| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the eticlopride-5695 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAMDC | adipogenesis associated, Mth938 domain containing |
| ADAM3A | ADAM metallopeptidase domain 3A (pseudogene) |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ATF3 | activating transcription factor 3 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 |
| C8A | complement component 8, alpha polypeptide |
| CABP1 | calcium binding protein 1 |
| CDC42 | cell division cycle 42 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| COL6A1 | collagen, type VI, alpha 1 |
| COPE | coatomer protein complex, subunit epsilon |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DCC | DCC netrin 1 receptor |
| DCT | dopachrome tautomerase |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DOPEY2 | dopey family member 2 |
| DRICH1 | aspartate-rich 1 |
| EGFR | epidermal growth factor receptor |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 |
| FAM65B | family with sequence similarity 65, member B |
| FGF1 | fibroblast growth factor 1 (acidic) |
| FGF18 | fibroblast growth factor 18 |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GLIPR1 | GLI pathogenesis-related 1 |
| GPR143 | G protein-coupled receptor 143 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) |
| GRM8 | glutamate receptor, metabotropic 8 |
| HAS2 | hyaluronan synthase 2 |
| HOXB2 | homeobox B2 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled |
| IFI16 | interferon, gamma-inducible protein 16 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| INHBE | inhibin, beta E |
| IRS2 | insulin receptor substrate 2 |
| ITGB7 | integrin, beta 7 |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LEFTY2 | left-right determination factor 2 |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| LOC79999 | uncharacterized LOC79999 |
| LOXL3 | lysyl oxidase-like 3 |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MCAM | melanoma cell adhesion molecule |
| MDFI | MyoD family inhibitor |
| MMP3 | matrix metallopeptidase 3 |
| MST1R | macrophage stimulating 1 receptor |
| MTMR8 | myotubularin related protein 8 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 |
| NFX1 | nuclear transcription factor, X-box binding 1 |
| NRSN2 | neurensin 2 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PAX8 | paired box 8 |
| PDAP1 | PDGFA associated protein 1 |
| PEX6 | peroxisomal biogenesis factor 6 |
| PHF7 | PHD finger protein 7 |
| PHKG1 | phosphorylase kinase, gamma 1 (muscle) |
| PLAG1 | pleiomorphic adenoma gene 1 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRDM9 | PR domain containing 9 |
| PRO2964 | uncharacterized protein PRO2964 |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| RBBP9 | retinoblastoma binding protein 9 |
| RGS1 | regulator of G-protein signaling 1 |
| RGS14 | regulator of G-protein signaling 14 |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| RUNX1 | runt-related transcription factor 1 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SATB1 | SATB homeobox 1 |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| SPHK2 | sphingosine kinase 2 |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| STRA6 | stimulated by retinoic acid 6 |
| SYK | spleen tyrosine kinase |
| SYP | synaptophysin |
| SYT2 | synaptotagmin II |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TNFSF11 | tumor necrosis factor (ligand) superfamily, member 11 |
| TRBC1 | T cell receptor beta constant 1 |
| TRIB2 | tribbles pseudokinase 2 |
| TSSK2 | testis-specific serine kinase 2 |
| UBXN1 | UBX domain protein 1 |
| VLDLR | very low density lipoprotein receptor |
| ZFHX2 | zinc finger homeobox 2 |
| ZFPL1 | zinc finger protein-like 1 |
| ZNF222 | zinc finger protein 222 |
| ZNF224 | zinc finger protein 224 |
| ZNF235 | zinc finger protein 235 |
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ALS2CL | ALS2 C-terminal like |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARRB2 | arrestin, beta 2 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BMP15 | bone morphogenetic protein 15 |
| BMP4 | bone morphogenetic protein 4 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CAPG | capping protein (actin filament), gelsolin-like |
| CASKIN2 | CASK interacting protein 2 |
| CCDC85C | coiled-coil domain containing 85C |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CHKB | choline kinase beta |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CLDN1 | claudin 1 |
| CNN2 | calponin 2 |
| CPTP | ceramide-1-phosphate transfer protein |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CXORF21 | chromosome X open reading frame 21 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DUSP2 | dual specificity phosphatase 2 |
| EN2 | engrailed homeobox 2 |
| EXOC6B | exocyst complex component 6B |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPR27 | G protein-coupled receptor 27 |
| GPR3 | G protein-coupled receptor 3 |
| GSTA4 | glutathione S-transferase alpha 4 |
| HDAC11 | histone deacetylase 11 |
| HOXA4 | homeobox A4 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI35 | interferon-induced protein 35 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| INCENP | inner centromere protein antigens 135/155kDa |
| INO80D | INO80 complex subunit D |
| IQCG | IQ motif containing G |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| JMJD4 | jumonji domain containing 4 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
| KIAA0319L | KIAA0319-like |
| KITLG | KIT ligand |
| LAMA3 | laminin, alpha 3 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LMNB1 | lamin B1 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LYRM9 | LYR motif containing 9 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MAP7D1 | MAP7 domain containing 1 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MMP2 | matrix metallopeptidase 2 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) |
| MRPL2 | mitochondrial ribosomal protein L2 |
| NDRG1 | N-myc downstream regulated 1 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| RAD51B | RAD51 paralog B |
| RNF39 | ring finger protein 39 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RPGRIP1L | RPGRIP1-like |
| RUSC2 | RUN and SH3 domain containing 2 |
| S100A4 | S100 calcium binding protein A4 |
| SDC3 | syndecan 3 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SP1 | Sp1 transcription factor |
| SPRYD7 | SPRY domain containing 7 |
| SYNC | syncoilin, intermediate filament protein |
| TDRD12 | tudor domain containing 12 |
| TEP1 | telomerase-associated protein 1 |
| TMEM104 | transmembrane protein 104 |
| TMEM209 | transmembrane protein 209 |
| TRABD | TraB domain containing |
| TREM1 | triggering receptor expressed on myeloid cells 1 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UBQLN4 | ubiquilin 4 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| ZNF16 | zinc finger protein 16 |
| ZNF324 | zinc finger protein 324 |
| ZNF35 | zinc finger protein 35 |
| ZNF552 | zinc finger protein 552 |
| ZNF696 | zinc finger protein 696 |