etifenin-2477 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the etifenin-2477 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACTA1 actin, alpha 1, skeletal muscle
ADCK4 aarF domain containing kinase 4
ADORA1 adenosine A1 receptor
AFF2 AF4/FMR2 family, member 2
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ATAT1 alpha tubulin acetyltransferase 1
BMP7 bone morphogenetic protein 7
BTN2A3P butyrophilin, subfamily 2, member A3, pseudogene
C1QTNF1 C1q and tumor necrosis factor related protein 1
CCSER2 coiled-coil serine-rich protein 2
CD8B CD8b molecule
CDC42 cell division cycle 42
CDON cell adhesion associated, oncogene regulated
CLMN calmin (calponin-like, transmembrane)
CNPY4 canopy FGF signaling regulator 4
CRABP2 cellular retinoic acid binding protein 2
CREM cAMP responsive element modulator
CRYGD crystallin, gamma D
CTAG2 cancer/testis antigen 2
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
EPHA5 EPH receptor A5
EPN1 epsin 1
FBXO2 F-box protein 2
FER fer (fps/fes related) tyrosine kinase
FLOT1 flotillin 1
FZD4 frizzled class receptor 4
GAA glucosidase, alpha; acid
GK2 glycerol kinase 2
GRHL2 grainyhead-like 2 (Drosophila)
GSK3A glycogen synthase kinase 3 alpha
GUCY2F guanylate cyclase 2F, retinal
GZMK granzyme K (granzyme 3; tryptase II)
HDLBP high density lipoprotein binding protein
HOXA6 homeobox A6
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IGF1R insulin-like growth factor 1 receptor
IGHM immunoglobulin heavy constant mu
IHH indian hedgehog
INHBA inhibin, beta A
KCTD2 potassium channel tetramerization domain containing 2
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLHL36 kelch-like family member 36
LTBP2 latent transforming growth factor beta binding protein 2
MAP4 microtubule-associated protein 4
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MEF2C myocyte enhancer factor 2C
MFSD7 major facilitator superfamily domain containing 7
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MYOZ3 myozenin 3
NCKIPSD NCK interacting protein with SH3 domain
NCLN nicalin
NEUROD4 neuronal differentiation 4
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NPPA natriuretic peptide A
NPY6R neuropeptide Y receptor Y6 (pseudogene)
OLFML2B olfactomedin-like 2B
PAIP2B poly(A) binding protein interacting protein 2B
PCSK6 proprotein convertase subtilisin/kexin type 6
PGLYRP4 peptidoglycan recognition protein 4
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PML promyelocytic leukemia
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRKCE protein kinase C, epsilon
PTCRA pre T-cell antigen receptor alpha
RAB11B RAB11B, member RAS oncogene family
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RANBP1 RAN binding protein 1
RASAL1 RAS protein activator like 1 (GAP1 like)
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
REPS1 RALBP1 associated Eps domain containing 1
RGS12 regulator of G-protein signaling 12
RTEL1 regulator of telomere elongation helicase 1
SAA4 serum amyloid A4, constitutive
SBNO2 strawberry notch homolog 2 (Drosophila)
SEZ6L seizure related 6 homolog (mouse)-like
SH3PXD2A SH3 and PX domains 2A
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC12A8 solute carrier family 12, member 8
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC39A9 solute carrier family 39, member 9
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SOCS2 suppressor of cytokine signaling 2
SPDEF SAM pointed domain containing ETS transcription factor
SSPN sarcospan
TBC1D2 TBC1 domain family, member 2
TCP10L t-complex 10-like
TCP11L1 t-complex 11, testis-specific-like 1
TEF thyrotrophic embryonic factor
TLR5 toll-like receptor 5
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TUBG2 tubulin, gamma 2
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF280A zinc finger protein 280A

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ADAM15 ADAM metallopeptidase domain 15
ADGRE2 adhesion G protein-coupled receptor E2
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
AMDHD2 amidohydrolase domain containing 2
ANXA2P2 annexin A2 pseudogene 2
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
ARL15 ADP-ribosylation factor-like 15
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BIK BCL2-interacting killer (apoptosis-inducing)
C16ORF59 chromosome 16 open reading frame 59
C22ORF29 chromosome 22 open reading frame 29
C9ORF3 chromosome 9 open reading frame 3
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDCP1 CUB domain containing protein 1
CHM choroideremia (Rab escort protein 1)
CLCN2 chloride channel, voltage-sensitive 2
CORT cortistatin
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DOCK4 dedicator of cytokinesis 4
DOK5 docking protein 5
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM188A family with sequence similarity 188, member A
FAM214B family with sequence similarity 214, member B
FKBP5 FK506 binding protein 5
G0S2 G0/G1 switch 2
GALK1 galactokinase 1
GK3P glycerol kinase 3 pseudogene
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GRIP2 glutamate receptor interacting protein 2
HIST1H1E histone cluster 1, H1e
HIST1H3B histone cluster 1, H3b
HRH2 histamine receptor H2
ICAM5 intercellular adhesion molecule 5, telencephalin
IL22 interleukin 22
INO80D INO80 complex subunit D
IQCG IQ motif containing G
IRS1 insulin receptor substrate 1
KCTD7 potassium channel tetramerization domain containing 7
KIAA1107 KIAA1107
KLHL28 kelch-like family member 28
LNPEP leucyl/cystinyl aminopeptidase
LYPLA2P1 lysophospholipase II pseudogene 1
MCTP2 multiple C2 domains, transmembrane 2
MDM4 MDM4, p53 regulator
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MIR22HG MIR22 host gene
MPZ myelin protein zero
MRAS muscle RAS oncogene homolog
MRPL52 mitochondrial ribosomal protein L52
NABP1 nucleic acid binding protein 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOL10 nucleolar protein 10
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PCDHGB5 protocadherin gamma subfamily B, 5
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PGM3 phosphoglucomutase 3
PHACTR1 phosphatase and actin regulator 1
PLCD1 phospholipase C, delta 1
PMCH pro-melanin-concentrating hormone
PODXL2 podocalyxin-like 2
POLL polymerase (DNA directed), lambda
PQLC2 PQ loop repeat containing 2
PRRC1 proline-rich coiled-coil 1
QTRT1 queuine tRNA-ribosyltransferase 1
RAB33A RAB33A, member RAS oncogene family
RABL6 RAB, member RAS oncogene family-like 6
RAP1GAP2 RAP1 GTPase activating protein 2
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RIN1 Ras and Rab interactor 1
SFT2D2 SFT2 domain containing 2
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STIM1 stromal interaction molecule 1
SURF2 surfeit 2
SYNC syncoilin, intermediate filament protein
TEP1 telomerase-associated protein 1
TIAM2 T-cell lymphoma invasion and metastasis 2
TLR8 toll-like receptor 8
TMC7 transmembrane channel-like 7
TRIM25 tripartite motif containing 25
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TSC22D4 TSC22 domain family, member 4
TSPAN13 tetraspanin 13
TSPAN32 tetraspanin 32
UPB1 ureidopropionase, beta
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
ZNF225 zinc finger protein 225
ZNF668 zinc finger protein 668