ethotoin-6052 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the ethotoin-6052 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ADGRA2 adhesion G protein-coupled receptor A2
AIM2 absent in melanoma 2
AKAP6 A kinase (PRKA) anchor protein 6
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
ARHGAP1 Rho GTPase activating protein 1
C14ORF105 chromosome 14 open reading frame 105
C1QTNF1 C1q and tumor necrosis factor related protein 1
CCRL2 chemokine (C-C motif) receptor-like 2
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CD6 CD6 molecule
CDHR2 cadherin-related family member 2
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHN2 chimerin 2
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DKFZP434L187 uncharacterized LOC26082
DOK4 docking protein 4
DRD1 dopamine receptor D1
DUSP13 dual specificity phosphatase 13
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
EYA3 EYA transcriptional coactivator and phosphatase 3
FBXO40 F-box protein 40
FOXH1 forkhead box H1
FRMD4B FERM domain containing 4B
FYB FYN binding protein
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNAS GNAS complex locus
GPM6B glycoprotein M6B
GRM8 glutamate receptor, metabotropic 8
GSTA3 glutathione S-transferase alpha 3
GULP1 GULP, engulfment adaptor PTB domain containing 1
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HOXB3 homeobox B3
HR hair growth associated
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFALS insulin-like growth factor binding protein, acid labile subunit
IL5RA interleukin 5 receptor, alpha
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JPH3 junctophilin 3
KANSL3 KAT8 regulatory NSL complex subunit 3
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KIAA0195 KIAA0195
KIF21B kinesin family member 21B
KIF25-AS1 KIF25 antisense RNA 1
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LOC100131532 uncharacterized LOC100131532
LRRN3 leucine rich repeat neuronal 3
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MATN1 matrilin 1, cartilage matrix protein
MED25 mediator complex subunit 25
MFAP5 microfibrillar associated protein 5
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NAG18 NAG18 mRNA
OR52A1 olfactory receptor, family 52, subfamily A, member 1
PAX5 paired box 5
PCM1 pericentriolar material 1
PDE10A phosphodiesterase 10A
PDE11A phosphodiesterase 11A
PDE12 phosphodiesterase 12
PHLDB1 pleckstrin homology-like domain, family B, member 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PRUNE2 prune homolog 2 (Drosophila)
PRX periaxin
RAP1GAP RAP1 GTPase activating protein
RGS14 regulator of G-protein signaling 14
RHO rhodopsin
RNF126P1 ring finger protein 126 pseudogene 1
RORA RAR-related orphan receptor A
RUNX1 runt-related transcription factor 1
RUNX2 runt-related transcription factor 2
SAMD9 sterile alpha motif domain containing 9
SCG2 secretogranin II
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SIRPA signal-regulatory protein alpha
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STXBP5L syntaxin binding protein 5-like
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TAS2R10 taste receptor, type 2, member 10
TCF3 transcription factor 3
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TMPRSS15 transmembrane protease, serine 15
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
ZNF440 zinc finger protein 440
ZNF711 zinc finger protein 711

decreased expression

Symbol Name
ACTL8 actin-like 8
ADM adrenomedullin
AKAP12 A kinase (PRKA) anchor protein 12
AKTIP AKT interacting protein
ANP32A-IT1 ANP32A intronic transcript 1
APOLD1 apolipoprotein L domain containing 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARMC4 armadillo repeat containing 4
ASPHD1 aspartate beta-hydroxylase domain containing 1
AUH AU RNA binding protein/enoyl-CoA hydratase
BAG4 BCL2-associated athanogene 4
BAHCC1 BAH domain and coiled-coil containing 1
C1QTNF3 C1q and tumor necrosis factor related protein 3
CAPG capping protein (actin filament), gelsolin-like
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC186 coiled-coil domain containing 186
CCNO cyclin O
CDC73 cell division cycle 73
CHIC2 cysteine-rich hydrophobic domain 2
CHML choroideremia-like (Rab escort protein 2)
CISH cytokine inducible SH2-containing protein
CRABP1 cellular retinoic acid binding protein 1
CTSF cathepsin F
CUZD1 CUB and zona pellucida-like domains 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DGAT1 diacylglycerol O-acyltransferase 1
ELOVL4 ELOVL fatty acid elongase 4
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ETAA1 Ewing tumor-associated antigen 1
EVA1B eva-1 homolog B (C. elegans)
FAM172A family with sequence similarity 172, member A
FAM204A family with sequence similarity 204, member A
FBXL6 F-box and leucine-rich repeat protein 6
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
GBP2 guanylate binding protein 2, interferon-inducible
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GLI3 GLI family zinc finger 3
GPATCH2L G patch domain containing 2-like
GPR21 G protein-coupled receptor 21
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HAUS6 HAUS augmin-like complex, subunit 6
HOXA4 homeobox A4
IDI2-AS1 IDI2 antisense RNA 1
IFT22 intraflagellar transport 22
KDM8 lysine (K)-specific demethylase 8
KIFC1 kinesin family member C1
KLHL28 kelch-like family member 28
KREMEN2 kringle containing transmembrane protein 2
LINS lines homolog (Drosophila)
LMO2 LIM domain only 2 (rhombotin-like 1)
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRRC42 leucine rich repeat containing 42
LZTR1 leucine-zipper-like transcription regulator 1
MAST3 microtubule associated serine/threonine kinase 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MKNK2 MAP kinase interacting serine/threonine kinase 2
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PCDHA9 protocadherin alpha 9
PCSK7 proprotein convertase subtilisin/kexin type 7
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PLEK2 pleckstrin 2
PMP22 peripheral myelin protein 22
PODXL2 podocalyxin-like 2
PRKX protein kinase, X-linked
PROS1 protein S (alpha)
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
RAP1GAP2 RAP1 GTPase activating protein 2
RASAL1 RAS protein activator like 1 (GAP1 like)
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIN2 Ras and Rab interactor 2
SALL2 spalt-like transcription factor 2
SH2B3 SH2B adaptor protein 3
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SYNGR3 synaptogyrin 3
TMC7 transmembrane channel-like 7
TMEM2 transmembrane protein 2
TOE1 target of EGR1, member 1 (nuclear)
TPST2 tyrosylprotein sulfotransferase 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
ULBP2 UL16 binding protein 2
USB1 U6 snRNA biogenesis 1
VASH2 vasohibin 2
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
YY2 YY2 transcription factor
ZFP69B ZFP69 zinc finger protein B
ZNF165 zinc finger protein 165
ZNF232 zinc finger protein 232
ZNF250 zinc finger protein 250
ZNF286A zinc finger protein 286A
ZNF34 zinc finger protein 34
ZNF41 zinc finger protein 41
ZNF675 zinc finger protein 675