| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the ethosuximide-1433 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALPK1 | alpha-kinase 1 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| ARHGAP33 | Rho GTPase activating protein 33 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| BMP7 | bone morphogenetic protein 7 |
| BNIP1 | BCL2/adenovirus E1B 19kDa interacting protein 1 |
| BRAP | BRCA1 associated protein |
| C19ORF66 | chromosome 19 open reading frame 66 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| CA6 | carbonic anhydrase VI |
| CD2BP2 | CD2 (cytoplasmic tail) binding protein 2 |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CFAP45 | cilia and flagella associated protein 45 |
| CHRNA4 | cholinergic receptor, nicotinic, alpha 4 (neuronal) |
| CREB3 | cAMP responsive element binding protein 3 |
| CYHR1 | cysteine/histidine-rich 1 |
| DCTN5 | dynactin 5 (p25) |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) |
| DOC2B | double C2-like domains, beta |
| DUS2 | dihydrouridine synthase 2 |
| EHD1 | EH-domain containing 1 |
| EHMT2 | euchromatic histone-lysine N-methyltransferase 2 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| FAM63A | family with sequence similarity 63, member A |
| FMNL1 | formin-like 1 |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| GANAB | glucosidase, alpha; neutral AB |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GPR12 | G protein-coupled receptor 12 |
| GPR4 | G protein-coupled receptor 4 |
| HEMK1 | HemK methyltransferase family member 1 |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFITM3 | interferon induced transmembrane protein 3 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| ITSN1 | intersectin 1 (SH3 domain protein) |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KLHL36 | kelch-like family member 36 |
| LENEP | lens epithelial protein |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| MAPKAPK5-AS1 | MAPKAPK5 antisense RNA 1 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MDC1 | mediator of DNA-damage checkpoint 1 |
| MECP2 | methyl CpG binding protein 2 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase |
| MMP19 | matrix metallopeptidase 19 |
| MTF1 | metal-regulatory transcription factor 1 |
| NBEAL2 | neurobeachin-like 2 |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PHF20 | PHD finger protein 20 |
| PIDD1 | p53-induced death domain protein 1 |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PPP1R7 | protein phosphatase 1, regulatory subunit 7 |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PRKD2 | protein kinase D2 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RANBP17 | RAN binding protein 17 |
| RHBDD3 | rhomboid domain containing 3 |
| RNASE3 | ribonuclease, RNase A family, 3 |
| RSG1 | REM2 and RAB-like small GTPase 1 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SEC31B | SEC31 homolog B (S. cerevisiae) |
| SETX | senataxin |
| SFTPB | surfactant protein B |
| SLC10A2 | solute carrier family 10 (sodium/bile acid cotransporter), member 2 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SLC5A1 | solute carrier family 5 (sodium/glucose cotransporter), member 1 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SPPL2B | signal peptide peptidase like 2B |
| STX2 | syntaxin 2 |
| SYMPK | symplekin |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| TBC1D22A | TBC1 domain family, member 22A |
| TBCD | tubulin folding cofactor D |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TMEM63A | transmembrane protein 63A |
| TREX1 | three prime repair exonuclease 1 |
| TSC2 | tuberous sclerosis 2 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| TUBB3 | tubulin, beta 3 class III |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| VARS | valyl-tRNA synthetase |
| VCX2 | variable charge, X-linked 2 |
| WDR13 | WD repeat domain 13 |
| ZFHX4 | zinc finger homeobox 4 |
| ZNF609 | zinc finger protein 609 |
| ZNF668 | zinc finger protein 668 |
| ZSCAN32 | zinc finger and SCAN domain containing 32 |
| ZSWIM8 | zinc finger, SWIM-type containing 8 |
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain |
