Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the etidronic acid-3325 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
ADGRE1 | adhesion G protein-coupled receptor E1 |
ADRA1A | adrenoceptor alpha 1A |
AHNAK2 | AHNAK nucleoprotein 2 |
APOH | apolipoprotein H (beta-2-glycoprotein I) |
ARR3 | arrestin 3, retinal (X-arrestin) |
ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
BGN | biglycan |
BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
CASP1 | caspase 1, apoptosis-related cysteine peptidase |
CD1A | CD1a molecule |
CDC42 | cell division cycle 42 |
CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
CEP112 | centrosomal protein 112kDa |
CNOT2 | CCR4-NOT transcription complex, subunit 2 |
CNR2 | cannabinoid receptor 2 (macrophage) |
COL3A1 | collagen, type III, alpha 1 |
CYB5A | cytochrome b5 type A (microsomal) |
DOK4 | docking protein 4 |
DPYS | dihydropyrimidinase |
EPHA3 | EPH receptor A3 |
FAXDC2 | fatty acid hydroxylase domain containing 2 |
FHL1 | four and a half LIM domains 1 |
FLJ42627 | uncharacterized LOC645644 |
FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
GRM1 | glutamate receptor, metabotropic 1 |
GRPR | gastrin-releasing peptide receptor |
HOXA2 | homeobox A2 |
HOXC4 | homeobox C4 |
HPCAL4 | hippocalcin like 4 |
ICA1 | islet cell autoantigen 1, 69kDa |
IL11 | interleukin 11 |
IL1B | interleukin 1, beta |
KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
KDM8 | lysine (K)-specific demethylase 8 |
LENEP | lens epithelial protein |
LGALS4 | lectin, galactoside-binding, soluble, 4 |
LOXL2 | lysyl oxidase-like 2 |
LRP12 | low density lipoprotein receptor-related protein 12 |
LRRTM2 | leucine rich repeat transmembrane neuronal 2 |
LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
MARK2 | MAP/microtubule affinity-regulating kinase 2 |
MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
MST1 | macrophage stimulating 1 |
MTAP | methylthioadenosine phosphorylase |
MUC3B | mucin 3B, cell surface associated |
MYBPC3 | myosin binding protein C, cardiac |
MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
MYF5 | myogenic factor 5 |
NAG18 | NAG18 mRNA |
NEK1 | NIMA-related kinase 1 |
NEUROD1 | neuronal differentiation 1 |
NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
NYNRIN | NYN domain and retroviral integrase containing |
OMG | oligodendrocyte myelin glycoprotein |
OR1E1 | olfactory receptor, family 1, subfamily E, member 1 |
OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
OTOR | otoraplin |
OXCT2 | 3-oxoacid CoA transferase 2 |
PCDHGA3 | protocadherin gamma subfamily A, 3 |
PDE3B | phosphodiesterase 3B, cGMP-inhibited |
PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
PRDM16 | PR domain containing 16 |
PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
RNF186 | ring finger protein 186 |
SAFB2 | scaffold attachment factor B2 |
SAMD9 | sterile alpha motif domain containing 9 |
SFTPB | surfactant protein B |
SH2D3A | SH2 domain containing 3A |
SIGLEC7 | sialic acid binding Ig-like lectin 7 |
SIRT5 | sirtuin 5 |
SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
SLC35E2 | solute carrier family 35, member E2 |
SLC43A3 | solute carrier family 43, member 3 |
SNCAIP | synuclein, alpha interacting protein |
SNX29P2 | sorting nexin 29 pseudogene 2 |
SPRR2B | small proline-rich protein 2B |
STRN3 | striatin, calmodulin binding protein 3 |
STYK1 | serine/threonine/tyrosine kinase 1 |
TAT | tyrosine aminotransferase |
TEX15 | testis expressed 15 |
TIMP3 | TIMP metallopeptidase inhibitor 3 |
TJAP1 | tight junction associated protein 1 (peripheral) |
TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
TPMT | thiopurine S-methyltransferase |
TRIL | TLR4 interactor with leucine-rich repeats |
TRIM29 | tripartite motif containing 29 |
UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 |
WAPAL | wings apart-like homolog (Drosophila) |
