eticlopride-4634 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the eticlopride-4634 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ADAM3A ADAM metallopeptidase domain 3A (pseudogene)
ADCY6 adenylate cyclase 6
ADPRH ADP-ribosylarginine hydrolase
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ALOX5 arachidonate 5-lipoxygenase
ALPPL2 alkaline phosphatase, placental-like 2
ARHGAP26 Rho GTPase activating protein 26
ARMC9 armadillo repeat containing 9
AURKA aurora kinase A
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BAAT bile acid CoA:amino acid N-acyltransferase
CA5B carbonic anhydrase VB, mitochondrial
CAPN9 calpain 9
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CDC14A cell division cycle 14A
CLDN11 claudin 11
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DCAF11 DDB1 and CUL4 associated factor 11
DGKA diacylglycerol kinase, alpha 80kDa
DMBT1 deleted in malignant brain tumors 1
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
ELSPBP1 epididymal sperm binding protein 1
EML2 echinoderm microtubule associated protein like 2
ENOX2 ecto-NOX disulfide-thiol exchanger 2
ESRRG estrogen-related receptor gamma
FDPS farnesyl diphosphate synthase
FRMD8 FERM domain containing 8
GFI1 growth factor independent 1 transcription repressor
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLRA3 glycine receptor, alpha 3
GOSR2 golgi SNAP receptor complex member 2
GTPBP1 GTP binding protein 1
HABP4 hyaluronan binding protein 4
HAPLN1 hyaluronan and proteoglycan link protein 1
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HNMT histamine N-methyltransferase
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
ICA1 islet cell autoantigen 1, 69kDa
ICOSLG inducible T-cell co-stimulator ligand
IFIH1 interferon induced with helicase C domain 1
IFT54 intraflagellar transport 54
IKZF5 IKAROS family zinc finger 5 (Pegasus)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KLHL25 kelch-like family member 25
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LARP7 La ribonucleoprotein domain family, member 7
LGALS8 lectin, galactoside-binding, soluble, 8
LINC00115 long intergenic non-protein coding RNA 115
MAN1C1 mannosidase, alpha, class 1C, member 1
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MED28 mediator complex subunit 28
NAV3 neuron navigator 3
NR2F6 nuclear receptor subfamily 2, group F, member 6
OR12D3 olfactory receptor, family 12, subfamily D, member 3
OR7E24 olfactory receptor, family 7, subfamily E, member 24
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PCNX pecanex homolog (Drosophila)
PDE4DIP phosphodiesterase 4D interacting protein
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PGPEP1 pyroglutamyl-peptidase I
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PYHIN1 pyrin and HIN domain family, member 1
RABGAP1 RAB GTPase activating protein 1
RPH3AL rabphilin 3A-like (without C2 domains)
S100A5 S100 calcium binding protein A5
SAA3P serum amyloid A3 pseudogene
SAMD4A sterile alpha motif domain containing 4A
SIDT2 SID1 transmembrane family, member 2
SIGLEC6 sialic acid binding Ig-like lectin 6
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SRCAP Snf2-related CREBBP activator protein
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
SULF1 sulfatase 1
TACR1 tachykinin receptor 1
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TONSL tonsoku-like, DNA repair protein
TPP1 tripeptidyl peptidase I
TSKS testis-specific serine kinase substrate
UPK2 uroplakin 2
VIPR2 vasoactive intestinal peptide receptor 2
WDR62 WD repeat domain 62
WNT2B wingless-type MMTV integration site family, member 2B
ZFPL1 zinc finger protein-like 1
ZNF117 zinc finger protein 117
ZNF214 zinc finger protein 214
ZNF219 zinc finger protein 219
ZNF675 zinc finger protein 675
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACADSB acyl-CoA dehydrogenase, short/branched chain
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ALS2CL ALS2 C-terminal like
AMH anti-Mullerian hormone
AMT aminomethyltransferase
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ANKRD36 ankyrin repeat domain 36
C16ORF59 chromosome 16 open reading frame 59
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD72 CD72 molecule
CENPJ centromere protein J
CIDEB cell death-inducing DFFA-like effector b
CISH cytokine inducible SH2-containing protein
CLEC10A C-type lectin domain family 10, member A
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COMP cartilage oligomeric matrix protein
COQ6 coenzyme Q6 monooxygenase
CRISP2 cysteine-rich secretory protein 2
CTSO cathepsin O
DEF6 differentially expressed in FDCP 6 homolog (mouse)
EHF ets homologous factor
ERAP2 endoplasmic reticulum aminopeptidase 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM110B family with sequence similarity 110, member B
FMO4 flavin containing monooxygenase 4
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRS3 fibroblast growth factor receptor substrate 3
GADD45G growth arrest and DNA-damage-inducible, gamma
GLS2 glutaminase 2 (liver, mitochondrial)
HAMP hepcidin antimicrobial peptide
HIST1H2AK histone cluster 1, H2ak
HIST1H3I histone cluster 1, H3i
HOXA1 homeobox A1
HOXA7 homeobox A7
ICOS inducible T-cell co-stimulator
IGSF3 immunoglobulin superfamily, member 3
IL11RA interleukin 11 receptor, alpha
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL32 interleukin 32
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KIAA1456 KIAA1456
LOC100127972 uncharacterized LOC100127972
MBTD1 mbt domain containing 1
MCPH1 microcephalin 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MTSS1L metastasis suppressor 1-like
MYOZ1 myozenin 1
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NDP Norrie disease (pseudoglioma)
NNAT neuronatin
NR1H4 nuclear receptor subfamily 1, group H, member 4
NRN1 neuritin 1
NT5M 5',3'-nucleotidase, mitochondrial
NTF3 neurotrophin 3
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSBP2 oxysterol binding protein 2
OSMR oncostatin M receptor
PAIP2B poly(A) binding protein interacting protein 2B
PDE8B phosphodiesterase 8B
PHC1 polyhomeotic homolog 1 (Drosophila)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLD2 phospholipase D2
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PRB3 proline-rich protein BstNI subfamily 3
PRDM14 PR domain containing 14
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRR14L proline rich 14-like
PTTG2 pituitary tumor-transforming 2
PWAR5 Prader Willi/Angelman region RNA 5
RAPSN receptor-associated protein of the synapse
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF126P1 ring finger protein 126 pseudogene 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SAMD9 sterile alpha motif domain containing 9
SCG5 secretogranin V
SCGB2A2 secretoglobin, family 2A, member 2
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEC14L2 SEC14-like 2 (S. cerevisiae)
SH2D4A SH2 domain containing 4A
SLC35F6 solute carrier family 35, member F6
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SNORA21 small nucleolar RNA, H/ACA box 21
SOX30 SRY (sex determining region Y)-box 30
ST5 suppression of tumorigenicity 5
SYNGR3 synaptogyrin 3
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
THBS3 thrombospondin 3
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TRIM21 tripartite motif containing 21
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
TXLNG taxilin gamma
WDR91 WD repeat domain 91
ZNF208 zinc finger protein 208
ZNF286A zinc finger protein 286A
ZNF606 zinc finger protein 606
ZNF711 zinc finger protein 711