ethisterone-3864 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the ethisterone-3864 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
AHSP alpha hemoglobin stabilizing protein
AKAP5 A kinase (PRKA) anchor protein 5
ALDOB aldolase B, fructose-bisphosphate
ALOX5 arachidonate 5-lipoxygenase
ARC activity-regulated cytoskeleton-associated protein
ARHGAP26 Rho GTPase activating protein 26
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATAT1 alpha tubulin acetyltransferase 1
BDKRB2 bradykinin receptor B2
BHMT betaine--homocysteine S-methyltransferase
BMP1 bone morphogenetic protein 1
C17ORF53 chromosome 17 open reading frame 53
CASP4 caspase 4, apoptosis-related cysteine peptidase
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
COL1A1 collagen, type I, alpha 1
COL8A2 collagen, type VIII, alpha 2
CRY2 cryptochrome circadian clock 2
CSDC2 cold shock domain containing C2, RNA binding
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen)
DLC1 DLC1 Rho GTPase activating protein
DUX1 double homeobox 1
EGR1 early growth response 1
EN2 engrailed homeobox 2
EPHB2 EPH receptor B2
ETV1 ets variant 1
FAM106A family with sequence similarity 106, member A
FAM49B family with sequence similarity 49, member B
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FLJ11292
FN1 fibronectin 1
FXYD7 FXYD domain containing ion transport regulator 7
GAST gastrin
GPER1 G protein-coupled estrogen receptor 1
GPR15 G protein-coupled receptor 15
GPR31 G protein-coupled receptor 31
HCG4 HLA complex group 4 (non-protein coding)
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXD1 homeobox D1
HPX hemopexin
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
IFT27 intraflagellar transport 27
IL13 interleukin 13
IL2RB interleukin 2 receptor, beta
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNK5 potassium channel, two pore domain subfamily K, member 5
KLK13 kallikrein-related peptidase 13
LINC00216 long intergenic non-protein coding RNA 216
LLGL1 lethal giant larvae homolog 1 (Drosophila)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MCAM melanoma cell adhesion molecule
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MXD1 MAX dimerization protein 1
NAT6 N-acetyltransferase 6 (GCN5-related)
NPFFR1 neuropeptide FF receptor 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NYNRIN NYN domain and retroviral integrase containing
OXCT2 3-oxoacid CoA transferase 2
PAIP2B poly(A) binding protein interacting protein 2B
PARP11 poly (ADP-ribose) polymerase family, member 11
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PGLYRP1 peptidoglycan recognition protein 1
PICK1 protein interacting with PRKCA 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLD1 phospholipase D1, phosphatidylcholine-specific
PLXNB3 plexin B3
PRAMEF12 PRAME family member 12
PTCH2 patched 2
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RAP1GAP RAP1 GTPase activating protein
RPL35A ribosomal protein L35a
RRBP1 ribosome binding protein 1
RUNX1 runt-related transcription factor 1
SAG S-antigen; retina and pineal gland (arrestin)
SEC14L2 SEC14-like 2 (S. cerevisiae)
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC22A14 solute carrier family 22, member 14
SLC22A17 solute carrier family 22, member 17
SNAP25 synaptosomal-associated protein, 25kDa
SNCG synuclein, gamma (breast cancer-specific protein 1)
SPTB spectrin, beta, erythrocytic
SRCAP Snf2-related CREBBP activator protein
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
SULT4A1 sulfotransferase family 4A, member 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
TAPT1 transmembrane anterior posterior transformation 1
TBXA2R thromboxane A2 receptor
TICAM1 toll-like receptor adaptor molecule 1
TMCC2 transmembrane and coiled-coil domain family 2
TMOD2 tropomodulin 2 (neuronal)
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TP73-AS1 TP73 antisense RNA 1
TRAPPC9 trafficking protein particle complex 9
WNT16 wingless-type MMTV integration site family, member 16
ZBTB7A zinc finger and BTB domain containing 7A

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AFAP1 actin filament associated protein 1
AHNAK2 AHNAK nucleoprotein 2
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANKFY1 ankyrin repeat and FYVE domain containing 1
AP1AR adaptor-related protein complex 1 associated regulatory protein
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARMCX2 armadillo repeat containing, X-linked 2
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ARRB1 arrestin, beta 1
BAG4 BCL2-associated athanogene 4
C17ORF80 chromosome 17 open reading frame 80
CCDC85C coiled-coil domain containing 85C
CHRM3 cholinergic receptor, muscarinic 3
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CSAD cysteine sulfinic acid decarboxylase
CUEDC1 CUE domain containing 1
CXADR coxsackie virus and adenovirus receptor
CYB5R1 cytochrome b5 reductase 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DBR1 debranching RNA lariats 1
DEPDC1 DEP domain containing 1
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DNAL4 dynein, axonemal, light chain 4
DVL1 dishevelled segment polarity protein 1
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative)
EPHA4 EPH receptor A4
EPN3 epsin 3
ERCC4 excision repair cross-complementation group 4
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM193A family with sequence similarity 193, member A
FAM198B family with sequence similarity 198, member B
FBXL6 F-box and leucine-rich repeat protein 6
FCHSD2 FCH and double SH3 domains 2
FRS2 fibroblast growth factor receptor substrate 2
GLMN glomulin, FKBP associated protein
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPATCH3 G patch domain containing 3
GPR27 G protein-coupled receptor 27
GPRASP1 G protein-coupled receptor associated sorting protein 1
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
GTF2I general transcription factor IIi
HIST1H4C histone cluster 1, H4c
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
KLHL21 kelch-like family member 21
LAMA3 laminin, alpha 3
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MBOAT2 membrane bound O-acyltransferase domain containing 2
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYO1D myosin ID
NAV2 neuron navigator 2
NDE1 nudE neurodevelopment protein 1
NPIPB3 nuclear pore complex interacting protein family, member B3
NPM3 nucleophosmin/nucleoplasmin 3
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
NXPH4 neurexophilin 4
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
PPP6R3 protein phosphatase 6, regulatory subunit 3
RAB30 RAB30, member RAS oncogene family
RIPPLY3 ripply transcriptional repressor 3
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF113A ring finger protein 113A
RNF25 ring finger protein 25
RP2 retinitis pigmentosa 2 (X-linked recessive)
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
RUFY1 RUN and FYVE domain containing 1
SCRN3 secernin 3
SCYL2 SCY1-like 2 (S. cerevisiae)
SHROOM2 shroom family member 2
SND1 staphylococcal nuclease and tudor domain containing 1
SNX27 sorting nexin family member 27
SOAT1 sterol O-acyltransferase 1
STON1 stonin 1
TAOK1 TAO kinase 1
TCTA T-cell leukemia translocation altered
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TMEM184C transmembrane protein 184C
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRIM25 tripartite motif containing 25
UNC119 unc-119 homolog (C. elegans)
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
USP32 ubiquitin specific peptidase 32
VASP vasodilator-stimulated phosphoprotein
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial
ZBTB38 zinc finger and BTB domain containing 38
ZBTB6 zinc finger and BTB domain containing 6
ZCCHC2 zinc finger, CCHC domain containing 2
ZNF282 zinc finger protein 282
ZNF329 zinc finger protein 329
ZNF480 zinc finger protein 480
ZW10 zw10 kinetochore protein