| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the ethotoin-6052 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM5 | ADAM metallopeptidase domain 5 (pseudogene) |
| ADGRA2 | adhesion G protein-coupled receptor A2 |
| AIM2 | absent in melanoma 2 |
| AKAP6 | A kinase (PRKA) anchor protein 6 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| APOBEC1 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 |
| ARHGAP1 | Rho GTPase activating protein 1 |
| C14ORF105 | chromosome 14 open reading frame 105 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CCZ1 | CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) |
| CD6 | CD6 molecule |
| CDHR2 | cadherin-related family member 2 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CHN2 | chimerin 2 |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CYP4F2 | cytochrome P450, family 4, subfamily F, polypeptide 2 |
| DKFZP434L187 | uncharacterized LOC26082 |
| DOK4 | docking protein 4 |
| DRD1 | dopamine receptor D1 |
| DUSP13 | dual specificity phosphatase 13 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A |
| DYRK1B | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B |
| EPS15L1 | epidermal growth factor receptor pathway substrate 15-like 1 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FBXO40 | F-box protein 40 |
| FOXH1 | forkhead box H1 |
| FRMD4B | FERM domain containing 4B |
| FYB | FYN binding protein |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GNAS | GNAS complex locus |
| GPM6B | glycoprotein M6B |
| GRM8 | glutamate receptor, metabotropic 8 |
| GSTA3 | glutathione S-transferase alpha 3 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HOXB3 | homeobox B3 |
| HR | hair growth associated |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| IGFALS | insulin-like growth factor binding protein, acid labile subunit |
| IL5RA | interleukin 5 receptor, alpha |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| JPH3 | junctophilin 3 |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KIAA0195 | KIAA0195 |
| KIF21B | kinesin family member 21B |
| KIF25-AS1 | KIF25 antisense RNA 1 |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 |
| LOC100131532 | uncharacterized LOC100131532 |
| LRRN3 | leucine rich repeat neuronal 3 |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MATN1 | matrilin 1, cartilage matrix protein |
| MED25 | mediator complex subunit 25 |
| MFAP5 | microfibrillar associated protein 5 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| NAG18 | NAG18 mRNA |
| OR52A1 | olfactory receptor, family 52, subfamily A, member 1 |
| PAX5 | paired box 5 |
| PCM1 | pericentriolar material 1 |
| PDE10A | phosphodiesterase 10A |
| PDE11A | phosphodiesterase 11A |
| PDE12 | phosphodiesterase 12 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PRUNE2 | prune homolog 2 (Drosophila) |
| PRX | periaxin |
| RAP1GAP | RAP1 GTPase activating protein |
| RGS14 | regulator of G-protein signaling 14 |
| RHO | rhodopsin |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RORA | RAR-related orphan receptor A |
| RUNX1 | runt-related transcription factor 1 |
| RUNX2 | runt-related transcription factor 2 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCG2 | secretogranin II |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SIRPA | signal-regulatory protein alpha |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| STXBP5L | syntaxin binding protein 5-like |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TAS2R10 | taste receptor, type 2, member 10 |
| TCF3 | transcription factor 3 |
| TIMM8A | translocase of inner mitochondrial membrane 8 homolog A (yeast) |
| TMPRSS15 | transmembrane protease, serine 15 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| ZNF440 | zinc finger protein 440 |
| ZNF711 | zinc finger protein 711 |
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| ADM | adrenomedullin |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| AKTIP | AKT interacting protein |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARMC4 | armadillo repeat containing 4 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase |
| BAG4 | BCL2-associated athanogene 4 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| CAPG | capping protein (actin filament), gelsolin-like |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCDC186 | coiled-coil domain containing 186 |
| CCNO | cyclin O |
| CDC73 | cell division cycle 73 |
| CHIC2 | cysteine-rich hydrophobic domain 2 |
| CHML | choroideremia-like (Rab escort protein 2) |
| CISH | cytokine inducible SH2-containing protein |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CTSF | cathepsin F |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| EVA1B | eva-1 homolog B (C. elegans) |
| FAM172A | family with sequence similarity 172, member A |
| FAM204A | family with sequence similarity 204, member A |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GLI3 | GLI family zinc finger 3 |
| GPATCH2L | G patch domain containing 2-like |
| GPR21 | G protein-coupled receptor 21 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HOXA4 | homeobox A4 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFT22 | intraflagellar transport 22 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIFC1 | kinesin family member C1 |
| KLHL28 | kelch-like family member 28 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LINS | lines homolog (Drosophila) |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LRRC42 | leucine rich repeat containing 42 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 |
| PCDHA9 | protocadherin alpha 9 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PLEK2 | pleckstrin 2 |
| PMP22 | peripheral myelin protein 22 |
| PODXL2 | podocalyxin-like 2 |
| PRKX | protein kinase, X-linked |
| PROS1 | protein S (alpha) |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIN2 | Ras and Rab interactor 2 |
| SALL2 | spalt-like transcription factor 2 |
| SH2B3 | SH2B adaptor protein 3 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SLC9A6 | solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SYNGR3 | synaptogyrin 3 |
| TMC7 | transmembrane channel-like 7 |
| TMEM2 | transmembrane protein 2 |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| ULBP2 | UL16 binding protein 2 |
| USB1 | U6 snRNA biogenesis 1 |
| VASH2 | vasohibin 2 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) |
| YY2 | YY2 transcription factor |
| ZFP69B | ZFP69 zinc finger protein B |
| ZNF165 | zinc finger protein 165 |
| ZNF232 | zinc finger protein 232 |
| ZNF250 | zinc finger protein 250 |
| ZNF286A | zinc finger protein 286A |
| ZNF34 | zinc finger protein 34 |
| ZNF41 | zinc finger protein 41 |
| ZNF675 | zinc finger protein 675 |