ethotoin-3892 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the ethotoin-3892 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
AGRN agrin
ALCAM activated leukocyte cell adhesion molecule
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ANO2 anoctamin 2, calcium activated chloride channel
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
B3GAT1 beta-1,3-glucuronyltransferase 1
C1QTNF1 C1q and tumor necrosis factor related protein 1
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CCL27 chemokine (C-C motif) ligand 27
CD79B CD79b molecule, immunoglobulin-associated beta
CD84 CD84 molecule
CDC14B cell division cycle 14B
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21
CLCN7 chloride channel, voltage-sensitive 7
CTSE cathepsin E
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
DOCK9 dedicator of cytokinesis 9
EDIL3 EGF-like repeats and discoidin I-like domains 3
FXYD5 FXYD domain containing ion transport regulator 5
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GAB1 GRB2-associated binding protein 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GJA8 gap junction protein, alpha 8, 50kDa
GK glycerol kinase
GPR21 G protein-coupled receptor 21
GRIK5 glutamate receptor, ionotropic, kainate 5
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C
GSTA3 glutathione S-transferase alpha 3
HKDC1 hexokinase domain containing 1
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IGHA1 immunoglobulin heavy constant alpha 1
IRF8 interferon regulatory factor 8
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KRTAP4-7 keratin associated protein 4-7
LHX1 LIM homeobox 1
LINC01587 long intergenic non-protein coding RNA 1587
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LOC100130741 uncharacterized LOC100130741
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LTK leukocyte receptor tyrosine kinase
LYZL6 lysozyme-like 6
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPK11 mitogen-activated protein kinase 11
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MMP11 matrix metallopeptidase 11
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MR1 major histocompatibility complex, class I-related
MUC2 mucin 2, oligomeric mucus/gel-forming
MYL4 myosin, light chain 4, alkali; atrial, embryonic
N4BP2L1 NEDD4 binding protein 2-like 1
NCR2 natural cytotoxicity triggering receptor 2
OCLM oculomedin
OLFML2B olfactomedin-like 2B
ONECUT1 one cut homeobox 1
OTOR otoraplin
PARP3 poly (ADP-ribose) polymerase family, member 3
PARVA parvin, alpha
PARVB parvin, beta
PAX8 paired box 8
PCDHGA3 protocadherin gamma subfamily A, 3
PKDREJ polycystin (PKD) family receptor for egg jelly
PLSCR2 phospholipid scramblase 2
PNLIPRP1 pancreatic lipase-related protein 1
PTGES prostaglandin E synthase
PTGIS prostaglandin I2 (prostacyclin) synthase
PVT1 Pvt1 oncogene (non-protein coding)
RAMP2 receptor (G protein-coupled) activity modifying protein 2
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RGS12 regulator of G-protein signaling 12
RGS4 regulator of G-protein signaling 4
RNF126P1 ring finger protein 126 pseudogene 1
RPL7 ribosomal protein L7
SIGLEC8 sialic acid binding Ig-like lectin 8
SIM2 single-minded family bHLH transcription factor 2
SIRT5 sirtuin 5
SLAMF8 SLAM family member 8
SNRK SNF related kinase
STAT2 signal transducer and activator of transcription 2, 113kDa
STMN4 stathmin-like 4
TBXA2R thromboxane A2 receptor
TCEAL2 transcription elongation factor A (SII)-like 2
TJAP1 tight junction associated protein 1 (peripheral)
TLE2 transducin-like enhancer of split 2
TMPRSS4 transmembrane protease, serine 4
TPSG1 tryptase gamma 1
TRD T cell receptor delta locus
TSHZ2 teashirt zinc finger homeobox 2
VEZT vezatin, adherens junctions transmembrane protein
WT1-AS WT1 antisense RNA
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZNF384 zinc finger protein 384

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ACSF2 acyl-CoA synthetase family member 2
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARSB arylsulfatase B
ASB8 ankyrin repeat and SOCS box containing 8
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BBS7 Bardet-Biedl syndrome 7
BIRC7 baculoviral IAP repeat containing 7
C3 complement component 3
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CALML5 calmodulin-like 5
CAMK1 calcium/calmodulin-dependent protein kinase I
CBR3 carbonyl reductase 3
CCNT1 cyclin T1
CDKL3 cyclin-dependent kinase-like 3
CENPQ centromere protein Q
CEP72 centrosomal protein 72kDa
CES3 carboxylesterase 3
CLGN calmegin
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CRABP1 cellular retinoic acid binding protein 1
CROT carnitine O-octanoyltransferase
CUL9 cullin 9
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DEAF1 DEAF1 transcription factor
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERO1L ERO1-like (S. cerevisiae)
FAM188A family with sequence similarity 188, member A
FBXO22 F-box protein 22
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GALK1 galactokinase 1
GAMT guanidinoacetate N-methyltransferase
GLB1L2 galactosidase, beta 1-like 2
GOLGA8B golgin A8 family, member B
HIST1H2AG histone cluster 1, H2ag
HMOX1 heme oxygenase 1
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IGSF1 immunoglobulin superfamily, member 1
IQCG IQ motif containing G
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF7 interferon regulatory factor 7
KLHL25 kelch-like family member 25
LINC00339 long intergenic non-protein coding RNA 339
LINS lines homolog (Drosophila)
LMO2 LIM domain only 2 (rhombotin-like 1)
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAST3 microtubule associated serine/threonine kinase 3
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MTERF1 mitochondrial transcription termination factor 1
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
NKAIN1 Na+/K+ transporting ATPase interacting 1
NME3 NME/NM23 nucleoside diphosphate kinase 3
NUBPL nucleotide binding protein-like
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
ONECUT2 one cut homeobox 2
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PARP16 poly (ADP-ribose) polymerase family, member 16
PCDHB8 protocadherin beta 8
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PLA2G10 phospholipase A2, group X
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
POR P450 (cytochrome) oxidoreductase
PRSS53 protease, serine, 53
PVRL3 poliovirus receptor-related 3
PYCRL pyrroline-5-carboxylate reductase-like
RAB3A RAB3A, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RNF208 ring finger protein 208
RPIA ribose 5-phosphate isomerase A
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SIX1 SIX homeobox 1
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC44A1 solute carrier family 44 (choline transporter), member 1
STRN striatin, calmodulin binding protein
TEP1 telomerase-associated protein 1
TGFBI transforming growth factor, beta-induced, 68kDa
TMEM180 transmembrane protein 180
TMEM38B transmembrane protein 38B
TMEM45A transmembrane protein 45A
TOM1 target of myb1 (chicken)
TPK1 thiamin pyrophosphokinase 1
TRPV6 transient receptor potential cation channel, subfamily V, member 6
UBXN8 UBX domain protein 8
WDR33 WD repeat domain 33
XYLT2 xylosyltransferase II
ZBED1 zinc finger, BED-type containing 1
ZC3H3 zinc finger CCCH-type containing 3
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF137P zinc finger protein 137, pseudogene
ZNF428 zinc finger protein 428
ZNF571 zinc finger protein 571
ZNF813 zinc finger protein 813