| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the ethosuximide-2116 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD8 | abhydrolase domain containing 8 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ANXA10 | annexin A10 |
| ARHGAP33 | Rho GTPase activating protein 33 |
| ARSB | arylsulfatase B |
| AURKA | aurora kinase A |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BTBD7 | BTB (POZ) domain containing 7 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C1QL1 | complement component 1, q subcomponent-like 1 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CACYBP | calcyclin binding protein |
| CALD1 | caldesmon 1 |
| CFAP45 | cilia and flagella associated protein 45 |
| CFAP69 | cilia and flagella associated protein 69 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| COL9A2 | collagen, type IX, alpha 2 |
| CREB5 | cAMP responsive element binding protein 5 |
| CREBZF | CREB/ATF bZIP transcription factor |
| DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DNAAF1 | dynein, axonemal, assembly factor 1 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| EGFL7 | EGF-like-domain, multiple 7 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| ETV1 | ets variant 1 |
| EXOC7 | exocyst complex component 7 |
| EZH1 | enhancer of zeste 1 polycomb repressive complex 2 subunit |
| FAM174B | family with sequence similarity 174, member B |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FNDC4 | fibronectin type III domain containing 4 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GLB1L | galactosidase, beta 1-like |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| HIST1H3G | histone cluster 1, H3g |
| HOOK1 | hook microtubule-tethering protein 1 |
| HR | hair growth associated |
| IGHMBP2 | immunoglobulin mu binding protein 2 |
| IGL | immunoglobulin lambda locus |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KDM4B | lysine (K)-specific demethylase 4B |
| KDM6B | lysine (K)-specific demethylase 6B |
| LDB1 | LIM domain binding 1 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LRP1 | low density lipoprotein receptor-related protein 1 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP3K12 | mitogen-activated protein kinase kinase kinase 12 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MEF2D | myocyte enhancer factor 2D |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MTSS1L | metastasis suppressor 1-like |
| MVD | mevalonate (diphospho) decarboxylase |
| NOP16 | NOP16 nucleolar protein |
| NPR1 | natriuretic peptide receptor 1 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
| NTF3 | neurotrophin 3 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PROZ | protein Z, vitamin K-dependent plasma glycoprotein |
| PRR14L | proline rich 14-like |
| PRR4 | proline rich 4 (lacrimal) |
| RAB36 | RAB36, member RAS oncogene family |
| REST | RE1-silencing transcription factor |
| RIN3 | Ras and Rab interactor 3 |
| RNF122 | ring finger protein 122 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RWDD2A | RWD domain containing 2A |
| SC5D | sterol-C5-desaturase |
| SIRT6 | sirtuin 6 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| SUGP1 | SURP and G patch domain containing 1 |
| TEX14 | testis expressed 14 |
| TLE2 | transducin-like enhancer of split 2 |
| TRIM29 | tripartite motif containing 29 |
| TTC9 | tetratricopeptide repeat domain 9 |
| UCP1 | uncoupling protein 1 (mitochondrial, proton carrier) |
| VAV3 | vav 3 guanine nucleotide exchange factor |
| YTHDC1 | YTH domain containing 1 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF423 | zinc finger protein 423 |
| ZNF442 | zinc finger protein 442 |
| ZNF444 | zinc finger protein 444 |
| Symbol | Name |
|---|---|
| AEN | apoptosis enhancing nuclease |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARRB2 | arrestin, beta 2 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BCAS4 | breast carcinoma amplified sequence 4 |
| BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C1ORF112 | chromosome 1 open reading frame 112 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| CCDC176 | coiled-coil domain containing 176 |
| CCDC85C | coiled-coil domain containing 85C |
| CD70 | CD70 molecule |
| CDKN2AIP | CDKN2A interacting protein |
| CEP112 | centrosomal protein 112kDa |
| CEP131 | centrosomal protein 131kDa |
| COBL | cordon-bleu WH2 repeat protein |
| CORO1A | coronin, actin binding protein, 1A |
| DBR1 | debranching RNA lariats 1 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| EFNA3 | ephrin-A3 |
| ELP4 | elongator acetyltransferase complex subunit 4 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 |
| ERF | Ets2 repressor factor |
| EVPL | envoplakin |
| EXOSC5 | exosome component 5 |
| FGGY | FGGY carbohydrate kinase domain containing |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| GPR39 | G protein-coupled receptor 39 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HYI | hydroxypyruvate isomerase (putative) |
| IL17RA | interleukin 17 receptor A |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| IREB2 | iron-responsive element binding protein 2 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| LRRC61 | leucine rich repeat containing 61 |
| MCMBP | minichromosome maintenance complex binding protein |
| MON1B | MON1 secretory trafficking family member B |
| MRPL17 | mitochondrial ribosomal protein L17 |
| MSL2 | male-specific lethal 2 homolog (Drosophila) |
| NDRG4 | NDRG family member 4 |
| NDUFA7 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NECAP2 | NECAP endocytosis associated 2 |
| NID2 | nidogen 2 (osteonidogen) |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| OSMR | oncostatin M receptor |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 |
| PEX13 | peroxisomal biogenesis factor 13 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| PPWD1 | peptidylprolyl isomerase domain and WD repeat containing 1 |
| PRR15L | proline rich 15-like |
| PRRC1 | proline-rich coiled-coil 1 |
| PSAT1 | phosphoserine aminotransferase 1 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RANBP17 | RAN binding protein 17 |
| RIC8B | RIC8 guanine nucleotide exchange factor B |
| RNF146 | ring finger protein 146 |
| RRN3 | RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) |
| SAMD9 | sterile alpha motif domain containing 9 |
| SDCCAG3 | serologically defined colon cancer antigen 3 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SLC41A3 | solute carrier family 41, member 3 |
| SMG9 | SMG9 nonsense mediated mRNA decay factor |
| SNX10 | sorting nexin 10 |
| ST5 | suppression of tumorigenicity 5 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| THOC1 | THO complex 1 |
| TLN1 | talin 1 |
| TRIM52 | tripartite motif containing 52 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| UBN1 | ubinuclein 1 |
| UBQLN4 | ubiquilin 4 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| WNT7A | wingless-type MMTV integration site family, member 7A |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF134 | zinc finger protein 134 |
| ZNF254 | zinc finger protein 254 |
| ZNF34 | zinc finger protein 34 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZSCAN5A | zinc finger and SCAN domain containing 5A |
