eticlopride-3393 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the eticlopride-3393 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ADAM22 ADAM metallopeptidase domain 22
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADGRA2 adhesion G protein-coupled receptor A2
AIM1L absent in melanoma 1-like
AKAP1 A kinase (PRKA) anchor protein 1
AKAP8L A kinase (PRKA) anchor protein 8-like
ALCAM activated leukocyte cell adhesion molecule
AMPD3 adenosine monophosphate deaminase 3
APOM apolipoprotein M
ARC activity-regulated cytoskeleton-associated protein
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ATN1 atrophin 1
BDKRB2 bradykinin receptor B2
BLNK B-cell linker
C1S complement component 1, s subcomponent
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CD1A CD1a molecule
CD47 CD47 molecule
CDON cell adhesion associated, oncogene regulated
CLEC2D C-type lectin domain family 2, member D
CNN1 calponin 1, basic, smooth muscle
COL6A1 collagen, type VI, alpha 1
CRHR2 corticotropin releasing hormone receptor 2
CRTC1 CREB regulated transcription coactivator 1
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DBP D site of albumin promoter (albumin D-box) binding protein
DGCR8 DGCR8 microprocessor complex subunit
DIO2 deiodinase, iodothyronine, type II
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
DOCK3 dedicator of cytokinesis 3
DTX3 deltex 3, E3 ubiquitin ligase
EFCAB2 EF-hand calcium binding domain 2
EHD2 EH-domain containing 2
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
ERCC2 excision repair cross-complementation group 2
ERP44 endoplasmic reticulum protein 44
ESM1 endothelial cell-specific molecule 1
FHL1 four and a half LIM domains 1
FYB FYN binding protein
GM2A GM2 ganglioside activator
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GOLGA8A golgin A8 family, member A
GP2 glycoprotein 2 (zymogen granule membrane)
HFE hemochromatosis
HOXA7 homeobox A7
HSF4 heat shock transcription factor 4
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFNA17 interferon, alpha 17
INHBE inhibin, beta E
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
KIAA1456 KIAA1456
KIDINS220 kinase D-interacting substrate, 220kDa
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KRT8 keratin 8, type II
LDLRAD4 low density lipoprotein receptor class A domain containing 4
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAN1C1 mannosidase, alpha, class 1C, member 1
MAP1A microtubule-associated protein 1A
MET MET proto-oncogene, receptor tyrosine kinase
MFAP5 microfibrillar associated protein 5
MIER2 mesoderm induction early response 1, family member 2
MLXIPL MLX interacting protein-like
MRPL41 mitochondrial ribosomal protein L41
MST1 macrophage stimulating 1
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MX1 MX dynamin-like GTPase 1
NRDE2 NRDE-2, necessary for RNA interference, domain containing
NRF1 nuclear respiratory factor 1
NRN1 neuritin 1
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
NUP50 nucleoporin 50kDa
OMD osteomodulin
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCNXL2 pecanex-like 2 (Drosophila)
PHTF2 putative homeodomain transcription factor 2
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLXNA2 plexin A2
PTAFR platelet-activating factor receptor
PVR poliovirus receptor
RAB6A RAB6A, member RAS oncogene family
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
SH2D3A SH2 domain containing 3A
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SNCAIP synuclein, alpha interacting protein
SOX2 SRY (sex determining region Y)-box 2
SRSF7 serine/arginine-rich splicing factor 7
TLR2 toll-like receptor 2
TMOD1 tropomodulin 1
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TPMT thiopurine S-methyltransferase
TRIM38 tripartite motif containing 38
UBTD1 ubiquitin domain containing 1
UHRF1BP1L UHRF1 binding protein 1-like
VAC14 Vac14 homolog (S. cerevisiae)
