ethoxyquin-3846 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the ethoxyquin-3846 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADD2 adducin 2 (beta)
ADGRG1 adhesion G protein-coupled receptor G1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
APOC1 apolipoprotein C-I
APOL3 apolipoprotein L, 3
ATF3 activating transcription factor 3
ATP11A ATPase, class VI, type 11A
BTG2 BTG family, member 2
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CASP1 caspase 1, apoptosis-related cysteine peptidase
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLGN calmegin
COL1A1 collagen, type I, alpha 1
COPA coatomer protein complex, subunit alpha
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DAPK3 death-associated protein kinase 3
DIAPH2-AS1 DIAPH2 antisense RNA 1
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
DSC2 desmocollin 2
DST dystonin
ECEL1 endothelin converting enzyme-like 1
FADS2 fatty acid desaturase 2
FCMR Fc fragment of IgM receptor
FGF6 fibroblast growth factor 6
FHL1 four and a half LIM domains 1
FOSL2 FOS-like antigen 2
FRAS1 Fraser extracellular matrix complex subunit 1
GNRHR gonadotropin-releasing hormone receptor
GPR137 G protein-coupled receptor 137
HFE hemochromatosis
HMOX1 heme oxygenase 1
HNRNPM heterogeneous nuclear ribonucleoprotein M
HOXA7 homeobox A7
ICOSLG inducible T-cell co-stimulator ligand
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL6ST interleukin 6 signal transducer
INHBE inhibin, beta E
KLHL22 kelch-like family member 22
LAMP1 lysosomal-associated membrane protein 1
LHX2 LIM homeobox 2
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAPK10 mitogen-activated protein kinase 10
MAPK14 mitogen-activated protein kinase 14
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MCAM melanoma cell adhesion molecule
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MTL5 metallothionein-like 5, testis-specific (tesmin)
NDOR1 NADPH dependent diflavin oxidoreductase 1
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NTN3 netrin 3
OASL 2'-5'-oligoadenylate synthetase-like
OXCT2 3-oxoacid CoA transferase 2
PAIP2B poly(A) binding protein interacting protein 2B
PKNOX1 PBX/knotted 1 homeobox 1
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLK3 polo-like kinase 3
PLXNB3 plexin B3
PQLC3 PQ loop repeat containing 3
PRM1 protamine 1
PTCRA pre T-cell antigen receptor alpha
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAB40A RAB40A, member RAS oncogene family
RB1 retinoblastoma 1
RCAN3 RCAN family member 3
RPL23AP53 ribosomal protein L23a pseudogene 53
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
RUNX1 runt-related transcription factor 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SERHL2 serine hydrolase-like 2
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX4 SRY (sex determining region Y)-box 4
SP1 Sp1 transcription factor
SPEG SPEG complex locus
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
ST7L suppression of tumorigenicity 7 like
TAPBP TAP binding protein (tapasin)
TBC1D22B TBC1 domain family, member 22B
TBL2 transducin (beta)-like 2
THTPA thiamine triphosphatase
TM2D1 TM2 domain containing 1
TMOD2 tropomodulin 2 (neuronal)
TMPRSS2 transmembrane protease, serine 2
TMX4 thioredoxin-related transmembrane protein 4
TNPO2 transportin 2
TPMT thiopurine S-methyltransferase
TRIM15 tripartite motif containing 15
UBE3A ubiquitin protein ligase E3A
UTRN utrophin
VEGFA vascular endothelial growth factor A
VNN2 vanin 2
WDFY3 WD repeat and FYVE domain containing 3
ZNF507 zinc finger protein 507

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACTL8 actin-like 8
ADCY7 adenylate cyclase 7
ALOX15 arachidonate 15-lipoxygenase
ALPK1 alpha-kinase 1
ANKH ANKH inorganic pyrophosphate transport regulator
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BIRC7 baculoviral IAP repeat containing 7
C11ORF30 chromosome 11 open reading frame 30
C19ORF73 chromosome 19 open reading frame 73
C22ORF46 chromosome 22 open reading frame 46
C4BPA complement component 4 binding protein, alpha
C5 complement component 5
CBX8 chromobox homolog 8
CCDC9 coiled-coil domain containing 9
CCNO cyclin O
CNGB3 cyclic nucleotide gated channel beta 3
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCAF4 DDB1 and CUL4 associated factor 4
DCBLD2 discoidin, CUB and LCCL domain containing 2
DEPDC5 DEP domain containing 5
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DYM dymeclin
EGFL7 EGF-like-domain, multiple 7
EMID1 EMI domain containing 1
ENO3 enolase 3 (beta, muscle)
FAM160B2 family with sequence similarity 160, member B2
FFAR2 free fatty acid receptor 2
FXYD5 FXYD domain containing ion transport regulator 5
GEMIN8 gem (nuclear organelle) associated protein 8
GNL1 guanine nucleotide binding protein-like 1
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
HIST1H1B histone cluster 1, H1b
HIST1H2AI histone cluster 1, H2ai
HIST1H2AJ histone cluster 1, H2aj
HIST1H2AL histone cluster 1, H2al
HIST1H4C histone cluster 1, H4c
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFI6 interferon, alpha-inducible protein 6
IFNA14 interferon, alpha 14
IFT54 intraflagellar transport 54
IGFBP6 insulin-like growth factor binding protein 6
KIAA1107 KIAA1107
KRT15 keratin 15, type I
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LOC390998 ribosomal protein L10 pseudogene
MAP1S microtubule-associated protein 1S
MAST3 microtubule associated serine/threonine kinase 3
MMP3 matrix metallopeptidase 3
NXPH4 neurexophilin 4
PACS1 phosphofurin acidic cluster sorting protein 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLEKHS1 pleckstrin homology domain containing, family S member 1
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PRKCE protein kinase C, epsilon
PTPRS protein tyrosine phosphatase, receptor type, S
RAB36 RAB36, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SHARPIN SHANK-associated RH domain interactor
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLMO1 slowmo homolog 1 (Drosophila)
SLPI secretory leukocyte peptidase inhibitor
TAOK1 TAO kinase 1
TBL1Y transducin (beta)-like 1, Y-linked
TFF2 trefoil factor 2
TMEM120B transmembrane protein 120B
TOM1 target of myb1 (chicken)
TOR4A torsin family 4, member A
TRIM68 tripartite motif containing 68
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UPK3B uroplakin 3B
USP27X ubiquitin specific peptidase 27, X-linked
VASH1 vasohibin 1
VPS9D1 VPS9 domain containing 1
WFDC2 WAP four-disulfide core domain 2
YY2 YY2 transcription factor
ZBTB22 zinc finger and BTB domain containing 22
ZC3H3 zinc finger CCCH-type containing 3
ZDHHC14 zinc finger, DHHC-type containing 14
ZMAT4 zinc finger, matrin-type 4
ZNF212 zinc finger protein 212
ZNF286A zinc finger protein 286A
ZNF358 zinc finger protein 358
ZNF574 zinc finger protein 574
ZNF747 zinc finger protein 747
ZSCAN2 zinc finger and SCAN domain containing 2