| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the ethoxyquin-3764 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOXL | acyl-CoA oxidase-like |
| ALPK1 | alpha-kinase 1 |
| ARSA | arylsulfatase A |
| ASTN1 | astrotactin 1 |
| ATN1 | atrophin 1 |
| ATP10B | ATPase, class V, type 10B |
| ATP2B3 | ATPase, Ca++ transporting, plasma membrane 3 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BEGAIN | brain-enriched guanylate kinase-associated |
| BMP5 | bone morphogenetic protein 5 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C2ORF72 | chromosome 2 open reading frame 72 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CD7 | CD7 molecule |
| CHRNA4 | cholinergic receptor, nicotinic, alpha 4 (neuronal) |
| CLEC10A | C-type lectin domain family 10, member A |
| CNTFR | ciliary neurotrophic factor receptor |
| COL10A1 | collagen, type X, alpha 1 |
| COL17A1 | collagen, type XVII, alpha 1 |
| CRHR1 | corticotropin releasing hormone receptor 1 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| DTNA | dystrobrevin, alpha |
| EGFL7 | EGF-like-domain, multiple 7 |
| EHD2 | EH-domain containing 2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ESR1 | estrogen receptor 1 |
| EXOSC2 | exosome component 2 |
| FGF18 | fibroblast growth factor 18 |
| FHIT | fragile histidine triad |
| FOSL2 | FOS-like antigen 2 |
| GARNL3 | GTPase activating Rap/RanGAP domain-like 3 |
| GFI1 | growth factor independent 1 transcription repressor |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| HEYL | hes-related family bHLH transcription factor with YRPW motif-like |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H2BN | histone cluster 1, H2bn |
| HNF4A | hepatocyte nuclear factor 4, alpha |
| ICAM2 | intercellular adhesion molecule 2 |
| IDS | iduronate 2-sulfatase |
| IGF1R | insulin-like growth factor 1 receptor |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| KIAA1549L | KIAA1549-like |
| KIR2DL1 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 |
| KLF13 | Kruppel-like factor 13 |
| KLHL22 | kelch-like family member 22 |
| KLK12 | kallikrein-related peptidase 12 |
| KRT32 | keratin 32, type I |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAP1B | microtubule-associated protein 1B |
| MPPE1 | metallophosphoesterase 1 |
| MS4A2 | membrane-spanning 4-domains, subfamily A, member 2 |
| NCALD | neurocalcin delta |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OLFML2B | olfactomedin-like 2B |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 |
| PAPPA2 | pappalysin 2 |
| PCDH11Y | protocadherin 11 Y-linked |
| PHF3 | PHD finger protein 3 |
| PLIN2 | perilipin 2 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| POU1F1 | POU class 1 homeobox 1 |
| PRY | PTPN13-like, Y-linked |
| RGS12 | regulator of G-protein signaling 12 |
| RNF208 | ring finger protein 208 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
| SFTPB | surfactant protein B |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLC5A4 | solute carrier family 5 (glucose activated ion channel), member 4 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| SOX21 | SRY (sex determining region Y)-box 21 |
| SP1 | Sp1 transcription factor |
| SPAG8 | sperm associated antigen 8 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| SYMPK | symplekin |
| TBC1D1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 |
| TBCD | tubulin folding cofactor D |
| TEF | thyrotrophic embryonic factor |
| TFR2 | transferrin receptor 2 |
| TLK1 | tousled-like kinase 1 |
| TMEM144 | transmembrane protein 144 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TP53TG5 | TP53 target 5 |
| USP29 | ubiquitin specific peptidase 29 |
| VHL | von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase |
| WDR62 | WD repeat domain 62 |
| ZNF223 | zinc finger protein 223 |
| ZNF280A | zinc finger protein 280A |
| ZNF516 | zinc finger protein 516 |
| ZNF646 | zinc finger protein 646 |
| Symbol | Name |
|---|---|
| ACBD4 | acyl-CoA binding domain containing 4 |
| ADAM23 | ADAM metallopeptidase domain 23 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARHGAP22 | Rho GTPase activating protein 22 |
| BAX | BCL2-associated X protein |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C5ORF42 | chromosome 5 open reading frame 42 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCDC106 | coiled-coil domain containing 106 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CD34 | CD34 molecule |
| CHMP6 | charged multivesicular body protein 6 |
| CINP | cyclin-dependent kinase 2 interacting protein |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CPNE7 | copine VII |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CYBRD1 | cytochrome b reductase 1 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| FAM204A | family with sequence similarity 204, member A |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLCN | folliculin |
| FMOD | fibromodulin |
| GALT | galactose-1-phosphate uridylyltransferase |
| GAS2 | growth arrest-specific 2 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GPR19 | G protein-coupled receptor 19 |
| HIST1H2AB | histone cluster 1, H2ab |
| HIST1H2BM | histone cluster 1, H2bm |
| HOXC11 | homeobox C11 |
| IFNA17 | interferon, alpha 17 |
| IL22 | interleukin 22 |
| INO80D | INO80 complex subunit D |
| IPO8 | importin 8 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KIAA1107 | KIAA1107 |
| KIAA1462 | KIAA1462 |
| LIMD2 | LIM domain containing 2 |
| LRRC15 | leucine rich repeat containing 15 |
| LY86 | lymphocyte antigen 86 |
| MAP3K7CL | MAP3K7 C-terminal like |
| MN1 | meningioma (disrupted in balanced translocation) 1 |
| NADSYN1 | NAD synthetase 1 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NELL2 | NEL-like 2 (chicken) |
| NGF | nerve growth factor (beta polypeptide) |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| OLFML2A | olfactomedin-like 2A |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| OVOL1 | ovo-like zinc finger 1 |
| PDE12 | phosphodiesterase 12 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLXNA3 | plexin A3 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PQLC2 | PQ loop repeat containing 2 |
| PRSS53 | protease, serine, 53 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
| RFPL3 | ret finger protein-like 3 |
| RNF122 | ring finger protein 122 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RNF43 | ring finger protein 43 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| S100A3 | S100 calcium binding protein A3 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCN8A | sodium channel, voltage gated, type VIII alpha subunit |
| SCNN1B | sodium channel, non voltage gated 1 beta subunit |
| SEC14L5 | SEC14-like 5 (S. cerevisiae) |
| SETD1A | SET domain containing 1A |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SPATA2L | spermatogenesis associated 2-like |
| STK16 | serine/threonine kinase 16 |
| STXBP5L | syntaxin binding protein 5-like |
| SYTL2 | synaptotagmin-like 2 |
| TRIM9 | tripartite motif containing 9 |
| TSPAN2 | tetraspanin 2 |
| VLDLR | very low density lipoprotein receptor |
| WDR25 | WD repeat domain 25 |
| WFDC2 | WAP four-disulfide core domain 2 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF573 | zinc finger protein 573 |
| ZNF671 | zinc finger protein 671 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZNF768 | zinc finger protein 768 |
| ZNF816 | zinc finger protein 816 |