ZMAT4 zinc finger, matrin-type 4

decreased expression

Symbol Name
ADM adrenomedullin
ADTRP androgen-dependent TFPI-regulating protein
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARPIN actin-related protein 2/3 complex inhibitor
BMP15 bone morphogenetic protein 15
BTF3P12 basic transcription factor 3 pseudogene 12
C1ORF105 chromosome 1 open reading frame 105
CARD8 caspase recruitment domain family, member 8
CD3D CD3d molecule, delta (CD3-TCR complex)
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CORO7 coronin 7
CPA4 carboxypeptidase A4
CTRL chymotrypsin-like
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DLK2 delta-like 2 homolog (Drosophila)
DNAH17 dynein, axonemal, heavy chain 17
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DOK5 docking protein 5
EMID1 EMI domain containing 1
EPB41L5 erythrocyte membrane protein band 4.1 like 5
FAM46C family with sequence similarity 46, member C
FGF23 fibroblast growth factor 23
FSCN3 fascin actin-bundling protein 3, testicular
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GFI1 growth factor independent 1 transcription repressor
GJA9 gap junction protein, alpha 9, 59kDa
GLDC glycine dehydrogenase (decarboxylating)
GLRA1 glycine receptor, alpha 1
GPR1 G protein-coupled receptor 1
GPR143 G protein-coupled receptor 143
GPR21 G protein-coupled receptor 21
GPR27 G protein-coupled receptor 27
HIST1H2BC histone cluster 1, H2bc
HMOX1 heme oxygenase 1
IL4R interleukin 4 receptor
INO80D INO80 complex subunit D
KDM8 lysine (K)-specific demethylase 8
KIAA0319L KIAA0319-like
LIF leukemia inhibitory factor
LIME1 Lck interacting transmembrane adaptor 1
LRRC61 leucine rich repeat containing 61
MAGEA5 melanoma antigen family A5
MAL mal, T-cell differentiation protein
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MCOLN3 mucolipin 3
MEFV Mediterranean fever
MFGE8 milk fat globule-EGF factor 8 protein
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NRGN neurogranin (protein kinase C substrate, RC3)
NT5DC3 5'-nucleotidase domain containing 3
NYNRIN NYN domain and retroviral integrase containing
PDE8B phosphodiesterase 8B
PDIA3 protein disulfide isomerase family A, member 3
PHC1 polyhomeotic homolog 1 (Drosophila)
PHF14 PHD finger protein 14
PLEKHS1 pleckstrin homology domain containing, family S member 1
PODNL1 podocan-like 1
POM121L2 POM121 transmembrane nucleoporin-like 2
PRKCE protein kinase C, epsilon
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PRSS16 protease, serine, 16 (thymus)
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
QPCT glutaminyl-peptide cyclotransferase
RAB40AL RAB40A, member RAS oncogene family-like
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RHBG Rh family, B glycoprotein (gene/pseudogene)
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SAYSD1 SAYSVFN motif domain containing 1
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SERGEF secretion regulating guanine nucleotide exchange factor
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLIT2 slit homolog 2 (Drosophila)
SLMO1 slowmo homolog 1 (Drosophila)
SPEG SPEG complex locus
SPINK4 serine peptidase inhibitor, Kazal type 4
SPINK5 serine peptidase inhibitor, Kazal type 5
SSTR4 somatostatin receptor 4
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAS2R10 taste receptor, type 2, member 10
TBC1D2 TBC1 domain family, member 2
TDRD12 tudor domain containing 12
TGFBR3 transforming growth factor, beta receptor III
THNSL2 threonine synthase-like 2 (S. cerevisiae)
THRAP3 thyroid hormone receptor associated protein 3
TMEM8B transmembrane protein 8B
TNS2 tensin 2
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSC22D4 TSC22 domain family, member 4
UPK2 uroplakin 2
USB1 U6 snRNA biogenesis 1
VEZT vezatin, adherens junctions transmembrane protein
XYLT1 xylosyltransferase I
ZNF606 zinc finger protein 606
ZSWIM1 zinc finger, SWIM-type containing 1