| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the ethionamide-4418 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM22 | ADAM metallopeptidase domain 22 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| APAF1 | apoptotic peptidase activating factor 1 |
| ARTN | artemin |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| BNC2 | basonuclin 2 |
| CALB2 | calbindin 2 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CD1A | CD1a molecule |
| CD52 | CD52 molecule |
| CFAP69 | cilia and flagella associated protein 69 |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CLTA | clathrin, light chain A |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CYBB | cytochrome b-245, beta polypeptide |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DEPDC5 | DEP domain containing 5 |
| DFNB31 | deafness, autosomal recessive 31 |
| DGCR14 | DiGeorge syndrome critical region gene 14 |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| ECE1 | endothelin converting enzyme 1 |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 |
| EMCN | endomucin |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FBN1 | fibrillin 1 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FRMD1 | FERM domain containing 1 |
| FYB | FYN binding protein |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
| GM2A | GM2 ganglioside activator |
| GP2 | glycoprotein 2 (zymogen granule membrane) |
| GRIP2 | glutamate receptor interacting protein 2 |
| GRPR | gastrin-releasing peptide receptor |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
| HIC2 | hypermethylated in cancer 2 |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HOXB5 | homeobox B5 |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| IBSP | integrin-binding sialoprotein |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGLJ3 | immunoglobulin lambda joining 3 |
| IL1RAP | interleukin 1 receptor accessory protein |
| ITM2C | integral membrane protein 2C |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 |
| KIAA1109 | KIAA1109 |
| KIF25 | kinesin family member 25 |
| LOC390998 | ribosomal protein L10 pseudogene |
| MCAM | melanoma cell adhesion molecule |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MR1 | major histocompatibility complex, class I-related |
| MT3 | metallothionein 3 |
| MVB12B | multivesicular body subunit 12B |
| MYLK | myosin light chain kinase |
| NCF4 | neutrophil cytosolic factor 4, 40kDa |
| NEIL1 | nei endonuclease VIII-like 1 (E. coli) |
| PAPOLG | poly(A) polymerase gamma |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PPARD | peroxisome proliferator-activated receptor delta |
| RNF17 | ring finger protein 17 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RUNX1 | runt-related transcription factor 1 |
| SECTM1 | secreted and transmembrane 1 |
| SIM2 | single-minded family bHLH transcription factor 2 |
| SIRT4 | sirtuin 4 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SOCS7 | suppressor of cytokine signaling 7 |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SPOCK3 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
| ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
| STAB2 | stabilin 2 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SYN3 | synapsin III |
| TAOK2 | TAO kinase 2 |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase |
| TNPO2 | transportin 2 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TSSK2 | testis-specific serine kinase 2 |
| TTC39A | tetratricopeptide repeat domain 39A |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 |
| UMPS | uridine monophosphate synthetase |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) |
| WDR55 | WD repeat domain 55 |
| WDR59 | WD repeat domain 59 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZFP64 | ZFP64 zinc finger protein |
| ZNF589 | zinc finger protein 589 |
| Symbol | Name |
|---|---|
| ACVR2B | activin A receptor, type IIB |
| ADM | adrenomedullin |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ART1 | ADP-ribosyltransferase 1 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BMP15 | bone morphogenetic protein 15 |
| BST2 | bone marrow stromal cell antigen 2 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CARF | calcium responsive transcription factor |
| CCDC85C | coiled-coil domain containing 85C |
| CCDC9 | coiled-coil domain containing 9 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD82 | CD82 molecule |
| CDHR2 | cadherin-related family member 2 |
| CDK20 | cyclin-dependent kinase 20 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CNTFR | ciliary neurotrophic factor receptor |
| CNTNAP1 | contactin associated protein 1 |
| CPNE7 | copine VII |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CUL9 | cullin 9 |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DGKQ | diacylglycerol kinase, theta 110kDa |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| EGFL7 | EGF-like-domain, multiple 7 |
| ERCC6 | excision repair cross-complementation group 6 |
| ETV6 | ets variant 6 |
| F2R | coagulation factor II (thrombin) receptor |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FGF13 | fibroblast growth factor 13 |
| FRMD8 | FERM domain containing 8 |
| GAS2 | growth arrest-specific 2 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR27 | G protein-coupled receptor 27 |
| GPR3 | G protein-coupled receptor 3 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HIRA | histone cell cycle regulator |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IRF9 | interferon regulatory factor 9 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LMNB1 | lamin B1 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LOXL3 | lysyl oxidase-like 3 |
| MED15 | mediator complex subunit 15 |
| MEGF8 | multiple EGF-like-domains 8 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| N4BP3 | NEDD4 binding protein 3 |
| NKX2-5 | NK2 homeobox 5 |
| NPFFR1 | neuropeptide FF receptor 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PDZD2 | PDZ domain containing 2 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PLA2G1B | phospholipase A2, group IB (pancreas) |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| POLL | polymerase (DNA directed), lambda |
| PRR14L | proline rich 14-like |
| QPCT | glutaminyl-peptide cyclotransferase |
| RAB40C | RAB40C, member RAS oncogene family |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| RHBDD3 | rhomboid domain containing 3 |
| RND1 | Rho family GTPase 1 |
| RNF122 | ring finger protein 122 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SKI | SKI proto-oncogene |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| SPRR2B | small proline-rich protein 2B |
| STRA6 | stimulated by retinoic acid 6 |
| SYNC | syncoilin, intermediate filament protein |
| TAOK1 | TAO kinase 1 |
| TARP | TCR gamma alternate reading frame protein |
| TBC1D2 | TBC1 domain family, member 2 |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| THRB | thyroid hormone receptor, beta |
| TPSG1 | tryptase gamma 1 |
| TRIM5 | tripartite motif containing 5 |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZNF230 | zinc finger protein 230 |
| ZNF552 | zinc finger protein 552 |
| ZNF750 | zinc finger protein 750 |