| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the ethotoin-4366 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAP1 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 |
| ADCK4 | aarF domain containing kinase 4 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ARSA | arylsulfatase A |
| B9D1 | B9 protein domain 1 |
| BST2 | bone marrow stromal cell antigen 2 |
| BTN3A1 | butyrophilin, subfamily 3, member A1 |
| C19ORF66 | chromosome 19 open reading frame 66 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CCKAR | cholecystokinin A receptor |
| CD58 | CD58 molecule |
| CEP41 | centrosomal protein 41kDa |
| CLEC4M | C-type lectin domain family 4, member M |
| CLTA | clathrin, light chain A |
| COL4A1 | collagen, type IV, alpha 1 |
| CPB1 | carboxypeptidase B1 (tissue) |
| CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant |
| CYB5A | cytochrome b5 type A (microsomal) |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DRD2 | dopamine receptor D2 |
| EGFR | epidermal growth factor receptor |
| ETNPPL | ethanolamine-phosphate phospho-lyase |
| FAM182B | family with sequence similarity 182, member B |
| FBXL18 | F-box and leucine-rich repeat protein 18 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| GFAP | glial fibrillary acidic protein |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| HFE | hemochromatosis |
| HIST1H1D | histone cluster 1, H1d |
| HNF1B | HNF1 homeobox B |
| HOXB3 | homeobox B3 |
| HRH3 | histamine receptor H3 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| IGLJ3 | immunoglobulin lambda joining 3 |
| IVL | involucrin |
| KCNC1 | potassium channel, voltage gated Shaw related subfamily C, member 1 |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KIAA0754 | KIAA0754 |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KLK13 | kallikrein-related peptidase 13 |
| LINC00574 | long intergenic non-protein coding RNA 574 |
| LMNB1 | lamin B1 |
| LSP1 | lymphocyte-specific protein 1 |
| MLXIP | MLX interacting protein |
| MMP25 | matrix metallopeptidase 25 |
| MORN1 | MORN repeat containing 1 |
| MTSS1 | metastasis suppressor 1 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| PAX8 | paired box 8 |
| PDE10A | phosphodiesterase 10A |
| PDX1 | pancreatic and duodenal homeobox 1 |
| PHLPP2 | PH domain and leucine rich repeat protein phosphatase 2 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLXNC1 | plexin C1 |
| POPDC3 | popeye domain containing 3 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRKCI | protein kinase C, iota |
| PRLH | prolactin releasing hormone |
| PTAFR | platelet-activating factor receptor |
| PTCRA | pre T-cell antigen receptor alpha |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RDH16 | retinol dehydrogenase 16 (all-trans) |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) |
| RHAG | Rh-associated glycoprotein |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| SAMD4A | sterile alpha motif domain containing 4A |
| SCG2 | secretogranin II |
| SFRP4 | secreted frizzled-related protein 4 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC34A1 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 |
| SLC6A13 | solute carrier family 6 (neurotransmitter transporter), member 13 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| STATH | statherin |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| SYP | synaptophysin |
| SYT11 | synaptotagmin XI |
| TCF4 | transcription factor 4 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TPP1 | tripeptidyl peptidase I |
| TRAF1 | TNF receptor-associated factor 1 |
| TRO | trophinin |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| ZFP64 | ZFP64 zinc finger protein |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADM | adrenomedullin |
| ALPK1 | alpha-kinase 1 |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| C1ORF21 | chromosome 1 open reading frame 21 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CEL | carboxyl ester lipase |
| CFHR4 | complement factor H-related 4 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHKB | choline kinase beta |
| CNTFR | ciliary neurotrophic factor receptor |
| CUEDC1 | CUE domain containing 1 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DAGLA | diacylglycerol lipase, alpha |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DNASE1L2 | deoxyribonuclease I-like 2 |
| EFNA3 | ephrin-A3 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| FGF13 | fibroblast growth factor 13 |
| FSHB | follicle stimulating hormone, beta polypeptide |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GPR1 | G protein-coupled receptor 1 |
| GSTP1 | glutathione S-transferase pi 1 |
| HCN4 | hyperpolarization activated cyclic nucleotide gated potassium channel 4 |
| HDAC5 | histone deacetylase 5 |
| HIST1H2AK | histone cluster 1, H2ak |
| HIST1H2BM | histone cluster 1, H2bm |
| HIST1H2BO | histone cluster 1, H2bo |
| HOXC8 | homeobox C8 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| ITM2C | integral membrane protein 2C |
| KIAA0319L | KIAA0319-like |
| KIAA1107 | KIAA1107 |
| KIF13B | kinesin family member 13B |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| LGALS9 | lectin, galactoside-binding, soluble, 9 |
| LHX1 | LIM homeobox 1 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LOC157562 | uncharacterized LOC157562 |
| LRRTM2 | leucine rich repeat transmembrane neuronal 2 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PGBD5 | piggyBac transposable element derived 5 |
| PICK1 | protein interacting with PRKCA 1 |
| PLA2G15 | phospholipase A2, group XV |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| RAB30 | RAB30, member RAS oncogene family |
| RECQL4 | RecQ protein-like 4 |
| RLN1 | relaxin 1 |
| RND1 | Rho family GTPase 1 |
| RNF122 | ring finger protein 122 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPL10L | ribosomal protein L10-like |
| SCARA3 | scavenger receptor class A, member 3 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STEAP4 | STEAP family member 4 |
| STIM1 | stromal interaction molecule 1 |
| TBC1D2 | TBC1 domain family, member 2 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 |
| TPSG1 | tryptase gamma 1 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TRIM68 | tripartite motif containing 68 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| UPK2 | uroplakin 2 |
| USP19 | ubiquitin specific peptidase 19 |
| VIM | vimentin |
| XAB2 | XPA binding protein 2 |
| XYLT2 | xylosyltransferase II |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZNF286A | zinc finger protein 286A |
| ZNF41 | zinc finger protein 41 |
| ZNF747 | zinc finger protein 747 |