ethotoin-3809 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the ethotoin-3809 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABI2 abl-interactor 2
ACACB acetyl-CoA carboxylase beta
ACOT11 acyl-CoA thioesterase 11
ADGRB2 adhesion G protein-coupled receptor B2
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALOX5 arachidonate 5-lipoxygenase
ANGPTL2 angiopoietin-like 2
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ATAT1 alpha tubulin acetyltransferase 1
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C10ORF12 chromosome 10 open reading frame 12
C22ORF46 chromosome 22 open reading frame 46
CD53 CD53 molecule
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLDN9 claudin 9
COL15A1 collagen, type XV, alpha 1
CRISP2 cysteine-rich secretory protein 2
CROCCP3 ciliary rootlet coiled-coil, rootletin pseudogene 3
CRYGC crystallin, gamma C
CTBP2 C-terminal binding protein 2
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22
DGCR8 DGCR8 microprocessor complex subunit
DTNB dystrobrevin, beta
EMILIN2 elastin microfibril interfacer 2
ERC2 ELKS/RAB6-interacting/CAST family member 2
FHL3 four and a half LIM domains 3
FKBP10 FK506 binding protein 10, 65 kDa
FLT1 fms-related tyrosine kinase 1
GAS7 growth arrest-specific 7
GATA1 GATA binding protein 1 (globin transcription factor 1)
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GOLGA2P5 golgin A2 pseudogene 5
GPR85 G protein-coupled receptor 85
GSTA1 glutathione S-transferase alpha 1
HEXIM1 hexamethylene bis-acetamide inducible 1
HIST1H1T histone cluster 1, H1t
HIST1H3I histone cluster 1, H3i
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HOXD9 homeobox D9
IL37 interleukin 37
INPP5J inositol polyphosphate-5-phosphatase J
INSR insulin receptor
IRF4 interferon regulatory factor 4
LAMA4 laminin, alpha 4
LCAT lecithin-cholesterol acyltransferase
MAP2K7 mitogen-activated protein kinase kinase 7
MED25 mediator complex subunit 25
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MMP25 matrix metallopeptidase 25
MYOZ2 myozenin 2
MYT1 myelin transcription factor 1
NEB nebulin
NKG7 natural killer cell granule protein 7
NOVA2 neuro-oncological ventral antigen 2
NPY2R neuropeptide Y receptor Y2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OR2F2 olfactory receptor, family 2, subfamily F, member 2
OTOR otoraplin
PCDHGA1 protocadherin gamma subfamily A, 1
PDE4A phosphodiesterase 4A, cAMP-specific
PDE4DIP phosphodiesterase 4D interacting protein
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PGM5 phosphoglucomutase 5
PHC3 polyhomeotic homolog 3 (Drosophila)
PKNOX2 PBX/knotted 1 homeobox 2
PLCH2 phospholipase C, eta 2
PLCL2 phospholipase C-like 2
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PLP1 proteolipid protein 1
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RASAL2 RAS protein activator like 2
RETN resistin
RGCC regulator of cell cycle
SIRPA signal-regulatory protein alpha
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SMAD5-AS1 SMAD5 antisense RNA 1
SOX2 SRY (sex determining region Y)-box 2
SSTR5 somatostatin receptor 5
TDRD12 tudor domain containing 12
TIAM2 T-cell lymphoma invasion and metastasis 2
TMEM176A transmembrane protein 176A
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TP53I11 tumor protein p53 inducible protein 11
TRAPPC9 trafficking protein particle complex 9
ZBTB17 zinc finger and BTB domain containing 17
ZMAT4 zinc finger, matrin-type 4
ZNF407 zinc finger protein 407
ZNF484 zinc finger protein 484

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
AGMAT agmatine ureohydrolase (agmatinase)
AKAP5 A kinase (PRKA) anchor protein 5
AMT aminomethyltransferase
ANXA2P1 annexin A2 pseudogene 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
BCHE butyrylcholinesterase
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BET1L Bet1 golgi vesicular membrane trafficking protein-like
C1ORF105 chromosome 1 open reading frame 105
C1ORF56 chromosome 1 open reading frame 56
CA11 carbonic anhydrase XI
CBS cystathionine-beta-synthase
CCDC106 coiled-coil domain containing 106
CCNJL cyclin J-like
CCNO cyclin O
CCP110 centriolar coiled coil protein 110kDa
CD82 CD82 molecule
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CLDN8 claudin 8
CLEC4E C-type lectin domain family 4, member E
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COL9A2 collagen, type IX, alpha 2
CORO2B coronin, actin binding protein, 2B
CPZ carboxypeptidase Z
DLK2 delta-like 2 homolog (Drosophila)
DUSP2 dual specificity phosphatase 2
EDIL3 EGF-like repeats and discoidin I-like domains 3
EGFL7 EGF-like-domain, multiple 7
EML4 echinoderm microtubule associated protein like 4
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGD1 FYVE, RhoGEF and PH domain containing 1
FLJ21369 uncharacterized protein FLJ21369
FSHB follicle stimulating hormone, beta polypeptide
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLB1L galactosidase, beta 1-like
GPR3 G protein-coupled receptor 3
GRB7 growth factor receptor-bound protein 7
H2AFJ H2A histone family, member J
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HHAT hedgehog acyltransferase
IDI2-AS1 IDI2 antisense RNA 1
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
ITPKA inositol-trisphosphate 3-kinase A
KIFC3 kinesin family member C3
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLHL25 kelch-like family member 25
LINS lines homolog (Drosophila)
LRP3 low density lipoprotein receptor-related protein 3
LRP5L low density lipoprotein receptor-related protein 5-like
LYRM9 LYR motif containing 9
LZTR1 leucine-zipper-like transcription regulator 1
MAGEA12 melanoma antigen family A12
MAP2 microtubule-associated protein 2
MED23 mediator complex subunit 23
MEFV Mediterranean fever
MON1B MON1 secretory trafficking family member B
NCALD neurocalcin delta
NDNF neuron-derived neurotrophic factor
NR1H4 nuclear receptor subfamily 1, group H, member 4
NTNG1 netrin G1
NTSR1 neurotensin receptor 1 (high affinity)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PGLYRP4 peptidoglycan recognition protein 4
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PRAF2 PRA1 domain family, member 2
PRB3 proline-rich protein BstNI subfamily 3
PRSS22 protease, serine, 22
PSORS1C1 psoriasis susceptibility 1 candidate 1
QPCTL glutaminyl-peptide cyclotransferase-like
RHOBTB2 Rho-related BTB domain containing 2
ROM1 retinal outer segment membrane protein 1
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SAYSD1 SAYSVFN motif domain containing 1
SCD5 stearoyl-CoA desaturase 5
SCIN scinderin
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLMO1 slowmo homolog 1 (Drosophila)
ST7L suppression of tumorigenicity 7 like
STEAP4 STEAP family member 4
STXBP5L syntaxin binding protein 5-like
TCEAL2 transcription elongation factor A (SII)-like 2
TET3 tet methylcytosine dioxygenase 3
THOP1 thimet oligopeptidase 1
TMEM206 transmembrane protein 206
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNS2 tensin 2
TSC22D4 TSC22 domain family, member 4
TSNAXIP1 translin-associated factor X interacting protein 1
TTLL7 tubulin tyrosine ligase-like family member 7
TUBA4B tubulin, alpha 4b
XDH xanthine dehydrogenase
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF214 zinc finger protein 214
ZNF41 zinc finger protein 41
ZNF749 zinc finger protein 749
ZNF862 zinc finger protein 862