| ACTL6A | actin-like 6A |
| ADAM9 | ADAM metallopeptidase domain 9 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein |
| ARMT1 | acidic residue methyltransferase 1 |
| ATF1 | activating transcription factor 1 |
| ATP5J | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| ATXN2 | ataxin 2 |
| AZI2 | 5-azacytidine induced 2 |
| C5ORF28 | chromosome 5 open reading frame 28 |
| CD302 | CD302 molecule |
| CDC73 | cell division cycle 73 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CENPQ | centromere protein Q |
| CEP170 | centrosomal protein 170kDa |
| CHUK | conserved helix-loop-helix ubiquitous kinase |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit |
| CNIH1 | cornichon family AMPA receptor auxiliary protein 1 |
| CPOX | coproporphyrinogen oxidase |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa |
| CYCS | cytochrome c, somatic |
| DBF4 | DBF4 zinc finger |
| DCK | deoxycytidine kinase |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DPYD | dihydropyrimidine dehydrogenase |
| EIF1B | eukaryotic translation initiation factor 1B |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 |
| FANCL | Fanconi anemia, complementation group L |
| FASTKD3 | FAST kinase domains 3 |
| FBXO5 | F-box protein 5 |
| FUBP3 | far upstream element (FUSE) binding protein 3 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) |
| GPN3 | GPN-loop GTPase 3 |
| HMGB2 | high mobility group box 2 |
| HMGN3 | high mobility group nucleosomal binding domain 3 |
| IMPACT | impact RWD domain protein |
| JMJD1C | jumonji domain containing 1C |
| KIF20B | kinesin family member 20B |
| LOC100129361 | |
| LYRM2 | LYR motif containing 2 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MEX3C | mex-3 RNA binding family member C |
| MFF | mitochondrial fission factor |
| MORC3 | MORC family CW-type zinc finger 3 |
| MRPL19 | mitochondrial ribosomal protein L19 |
| MRPL33 | mitochondrial ribosomal protein L33 |
| MYL12B | myosin, light chain 12B, regulatory |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| NECAP1 | NECAP endocytosis associated 1 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 |
| NRBF2 | nuclear receptor binding factor 2 |
| NUCB2 | nucleobindin 2 |
| OSTM1 | osteopetrosis associated transmembrane protein 1 |
| PCNP | PEST proteolytic signal containing nuclear protein |
| PIBF1 | progesterone immunomodulatory binding factor 1 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| RACGAP1 | Rac GTPase activating protein 1 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) |
| RANBP6 | RAN binding protein 6 |
| RAP1A | RAP1A, member of RAS oncogene family |
| RBL1 | retinoblastoma-like 1 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit |
| RNF138 | ring finger protein 138, E3 ubiquitin protein ligase |
| RPS14P3 | ribosomal protein S14 pseudogene 3 |
| RPS25 | ribosomal protein S25 |
| RRN3 | RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) |
| RSL24D1 | ribosomal L24 domain containing 1 |
| RWDD3 | RWD domain containing 3 |
| SARAF | store-operated calcium entry-associated regulatory factor |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 |
| SHCBP1 | SHC SH2-domain binding protein 1 |
| SLMO2 | slowmo homolog 2 (Drosophila) |
| SMNDC1 | survival motor neuron domain containing 1 |
| STK39 | serine threonine kinase 39 |
| STXBP3 | syntaxin binding protein 3 |
| SUMO4 | small ubiquitin-like modifier 4 |
| TBPL1 | TBP-like 1 |
| TFB2M | transcription factor B2, mitochondrial |
| TGS1 | trimethylguanosine synthase 1 |
| TM9SF2 | transmembrane 9 superfamily member 2 |
| TMEM123 | transmembrane protein 123 |
| TMEM38B | transmembrane protein 38B |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) |
| TTF2 | transcription termination factor, RNA polymerase II |
| UBA3 | ubiquitin-like modifier activating enzyme 3 |
| UBQLN2 | ubiquilin 2 |
| UTP11L | UTP11-like, U3 small nucleolar ribonucleoprotein (yeast) |
| VRK2 | vaccinia related kinase 2 |
| WASF1 | WAS protein family, member 1 |
| WDR11 | WD repeat domain 11 |
| ZCCHC8 | zinc finger, CCHC domain containing 8 |
| ZNF217 | zinc finger protein 217 |
