ethotoin-2196 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

199 genes differentially expressed following the ethotoin-2196 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRE1 adhesion G protein-coupled receptor E1
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APOL2 apolipoprotein L, 2
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARMC9 armadillo repeat containing 9
BMP15 bone morphogenetic protein 15
C6ORF10 chromosome 6 open reading frame 10
CCDC85B coiled-coil domain containing 85B
CD24 CD24 molecule
CD6 CD6 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CHPF chondroitin polymerizing factor
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CLPS colipase, pancreatic
CLTA clathrin, light chain A
CYLD cylindromatosis (turban tumor syndrome)
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
DCSTAMP dendrocyte expressed seven transmembrane protein
DOCK6 dedicator of cytokinesis 6
DSG3 desmoglein 3
EDDM3B epididymal protein 3B
EPHB2 EPH receptor B2
FLT1 fms-related tyrosine kinase 1
GBP1 guanylate binding protein 1, interferon-inducible
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IFITM1 interferon induced transmembrane protein 1
IGHM immunoglobulin heavy constant mu
IGHMBP2 immunoglobulin mu binding protein 2
IQCG IQ motif containing G
IRF6 interferon regulatory factor 6
ISG20 interferon stimulated exonuclease gene 20kDa
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2
KDM8 lysine (K)-specific demethylase 8
KLK13 kallikrein-related peptidase 13
KRT75 keratin 75, type II
LAMB4 laminin, beta 4
LAMP3 lysosomal-associated membrane protein 3
LIME1 Lck interacting transmembrane adaptor 1
LMF1 lipase maturation factor 1
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MNMIP1 manchette microtubule inner protein 1
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
NPPA natriuretic peptide A
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NTM neurotrimin
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OXCT2 3-oxoacid CoA transferase 2
PADI1 peptidyl arginine deiminase, type I
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDLIM5 PDZ and LIM domain 5
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PGAP3 post-GPI attachment to proteins 3
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCL2 phospholipase C-like 2
PLSCR3 phospholipid scramblase 3
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCI protein kinase C, iota
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBMS2 RNA binding motif, single stranded interacting protein 2
RCAN2 regulator of calcineurin 2
RPL13P5 ribosomal protein L13 pseudogene 5
RPL18 ribosomal protein L18
S100B S100 calcium binding protein B
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLAMF7 SLAM family member 7
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC12A8 solute carrier family 12, member 8
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SORBS3 sorbin and SH3 domain containing 3
SPTB spectrin, beta, erythrocytic
SSX1 synovial sarcoma, X breakpoint 1
ST20 suppressor of tumorigenicity 20
SV2B synaptic vesicle glycoprotein 2B
SYN2 synapsin II
TAOK2 TAO kinase 2
TBL1Y transducin (beta)-like 1, Y-linked
TBX10 T-box 10
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TK2 thymidine kinase 2, mitochondrial
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TNS1 tensin 1
TRGV5 T cell receptor gamma variable 5
TRIM3 tripartite motif containing 3
TSKU tsukushi, small leucine rich proteoglycan
WDR1 WD repeat domain 1
ZC3H7B zinc finger CCCH-type containing 7B
ZNF518A zinc finger protein 518A
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACOX2 acyl-CoA oxidase 2, branched chain
AGPS alkylglycerone phosphate synthase
APH1B APH1B gamma secretase subunit
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOLD1 apolipoprotein L domain containing 1
BAX BCL2-associated X protein
BCL2L2 BCL2-like 2
BTD biotinidase
C12ORF49 chromosome 12 open reading frame 49
C17ORF53 chromosome 17 open reading frame 53
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAPN15 calpain 15
CDA cytidine deaminase
CDR2L cerebellar degeneration-related protein 2-like
CES3 carboxylesterase 3
CFP complement factor properdin
CHST10 carbohydrate sulfotransferase 10
CORO7 coronin 7
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
CXORF56 chromosome X open reading frame 56
DCAF13 DDB1 and CUL4 associated factor 13
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DEPDC5 DEP domain containing 5
DHODH dihydroorotate dehydrogenase (quinone)
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11
EMILIN2 elastin microfibril interfacer 2
ERCC2 excision repair cross-complementation group 2
ERN2 endoplasmic reticulum to nucleus signaling 2
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXN2 forkhead box N2
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GID4 GID complex subunit 4
GPHN gephyrin
GTF2I general transcription factor IIi
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
INCENP inner centromere protein antigens 135/155kDa
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA1024 KIAA1024
LIG4 ligase IV, DNA, ATP-dependent
LMNB1 lamin B1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MDM4 MDM4, p53 regulator
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
METRN meteorin, glial cell differentiation regulator
MTERF4 mitochondrial transcription termination factor 4
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NDE1 nudE neurodevelopment protein 1
NPM3 nucleophosmin/nucleoplasmin 3
NUBPL nucleotide binding protein-like
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
NXPE3 neurexophilin and PC-esterase domain family, member 3
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PADI2 peptidyl arginine deiminase, type II
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PCCB propionyl CoA carboxylase, beta polypeptide
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRR7 proline rich 7 (synaptic)
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF122 ring finger protein 122
RNH1 ribonuclease/angiogenin inhibitor 1
SCYL2 SCY1-like 2 (S. cerevisiae)
SENP7 SUMO1/sentrin specific peptidase 7
SERGEF secretion regulating guanine nucleotide exchange factor
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SETD1A SET domain containing 1A
SGPP1 sphingosine-1-phosphate phosphatase 1
SIDT1 SID1 transmembrane family, member 1
SLC25A40 solute carrier family 25, member 40
SPATA2L spermatogenesis associated 2-like
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SRR serine racemase
STX11 syntaxin 11
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TCTN1 tectonic family member 1
TGFBR1 transforming growth factor, beta receptor 1
TIAM2 T-cell lymphoma invasion and metastasis 2
TKFC triokinase/FMN cyclase
TMEM230 transmembrane protein 230
TPM3 tropomyosin 3
TRIM25 tripartite motif containing 25
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TTC26 tetratricopeptide repeat domain 26
TWISTNB TWIST neighbor
UNC93B1 unc-93 homolog B1 (C. elegans)
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZBTB25 zinc finger and BTB domain containing 25
ZC4H2 zinc finger, C4H2 domain containing
ZDHHC14 zinc finger, DHHC-type containing 14
ZHX2 zinc fingers and homeoboxes 2
ZNF225 zinc finger protein 225
ZNF324 zinc finger protein 324
ZNF480 zinc finger protein 480
ZW10 zw10 kinetochore protein