YPEL1 | yippee-like 1 (Drosophila) |
ZMAT4 | zinc finger, matrin-type 4 |
ZNF287 | zinc finger protein 287 |
ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
Symbol | Name |
---|---|
ACAD10 | acyl-CoA dehydrogenase family, member 10 |
ADGRE5 | adhesion G protein-coupled receptor E5 |
AKIP1 | A kinase (PRKA) interacting protein 1 |
ALG12 | ALG12, alpha-1,6-mannosyltransferase |
ALPK1 | alpha-kinase 1 |
ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
C4ORF29 | chromosome 4 open reading frame 29 |
CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
CAMTA1 | calmodulin binding transcription activator 1 |
CAPN15 | calpain 15 |
CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
CENPJ | centromere protein J |
CEP97 | centrosomal protein 97kDa |
CGREF1 | cell growth regulator with EF-hand domain 1 |
CIDEB | cell death-inducing DFFA-like effector b |
CLDN15 | claudin 15 |
COPZ2 | coatomer protein complex, subunit zeta 2 |
CORO7 | coronin 7 |
CXCL12 | chemokine (C-X-C motif) ligand 12 |
CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
DDIT3 | DNA-damage-inducible transcript 3 |
DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
EGR3 | early growth response 3 |
ETNK2 | ethanolamine kinase 2 |
FAM46C | family with sequence similarity 46, member C |
FBRS | fibrosin |
FLCN | folliculin |
GINS4 | GINS complex subunit 4 (Sld5 homolog) |
GMIP | GEM interacting protein |
GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
GSTCD | glutathione S-transferase, C-terminal domain containing |
GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
GUSBP3 | glucuronidase, beta pseudogene 3 |
HDAC7 | histone deacetylase 7 |
HIST1H2AL | histone cluster 1, H2al |
HIST1H4F | histone cluster 1, H4f |
HOXA4 | homeobox A4 |
HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
HYI | hydroxypyruvate isomerase (putative) |
IER3 | immediate early response 3 |
IGFBP4 | insulin-like growth factor binding protein 4 |
KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
KCTD7 | potassium channel tetramerization domain containing 7 |
KIAA0125 | KIAA0125 |
LAMB3 | laminin, beta 3 |
LRRC37A3 | leucine rich repeat containing 37, member A3 |
LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
MMP2 | matrix metallopeptidase 2 |
MSMB | microseminoprotein, beta- |
MYO9A | myosin IXA |
NPFFR1 | neuropeptide FF receptor 1 |
NPY1R | neuropeptide Y receptor Y1 |
NPY5R | neuropeptide Y receptor Y5 |
OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
PARD6A | par-6 family cell polarity regulator alpha |
PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
QPCTL | glutaminyl-peptide cyclotransferase-like |
RAB30 | RAB30, member RAS oncogene family |
RAD54L2 | RAD54-like 2 (S. cerevisiae) |
RAI14 | retinoic acid induced 14 |
RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
RHOBTB1 | Rho-related BTB domain containing 1 |
RPGRIP1L | RPGRIP1-like |
SCN1B | sodium channel, voltage gated, type I beta subunit |
SDC3 | syndecan 3 |
SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
SIRT2 | sirtuin 2 |
SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
SNORA21 | small nucleolar RNA, H/ACA box 21 |
SPINK4 | serine peptidase inhibitor, Kazal type 4 |
STARD13 | StAR-related lipid transfer (START) domain containing 13 |
STC2 | stanniocalcin 2 |
SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
SYBU | syntabulin (syntaxin-interacting) |
TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
TDRD1 | tudor domain containing 1 |
TH | tyrosine hydroxylase |
TMPRSS3 | transmembrane protease, serine 3 |
TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
TSKU | tsukushi, small leucine rich proteoglycan |
UNC119 | unc-119 homolog (C. elegans) |
URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
ZFHX3 | zinc finger homeobox 3 |
ZNF134 | zinc finger protein 134 |
ZNF652 | zinc finger protein 652 |
ZNF721 | zinc finger protein 721 |