-like 3
DOK4 docking protein 4
DRICH1 aspartate-rich 1
DSG3 desmoglein 3
DTX3 deltex 3, E3 ubiquitin ligase
DUSP1 dual specificity phosphatase 1
DUSP26 dual specificity phosphatase 26 (putative)
EFNB1 ephrin-B1
EYA4 EYA transcriptional coactivator and phosphatase 4
F5 coagulation factor V (proaccelerin, labile factor)
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FGF8 fibroblast growth factor 8 (androgen-induced)
FLJ11710 uncharacterized protein FLJ11710
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
GHRHR growth hormone releasing hormone receptor
GK glycerol kinase
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPR85 G protein-coupled receptor 85
HIC2 hypermethylated in cancer 2
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HRG histidine-rich glycoprotein
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
IFI44 interferon-induced protein 44
IL11 interleukin 11
IL18R1 interleukin 18 receptor 1
IL33 interleukin 33
ISG20 interferon stimulated exonuclease gene 20kDa
ITGB8 integrin, beta 8
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LCAT lecithin-cholesterol acyltransferase
LHFPL2 lipoma HMGIC fusion partner-like 2
LMO1 LIM domain only 1 (rhombotin 1)
LOC57399 uncharacterized gastric protein ZA52P
LOXL3 lysyl oxidase-like 3
MAP7 microtubule-associated protein 7
MCF2L MCF.2 cell line derived transforming sequence-like
MEF2D myocyte enhancer factor 2D
MMP16 matrix metallopeptidase 16 (membrane-inserted)
NCAPH2 non-SMC condensin II complex, subunit H2
NCR2 natural cytotoxicity triggering receptor 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUDC nudC nuclear distribution protein
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PAIP2B poly(A) binding protein interacting protein 2B
PARP11 poly (ADP-ribose) polymerase family, member 11
PAX4 paired box 4
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE10A phosphodiesterase 10A
PDE4D phosphodiesterase 4D, cAMP-specific
PDE5A phosphodiesterase 5A, cGMP-specific
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLD1 phospholipase D1, phosphatidylcholine-specific
PRO2964 uncharacterized protein PRO2964
PRR5 proline rich 5 (renal)
PTGES prostaglandin E synthase
PTHLH parathyroid hormone-like hormone
PTMS parathymosin
PTP4A1 protein tyrosine phosphatase type IVA, member 1
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RGS12 regulator of G-protein signaling 12
RHOT2 ras homolog family member T2
SCARB1 scavenger receptor class B, member 1
SOSTDC1 sclerostin domain containing 1
SRRT serrate, RNA effector molecule
STAT2 signal transducer and activator of transcription 2, 113kDa
STC1 stanniocalcin 1
TBKBP1 TBK1 binding protein 1
TBL1X transducin (beta)-like 1X-linked
TGFA transforming growth factor, alpha
TGFBR1 transforming growth factor, beta receptor 1
TMPRSS4 transmembrane protease, serine 4
UBA7 ubiquitin-like modifier activating enzyme 7
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
WSB1 WD repeat and SOCS box containing 1
ZBTB17 zinc finger and BTB domain containing 17
ZNF268 zinc finger protein 268

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ADRB2 adrenoceptor beta 2, surface
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
AXIN1 axin 1
BSPRY B-box and SPRY domain containing
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C5ORF42 chromosome 5 open reading frame 42
C5ORF45 chromosome 5 open reading frame 45
CASS4 Cas scaffolding protein family member 4
CCDC85C coiled-coil domain containing 85C
CDK3 cyclin-dependent kinase 3
CLCN5 chloride channel, voltage-sensitive 5
CLCN6 chloride channel, voltage-sensitive 6
CLDN15 claudin 15
CNN1 calponin 1, basic, smooth muscle
CNTNAP3B contactin associated protein-like 3B
CPA4 carboxypeptidase A4
CTGF connective tissue growth factor
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNM3 dynamin 3
ETNK2 ethanolamine kinase 2
EXD3 exonuclease 3'-5' domain containing 3
FAM188A family with sequence similarity 188, member A
FAM53B family with sequence similarity 53, member B
FGF23 fibroblast growth factor 23
FLT4 fms-related tyrosine kinase 4
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GIF gastric intrinsic factor (vitamin B synthesis)
GMPR guanosine monophosphate reductase
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HDAC11 histone deacetylase 11
HDAC9 histone deacetylase 9
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BN histone cluster 1, H2bn
HOXA7 homeobox A7
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HSPB6 heat shock protein, alpha-crystallin-related, B6
IL6 interleukin 6
KIAA1462 KIAA1462
KPNA5 karyopherin alpha 5 (importin alpha 6)
LIG4 ligase IV, DNA, ATP-dependent
LINC00341 long intergenic non-protein coding RNA 341
LRRK1 leucine-rich repeat kinase 1
LY96 lymphocyte antigen 96
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAP1S microtubule-associated protein 1S
MAP3K7CL MAP3K7 C-terminal like
MAP9 microtubule-associated protein 9
MCM9 minichromosome maintenance complex component 9
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MFSD6 major facilitator superfamily domain containing 6
MUC3B mucin 3B, cell surface associated
NABP1 nucleic acid binding protein 1
NARFL nuclear prelamin A recognition factor-like
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NPY1R neuropeptide Y receptor Y1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OVGP1 oviductal glycoprotein 1, 120kDa
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PACS1 phosphofurin acidic cluster sorting protein 1
PALMD palmdelphin
PARM1 prostate androgen-regulated mucin-like protein 1
PCOLCE procollagen C-endopeptidase enhancer
PDE8B phosphodiesterase 8B
PKD2L2 polycystic kidney disease 2-like 2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLXNA3 plexin A3
QSER1 glutamine and serine rich 1
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RAPSN receptor-associated protein of the synapse
RIBC2 RIB43A domain with coiled-coils 2
SCHIP1 schwannomin interacting protein 1
SCN1B sodium channel, voltage gated, type I beta subunit
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SPEG SPEG complex locus
SPTBN2 spectrin, beta, non-erythrocytic 2
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
TESK2 testis-specific kinase 2
TMEM156 transmembrane protein 156
TMEM53 transmembrane protein 53
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRPV6 transient receptor potential cation channel, subfamily V, member 6
UBQLN4 ubiquilin 4
UNC119 unc-119 homolog (C. elegans)
USP20 ubiquitin specific peptidase 20
VEGFB vascular endothelial growth factor B
ZNF197 zinc finger protein 197
ZNF358 zinc finger protein 358
ZNF552 zinc finger protein 552
ZNF770 zinc finger protein 770