Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the etidronic acid-4387 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACAN | aggrecan |
ADRA2B | adrenoceptor alpha 2B |
APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
ATP6AP2 | ATPase, H+ transporting, lysosomal accessory protein 2 |
B9D1 | B9 protein domain 1 |
BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
C1ORF21 | chromosome 1 open reading frame 21 |
CABP2 | calcium binding protein 2 |
CASP2 | caspase 2, apoptosis-related cysteine peptidase |
CCDC85B | coiled-coil domain containing 85B |
CCL19 | chemokine (C-C motif) ligand 19 |
CCL23 | chemokine (C-C motif) ligand 23 |
CCR8 | chemokine (C-C motif) receptor 8 |
CCRL2 | chemokine (C-C motif) receptor-like 2 |
CD40 | CD40 molecule, TNF receptor superfamily member 5 |
CFAP69 | cilia and flagella associated protein 69 |
CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
CKMT2 | creatine kinase, mitochondrial 2 (sarcomeric) |
COL4A1 | collagen, type IV, alpha 1 |
CPSF1 | cleavage and polyadenylation specific factor 1, 160kDa |
CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
CTNS | cystinosin, lysosomal cystine transporter |
CXCR2 | chemokine (C-X-C motif) receptor 2 |
CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
EDN1 | endothelin 1 |
EFR3B | EFR3 homolog B (S. cerevisiae) |
FGF18 | fibroblast growth factor 18 |
FRAS1 | Fraser extracellular matrix complex subunit 1 |
GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits |
GPD2 | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) |
GPR182 | G protein-coupled receptor 182 |
GPR85 | G protein-coupled receptor 85 |
GREB1L | growth regulation by estrogen in breast cancer-like |
HCRTR2 | hypocretin (orexin) receptor 2 |
HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
ICAM4 | intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) |
IFI27 | interferon, alpha-inducible protein 27 |
IFI6 | interferon, alpha-inducible protein 6 |
IFNA14 | interferon, alpha 14 |
IGLJ3 | immunoglobulin lambda joining 3 |
INHBE | inhibin, beta E |
IQCK | IQ motif containing K |
ITM2C | integral membrane protein 2C |
KIAA1109 | KIAA1109 |
KIDINS220 | kinase D-interacting substrate, 220kDa |
KIR2DL1 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 |
KLF12 | Kruppel-like factor 12 |
LAT2 | linker for activation of T cells family, member 2 |
LOC100286895 | cell division cycle 27 homolog pseudogene |
LRRC17 | leucine rich repeat containing 17 |
LSP1 | lymphocyte-specific protein 1 |
LY6G6C | lymphocyte antigen 6 complex, locus G6C |
MAOA | monoamine oxidase A |
MNDA | myeloid cell nuclear differentiation antigen |
NCAM1 | neural cell adhesion molecule 1 |
NID1 | nidogen 1 |
NIPAL3 | NIPA-like domain containing 3 |
OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
OSBPL3 | oxysterol binding protein-like 3 |
PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
PIP | prolactin-induced protein |
PLAT | plasminogen activator, tissue |
PLCE1 | phospholipase C, epsilon 1 |
PON3 | paraoxonase 3 |
PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
PRF1 | perforin 1 (pore forming protein) |
PRKCQ | protein kinase C, theta |
PTPN1 | protein tyrosine phosphatase, non-receptor type 1 |
RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
RIMS1 | regulating synaptic membrane exocytosis 1 |
SAA3P | serum amyloid A3 pseudogene |
SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 |
SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
SIGLEC7 | sialic acid binding Ig-like lectin 7 |
SLAMF7 | SLAM family member 7 |
SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
SNAP25 | synaptosomal-associated protein, 25kDa |
SNRPN | small nuclear ribonucleoprotein polypeptide N |
SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
SPN | sialophorin |
SRSF7 | serine/arginine-rich splicing factor 7 |
SSX3 | synovial sarcoma, X breakpoint 3 |
STS | steroid sulfatase (microsomal), isozyme S |
SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
TBX6 | T-box 6 |
TCF25 | transcription factor 25 (basic helix-loop-helix) |
TEX40 | testis expressed 40 |
THPO | thrombopoietin |
TONSL | tonsoku-like, DNA repair protein |
TRIM3 | tripartite motif containing 3 |
TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
XCR1 | chemokine (C motif) receptor 1 |
ZIM2 | zinc finger, imprinted 2 |
Symbol | Name |
---|---|
ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
ACSL4 | acyl-CoA synthetase long-chain family member 4 |
AHNAK2 | AHNAK nucleoprotein 2 |
AMT | aminomethyltransferase |
ANXA2P3 | annexin A2 pseudogene 3 |
AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
APLP1 | amyloid beta (A4) precursor-like protein 1 |
ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
ATAT1 | alpha tubulin acetyltransferase 1 |
BAX | BCL2-associated X protein |
C10ORF88 | chromosome 10 open reading frame 88 |
C11ORF30 | chromosome 11 open reading frame 30 |
C17ORF80 | chromosome 17 open reading frame 80 |
C19ORF73 | chromosome 19 open reading frame 73 |
C1ORF54 | chromosome 1 open reading frame 54 |
C3 | complement component 3 |
CALML5 | calmodulin-like 5 |
CAMK1 | calcium/calmodulin-dependent protein kinase I |
CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
CCDC121 | coiled-coil domain containing 121 |
CCDC64 | coiled-coil domain containing 64 |
CCDC69 | coiled-coil domain containing 69 |
CCP110 | centriolar coiled coil protein 110kDa |
CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
CDHR2 | cadherin-related family member 2 |
CHKB | choline kinase beta |
CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
CLDN1 | claudin 1 |
CLSTN2 | calsyntenin 2 |
CNTN1 | contactin 1 |
CORO7 | coronin 7 |
CTSF | cathepsin F |
CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
CYP2W1 | cytochrome P450, family 2, subfamily W, polypeptide 1 |
DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
EDAR | ectodysplasin A receptor |
EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
ETAA1 | Ewing tumor-associated antigen 1 |
EXOC6B | exocyst complex component 6B |
F2R | coagulation factor II (thrombin) receptor |
FAM120C | family with sequence similarity 120C |
FAM169A | family with sequence similarity 169, member A |
GADD45G | growth arrest and DNA-damage-inducible, gamma |
GDAP1 | ganglioside induced differentiation associated protein 1 |
GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
GPC3 | glypican 3 |
GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
HDAC5 | histone deacetylase 5 |
HIRA | histone cell cycle regulator |
HIST1H1D | histone cluster 1, H1d |
HIST1H3E | histone cluster 1, H3e |
HIST1H4C | histone cluster 1, H4c |
HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
KIAA0319L | KIAA0319-like |
KIAA0754 | KIAA0754 |
KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
KPNA5 | karyopherin alpha 5 (importin alpha 6) |
LINC00597 | long intergenic non-protein coding RNA 597 |
LMNB1 | lamin B1 |
MDM4 | MDM4, p53 regulator |
MMP9 | matrix metallopeptidase 9 |
MRPL41 | mitochondrial ribosomal protein L41 |
MTA2 | metastasis associated 1 family, member 2 |
MX2 | MX dynamin-like GTPase 2 |
NEUROD1 | neuronal differentiation 1 |
NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
NPY4R | neuropeptide Y receptor Y4 |
PCDHA6 | protocadherin alpha 6 |
PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
PORCN | porcupine homolog (Drosophila) |
PYCRL | pyrroline-5-carboxylate reductase-like |
RAB36 | RAB36, member RAS oncogene family |
RAB5B | RAB5B, member RAS oncogene family |
RNF39 | ring finger protein 39 |
RORC | RAR-related orphan receptor C |
RPL10L | ribosomal protein L10-like |
SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
SLC38A10 | solute carrier family 38, member 10 |
SPINK4 | serine peptidase inhibitor, Kazal type 4 |
STX1A | syntaxin 1A (brain) |
TBC1D2 | TBC1 domain family, member 2 |
TCP10 | t-complex 10 |
TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
TPSG1 | tryptase gamma 1 |
TRAF3IP1 | TNF receptor-associated factor 3 interacting protein 1 |
TSPYL2 | TSPY-like 2 |
USP20 | ubiquitin specific peptidase 20 |
VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
ZBTB48 | zinc finger and BTB domain containing 48 |
ZNF492 | zinc finger protein 492 |
ZNF747 | zinc finger protein 747 |
ZNF750 | zinc finger protein 750 |
ZNF76 | zinc finger protein 76 |
ZNF768 | zinc finger protein 768 |
ZNF816 | zinc finger protein 816 |