etifenin-2838 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the etifenin-2838 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACSL5 acyl-CoA synthetase long-chain family member 5
ADAM19 ADAM metallopeptidase domain 19
ADAM22 ADAM metallopeptidase domain 22
ADAP2 ArfGAP with dual PH domains 2
ADGRG1 adhesion G protein-coupled receptor G1
ATF7IP activating transcription factor 7 interacting protein
ATM ATM serine/threonine kinase
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
BAIAP3 BAI1-associated protein 3
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C10ORF95 chromosome 10 open reading frame 95
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CAPN15 calpain 15
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCDC134 coiled-coil domain containing 134
CD247 CD247 molecule
CFLAR CASP8 and FADD-like apoptosis regulator
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DST dystonin
EIF1 eukaryotic translation initiation factor 1
EML2 echinoderm microtubule associated protein like 2
EPN2 epsin 2
FFAR2 free fatty acid receptor 2
FGD1 FYVE, RhoGEF and PH domain containing 1
FGF5 fibroblast growth factor 5
FGFR1 fibroblast growth factor receptor 1
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GUSBP3 glucuronidase, beta pseudogene 3
HDAC7 histone deacetylase 7
HFE hemochromatosis
HIST1H2BN histone cluster 1, H2bn
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IRF6 interferon regulatory factor 6
IRS2 insulin receptor substrate 2
ITPK1 inositol-tetrakisphosphate 1-kinase
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
JAK2 Janus kinase 2
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KDM4B lysine (K)-specific demethylase 4B
KDM8 lysine (K)-specific demethylase 8
KRT38 keratin 38, type I
LGALS9 lectin, galactoside-binding, soluble, 9
MAOB monoamine oxidase B
MED18 mediator complex subunit 18
METTL7A methyltransferase like 7A
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MNMIP1 manchette microtubule inner protein 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MST1 macrophage stimulating 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
N4BP1 NEDD4 binding protein 1
NOD1 nucleotide-binding oligomerization domain containing 1
NPFFR1 neuropeptide FF receptor 1
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
PARD6B par-6 family cell polarity regulator beta
PDLIM7 PDZ and LIM domain 7 (enigma)
PGLYRP4 peptidoglycan recognition protein 4
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PKP2 plakophilin 2
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PPARD peroxisome proliferator-activated receptor delta
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PSG6 pregnancy specific beta-1-glycoprotein 6
RABGAP1 RAB GTPase activating protein 1
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RNF122 ring finger protein 122
RNF19B ring finger protein 19B
RNFT1 ring finger protein, transmembrane 1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SH3BP2 SH3-domain binding protein 2
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
STK17B serine/threonine kinase 17b
STS steroid sulfatase (microsomal), isozyme S
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TNK2 tyrosine kinase, non-receptor, 2
TSPAN5 tetraspanin 5
UBE3A ubiquitin protein ligase E3A
UBQLN4 ubiquilin 4
USP34 ubiquitin specific peptidase 34
WIZ widely interspaced zinc finger motifs
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
YIPF4 Yip1 domain family, member 4
ZFYVE9 zinc finger, FYVE domain containing 9
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF484 zinc finger protein 484
ZNF652 zinc finger protein 652
ZNF804A zinc finger protein 804A

decreased expression

Symbol Name
ACYP2 acylphosphatase 2, muscle type
AGO1 argonaute RISC catalytic component 1
AP1B1 adaptor-related protein complex 1, beta 1 subunit
ARHGAP10 Rho GTPase activating protein 10
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATP13A2 ATPase type 13A2
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BCOR BCL6 corepressor
BHLHB9 basic helix-loop-helix domain containing, class B, 9
CASP3 caspase 3, apoptosis-related cysteine peptidase
CEP170B centrosomal protein 170B
CEP72 centrosomal protein 72kDa
CGREF1 cell growth regulator with EF-hand domain 1
CLCF1 cardiotrophin-like cytokine factor 1
CLCN2 chloride channel, voltage-sensitive 2
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DMXL1 Dmx-like 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EHMT1 euchromatic histone-lysine N-methyltransferase 1
FAAH fatty acid amide hydrolase
FAM192A family with sequence similarity 192, member A
FAM53B family with sequence similarity 53, member B
FBXL2 F-box and leucine-rich repeat protein 2
FCHO1 FCH domain only 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPATCH2L G patch domain containing 2-like
HDAC11 histone deacetylase 11
HIST1H2AJ histone cluster 1, H2aj
HIST1H4D histone cluster 1, H4d
HSPA1L heat shock 70kDa protein 1-like
HYI hydroxypyruvate isomerase (putative)
ICK intestinal cell (MAK-like) kinase
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IP6K1 inositol hexakisphosphate kinase 1
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KIF13B kinesin family member 13B
KLHL25 kelch-like family member 25
LINC00115 long intergenic non-protein coding RNA 115
LINC00339 long intergenic non-protein coding RNA 339
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC37A2 leucine rich repeat containing 37, member A2
LRRC61 leucine rich repeat containing 61
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAST3 microtubule associated serine/threonine kinase 3
MBNL3 muscleblind-like splicing regulator 3
MCOLN3 mucolipin 3
METTL16 methyltransferase like 16
MFAP2 microfibrillar-associated protein 2
MNX1 motor neuron and pancreas homeobox 1
MTG1 mitochondrial ribosome-associated GTPase 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NRGN neurogranin (protein kinase C substrate, RC3)
NT5E 5'-nucleotidase, ecto (CD73)
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
PCBP4 poly(rC) binding protein 4
PLA2G12A phospholipase A2, group XIIA
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PNPLA6 patatin-like phospholipase domain containing 6
POR P450 (cytochrome) oxidoreductase
RAD54L RAD54-like (S. cerevisiae)
RNF2 ring finger protein 2
RPAP2 RNA polymerase II associated protein 2
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SIDT1 SID1 transmembrane family, member 1
SLC12A8 solute carrier family 12, member 8
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SMG9 SMG9 nonsense mediated mRNA decay factor
SNX15 sorting nexin 15
SPAG4 sperm associated antigen 4
SPIDR scaffolding protein involved in DNA repair
SPINK4 serine peptidase inhibitor, Kazal type 4
STBD1 starch binding domain 1
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TAGLN transgelin
TARBP2 TAR (HIV-1) RNA binding protein 2
TMEM115 transmembrane protein 115
TMEM254 transmembrane protein 254
TMUB2 transmembrane and ubiquitin-like domain containing 2
TRIM5 tripartite motif containing 5
TTLL1 tubulin tyrosine ligase-like family member 1
TUBG2 tubulin, gamma 2
VWA1 von Willebrand factor A domain containing 1
WDR91 WD repeat domain 91
YEATS4 YEATS domain containing 4
ZBTB39 zinc finger and BTB domain containing 39
ZBTB48 zinc finger and BTB domain containing 48
ZSCAN31 zinc finger and SCAN domain containing 31