ethoxyquin-3421 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the ethoxyquin-3421 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ACTN2 actinin, alpha 2
ADAM12 ADAM metallopeptidase domain 12
AKAP8L A kinase (PRKA) anchor protein 8-like
AKR1C1 aldo-keto reductase family 1, member C1
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALPPL2 alkaline phosphatase, placental-like 2
APOM apolipoprotein M
ARHGAP35 Rho GTPase activating protein 35
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ASPH aspartate beta-hydroxylase
ATF3 activating transcription factor 3
BBS9 Bardet-Biedl syndrome 9
C11ORF63 chromosome 11 open reading frame 63
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAPN9 calpain 9
CBX4 chromobox homolog 4
CCPG1 cell cycle progression 1
CD1E CD1e molecule
CD8A CD8a molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
COL8A2 collagen, type VIII, alpha 2
CYLD cylindromatosis (turban tumor syndrome)
DOC2A double C2-like domains, alpha
EDNRA endothelin receptor type A
ERN2 endoplasmic reticulum to nucleus signaling 2
ESR2 estrogen receptor 2 (ER beta)
FGF4 fibroblast growth factor 4
FGFR1 fibroblast growth factor receptor 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GAL3ST4 galactose-3-O-sulfotransferase 4
GAMT guanidinoacetate N-methyltransferase
GLRA1 glycine receptor, alpha 1
HLA-C major histocompatibility complex, class I, C
HMOX1 heme oxygenase 1
HOMER3 homer scaffolding protein 3
HP haptoglobin
HR hair growth associated
IFT38 intraflagellar transport 38
INHBE inhibin, beta E
ITGB4 integrin, beta 4
KATNB1 katanin p80 (WD repeat containing) subunit B 1
LBP lipopolysaccharide binding protein
LEPR leptin receptor
LHX2 LIM homeobox 2
LMO4 LIM domain only 4
LOC100286895 cell division cycle 27 homolog pseudogene
LOC647070 uncharacterized LOC647070
LPCAT4 lysophosphatidylcholine acyltransferase 4
MAPK14 mitogen-activated protein kinase 14
MID1 midline 1
MTAP methylthioadenosine phosphorylase
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NME5 NME/NM23 family member 5
NMT2 N-myristoyltransferase 2
NR2F1 nuclear receptor subfamily 2, group F, member 1
OVGP1 oviductal glycoprotein 1, 120kDa
PACS1 phosphofurin acidic cluster sorting protein 1
PAPOLA poly(A) polymerase alpha
PDGFB platelet-derived growth factor beta polypeptide
PIAS4 protein inhibitor of activated STAT, 4
PITX1 paired-like homeodomain 1
PITX2 paired-like homeodomain 2
PTGDR2 prostaglandin D2 receptor 2
RABGAP1 RAB GTPase activating protein 1
RBM12B RNA binding motif protein 12B
RECQL5 RecQ protein-like 5
RGS10 regulator of G-protein signaling 10
RGS3 regulator of G-protein signaling 3
RNASEH2B ribonuclease H2, subunit B
RPLP2 ribosomal protein, large, P2
RRAGD Ras-related GTP binding D
RREB1 ras responsive element binding protein 1
RUSC2 RUN and SH3 domain containing 2
S100A13 S100 calcium binding protein A13
SCAI suppressor of cancer cell invasion
SCN10A sodium channel, voltage gated, type X alpha subunit
SETD1B SET domain containing 1B
SIN3B SIN3 transcription regulator family member B
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SOS2 son of sevenless homolog 2 (Drosophila)
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TAOK1 TAO kinase 1
THRA thyroid hormone receptor, alpha
TLR2 toll-like receptor 2
TM4SF1 transmembrane 4 L six family member 1
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TOP3B topoisomerase (DNA) III beta
TPP1 tripeptidyl peptidase I
TRD T cell receptor delta locus
TUBGCP2 tubulin, gamma complex associated protein 2
UBQLN4 ubiquilin 4
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
WDR62 WD repeat domain 62
WDTC1 WD and tetratricopeptide repeats 1
WFDC2 WAP four-disulfide core domain 2
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF444 zinc finger protein 444

decreased expression

Symbol Name
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADCY6 adenylate cyclase 6
ADGRE5 adhesion G protein-coupled receptor E5
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ARL15 ADP-ribosylation factor-like 15
ATAD5 ATPase family, AAA domain containing 5
AZI2 5-azacytidine induced 2
BCL9 B-cell CLL/lymphoma 9
BMP4 bone morphogenetic protein 4
C14ORF93 chromosome 14 open reading frame 93
C17ORF80 chromosome 17 open reading frame 80
C2ORF44 chromosome 2 open reading frame 44
C7ORF43 chromosome 7 open reading frame 43
CALCOCO1 calcium binding and coiled-coil domain 1
CASZ1 castor zinc finger 1
CCDC109B coiled-coil domain containing 109B
CCDC88C coiled-coil domain containing 88C
CCDC9 coiled-coil domain containing 9
CCNE1 cyclin E1
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CFAP44 cilia and flagella associated protein 44
CGREF1 cell growth regulator with EF-hand domain 1
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHRM3 cholinergic receptor, muscarinic 3
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLDN9 claudin 9
CLSPN claspin
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRLF1 cytokine receptor-like factor 1
CTDNEP1 CTD nuclear envelope phosphatase 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
ELMO3 engulfment and cell motility 3
F3 coagulation factor III (thromboplastin, tissue factor)
FANCC Fanconi anemia, complementation group C
FEM1C fem-1 homolog c (C. elegans)
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
FZD4 frizzled class receptor 4
GLB1L2 galactosidase, beta 1-like 2
GLI3 GLI family zinc finger 3
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPRC5C G protein-coupled receptor, class C, group 5, member C
HAUS6 HAUS augmin-like complex, subunit 6
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
HIRA histone cell cycle regulator
IL4R interleukin 4 receptor
INPPL1 inositol polyphosphate phosphatase-like 1
JMJD4 jumonji domain containing 4
KCTD20 potassium channel tetramerization domain containing 20
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
METRN meteorin, glial cell differentiation regulator
MRPL52 mitochondrial ribosomal protein L52
MTG1 mitochondrial ribosome-associated GTPase 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NFE2L3 nuclear factor, erythroid 2-like 3
NME6 NME/NM23 nucleoside diphosphate kinase 6
NT5DC3 5'-nucleotidase domain containing 3
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PIBF1 progesterone immunomodulatory binding factor 1
PLA2G3 phospholipase A2, group III
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
S100A4 S100 calcium binding protein A4
SH2B3 SH2B adaptor protein 3
SIRT6 sirtuin 6
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
THAP4 THAP domain containing 4
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TMEM127 transmembrane protein 127
TMEM180 transmembrane protein 180
TMEM184B transmembrane protein 184B
TMEM62 transmembrane protein 62
TRABD TraB domain containing
UBA3 ubiquitin-like modifier activating enzyme 3
WDR76 WD repeat domain 76
YBX2 Y box binding protein 2
ZBED1 zinc finger, BED-type containing 1
ZNF141 zinc finger protein 141
ZNF250 zinc finger protein 250
ZNF324 zinc finger protein 324
ZNF480 zinc finger protein 480
ZNF7 zinc finger protein 7
ZNF83 zinc finger protein 83
ZNRD1-AS1 ZNRD1 antisense RNA 1