ethoxyquin Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
Description A quinoline that is 1,2-dihydroquinoline bearing three methyl substituents at position 2, 2 and 4 as well as an ethoxy substituent at position 6. (Chemical Entities of Biological Interest Ontology, CHEBI_77323)
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Genes

9 genes differentially expressed following the ethoxyquin small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
TOMM34 translocase of outer mitochondrial membrane 34 3.54276
OSGIN2 oxidative stress induced growth inhibitor family member 2 3.06445
CALU calumenin 3.05005

decreased expression

Symbol Name Standardized Value
ZMYM2 zinc finger, MYM-type 2 -5.40369
IFNAR1 interferon (alpha, beta and omega) receptor 1 -3.67394
EPHB2 EPH receptor B2 -3.52821
SKP1 S-phase kinase-associated protein 1 -3.31031
EYA2 EYA transcriptional coactivator and phosphatase 2 -3.21887
USP6NL USP6 N-terminal like -3.14045