| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the ethosuximide-2280 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACPP | acid phosphatase, prostate |
| ACSBG2 | acyl-CoA synthetase bubblegum family member 2 |
| ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif, 7 |
| ALK | anaplastic lymphoma receptor tyrosine kinase |
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 |
| ATP10A | ATPase, class V, type 10A |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| BIRC7 | baculoviral IAP repeat containing 7 |
| BLNK | B-cell linker |
| C2ORF72 | chromosome 2 open reading frame 72 |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CCL19 | chemokine (C-C motif) ligand 19 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLEC4A | C-type lectin domain family 4, member A |
| CLEC4E | C-type lectin domain family 4, member E |
| COL10A1 | collagen, type X, alpha 1 |
| COMP | cartilage oligomeric matrix protein |
| COPG2IT1 | COPG2 imprinted transcript 1 (non-protein coding) |
| CPSF1 | cleavage and polyadenylation specific factor 1, 160kDa |
| CRYGD | crystallin, gamma D |
| CSF1R | colony stimulating factor 1 receptor |
| CTIF | CBP80/20-dependent translation initiation factor |
| DIO2 | deiodinase, iodothyronine, type II |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) |
| FPR1 | formyl peptide receptor 1 |
| FRMD1 | FERM domain containing 1 |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| GJD2 | gap junction protein, delta 2, 36kDa |
| GLIPR1 | GLI pathogenesis-related 1 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| H2AFX | H2A histone family, member X |
| HAP1 | huntingtin-associated protein 1 |
| HCFC1 | host cell factor C1 |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| HHLA1 | HERV-H LTR-associating 1 |
| HIPK2 | homeodomain interacting protein kinase 2 |
| HIST1H4D | histone cluster 1, H4d |
| HOXA10 | homeobox A10 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IGSF6 | immunoglobulin superfamily, member 6 |
| IL2RB | interleukin 2 receptor, beta |
| INO80D | INO80 complex subunit D |
| IQCA1 | IQ motif containing with AAA domain 1 |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| LDB3 | LIM domain binding 3 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MINK1 | misshapen-like kinase 1 |
| MMP19 | matrix metallopeptidase 19 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MSR1 | macrophage scavenger receptor 1 |
| MTL5 | metallothionein-like 5, testis-specific (tesmin) |
| NEU3 | sialidase 3 (membrane sialidase) |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PDGFD | platelet derived growth factor D |
| PGLYRP4 | peptidoglycan recognition protein 4 |
| PLCB2 | phospholipase C, beta 2 |
| PLK3 | polo-like kinase 3 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RAPSN | receptor-associated protein of the synapse |
| RGS9 | regulator of G-protein signaling 9 |
| RIMS1 | regulating synaptic membrane exocytosis 1 |
| RND2 | Rho family GTPase 2 |
| RNF144A | ring finger protein 144A |
| RUNX1 | runt-related transcription factor 1 |
| RUNX2 | runt-related transcription factor 2 |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPTA1 | spectrin, alpha, erythrocytic 1 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TF | transferrin |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TPMT | thiopurine S-methyltransferase |
| UTRN | utrophin |
| WSCD1 | WSC domain containing 1 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALPK1 | alpha-kinase 1 |
| ARC | activity-regulated cytoskeleton-associated protein |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C3 | complement component 3 |
| CAPN15 | calpain 15 |
| CCDC132 | coiled-coil domain containing 132 |
| CCDC134 | coiled-coil domain containing 134 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CD80 | CD80 molecule |
| CDK18 | cyclin-dependent kinase 18 |
| CDK3 | cyclin-dependent kinase 3 |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CHST10 | carbohydrate sulfotransferase 10 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CXXC4 | CXXC finger protein 4 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| DIXDC1 | DIX domain containing 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNM3 | dynamin 3 |
| DUSP2 | dual specificity phosphatase 2 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| FAM76A | family with sequence similarity 76, member A |
| FLCN | folliculin |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FLT4 | fms-related tyrosine kinase 4 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC11 | histone deacetylase 11 |
| HIST1H2BM | histone cluster 1, H2bm |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IREB2 | iron-responsive element binding protein 2 |
| ITGA10 | integrin, alpha 10 |
| KITLG | KIT ligand |
| KLHDC8A | kelch domain containing 8A |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAL | mal, T-cell differentiation protein |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NIPAL2 | NIPA-like domain containing 2 |
| OLFML2A | olfactomedin-like 2A |
| OTUD3 | OTU deubiquitinase 3 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PEX26 | peroxisomal biogenesis factor 26 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 |
| PITX2 | paired-like homeodomain 2 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PODXL2 | podocalyxin-like 2 |
| POLL | polymerase (DNA directed), lambda |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PRSS16 | protease, serine, 16 (thymus) |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RASL11B | RAS-like, family 11, member B |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RNF121 | ring finger protein 121 |
| RNF122 | ring finger protein 122 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RNF43 | ring finger protein 43 |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLN | sarcolipin |
| SLPI | secretory leukocyte peptidase inhibitor |
| SNTA1 | syntrophin, alpha 1 |
| STX1A | syntaxin 1A (brain) |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYBU | syntabulin (syntaxin-interacting) |
| TARP | TCR gamma alternate reading frame protein |
| TBC1D17 | TBC1 domain family, member 17 |
| TBC1D2 | TBC1 domain family, member 2 |
| TBKBP1 | TBK1 binding protein 1 |
| TET3 | tet methylcytosine dioxygenase 3 |
| THBS3 | thrombospondin 3 |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| TSGA10 | testis specific, 10 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| YY2 | YY2 transcription factor |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF76 | zinc finger protein 76 |
| ZNF778 | zinc finger protein 778 |
