ethosuximide Gene Set
Genes
27 genes differentially expressed following the ethosuximide small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
FGF4
|
fibroblast growth factor 4
|
5.13448
|
|
PLSCR1
|
phospholipid scramblase 1
|
3.47452
|
|
SEMA3C
|
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
|
3.40118
|
|
SUV39H1
|
suppressor of variegation 3-9 homolog 1 (Drosophila)
|
3.32348
|
|
PTGER3
|
prostaglandin E receptor 3 (subtype EP3)
|
3.30229
|
|
OR12D3
|
olfactory receptor, family 12, subfamily D, member 3
|
3.13649
|
|
PPP3CB
|
protein phosphatase 3, catalytic subunit, beta isozyme
|
3.05777
|
|
STARD7
|
StAR-related lipid transfer (START) domain containing 7
|
3.05163
|
|
PRKCQ
|
protein kinase C, theta
|
3.04416
|
|
IFNA21
|
interferon, alpha 21
|
3.04298
|
|
DUSP2
|
dual specificity phosphatase 2
|
3.02838
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-5.27341
|
|
DNAJC1
|
DnaJ (Hsp40) homolog, subfamily C, member 1
|
-3.9116
|
|
NFKBIB
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
|
-3.87904
|
|
RBM34
|
RNA binding motif protein 34
|
-3.63104
|
|
GOLT1B
|
golgi transport 1B
|
-3.61122
|
|
MAP7
|
microtubule-associated protein 7
|
-3.32649
|
|
DEGS1
|
delta(4)-desaturase, sphingolipid 1
|
-3.21008
|
|
VSIG4
|
V-set and immunoglobulin domain containing 4
|
-3.18049
|
|
NAE1
|
NEDD8 activating enzyme E1 subunit 1
|
-3.16712
|
|
IRGC
|
immunity-related GTPase family, cinema
|
-3.15043
|
|
GGPS1
|
geranylgeranyl diphosphate synthase 1
|
-3.14241
|
|
ECH1
|
enoyl CoA hydratase 1, peroxisomal
|
-3.13538
|
|
OAZ3
|
ornithine decarboxylase antizyme 3
|
-3.09835
|
|
MS4A4A
|
membrane-spanning 4-domains, subfamily A, member 4A
|
-3.07885
|
|
TDRD7
|
tudor domain containing 7
|
-3.06962
|
|
TBP
|
TATA box binding protein
|
-3.01839
|
