etifenin-3998 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the etifenin-3998 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM7 ADAM metallopeptidase domain 7
AKR1C4 aldo-keto reductase family 1, member C4
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F
BET1L Bet1 golgi vesicular membrane trafficking protein-like
C10ORF12 chromosome 10 open reading frame 12
C19ORF57 chromosome 19 open reading frame 57
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CALD1 caldesmon 1
CALHM2 calcium homeostasis modulator 2
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCDC132 coiled-coil domain containing 132
CDC42 cell division cycle 42
CDC5L cell division cycle 5-like
CDK20 cyclin-dependent kinase 20
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEP162 centrosomal protein 162kDa
CIC capicua transcriptional repressor
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DDO D-aspartate oxidase
DNASE1L3 deoxyribonuclease I-like 3
DOCK3 dedicator of cytokinesis 3
DPF3 D4, zinc and double PHD fingers, family 3
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
F13B coagulation factor XIII, B polypeptide
FAM212B family with sequence similarity 212, member B
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FUZ fuzzy planar cell polarity protein
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GAL3ST4 galactose-3-O-sulfotransferase 4
GC group-specific component (vitamin D binding protein)
GJA4 gap junction protein, alpha 4, 37kDa
GPR183 G protein-coupled receptor 183
GPR37L1 G protein-coupled receptor 37 like 1
GSK3A glycogen synthase kinase 3 alpha
HBB hemoglobin, beta
HIPK3 homeodomain interacting protein kinase 3
HIST1H2BL histone cluster 1, H2bl
HOXA4 homeobox A4
IL1RN interleukin 1 receptor antagonist
IL5RA interleukin 5 receptor, alpha
INHBE inhibin, beta E
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB8 integrin, beta 8
KANSL3 KAT8 regulatory NSL complex subunit 3
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LAMA4 laminin, alpha 4
LINC00115 long intergenic non-protein coding RNA 115
LINC00652 long intergenic non-protein coding RNA 652
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
MMP13 matrix metallopeptidase 13
MORC1 MORC family CW-type zinc finger 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NCAM1 neural cell adhesion molecule 1
NOTCH3 notch 3
NRG1 neuregulin 1
NTF3 neurotrophin 3
OR10H1 olfactory receptor, family 10, subfamily H, member 1
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PLA2G5 phospholipase A2, group V
PPARD peroxisome proliferator-activated receptor delta
PRDM14 PR domain containing 14
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RASAL2 RAS protein activator like 2
RFXAP regulatory factor X-associated protein
RIMS3 regulating synaptic membrane exocytosis 3
RNF208 ring finger protein 208
RPS4Y1 ribosomal protein S4, Y-linked 1
SCGB2A1 secretoglobin, family 2A, member 1
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SRSF6 serine/arginine-rich splicing factor 6
STAT2 signal transducer and activator of transcription 2, 113kDa
SYT2 synaptotagmin II
TAGLN transgelin
TAPT1 transmembrane anterior posterior transformation 1
TBC1D2 TBC1 domain family, member 2
TECTA tectorin alpha
TFCP2L1 transcription factor CP2-like 1
TG thyroglobulin
TLE2 transducin-like enhancer of split 2
TLK1 tousled-like kinase 1
TOX thymocyte selection-associated high mobility group box
TRD T cell receptor delta locus
TSPAN8 tetraspanin 8
TTC30A tetratricopeptide repeat domain 30A
TTN titin
XIST X inactive specific transcript (non-protein coding)
XYLB xylulokinase homolog (H. influenzae)
YTHDC2 YTH domain containing 2
ZNF362 zinc finger protein 362
ZNF609 zinc finger protein 609
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ANKRD11 ankyrin repeat domain 11
ANKRD36B ankyrin repeat domain 36B
ASAP1-IT1 ASAP1 intronic transcript 1
BARD1 BRCA1 associated RING domain 1
BBX bobby sox homolog (Drosophila)
C1ORF56 chromosome 1 open reading frame 56
CCDC15 coiled-coil domain containing 15
CCNT1 cyclin T1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLDN14 claudin 14
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CPEB1 cytoplasmic polyadenylation element binding protein 1
CRELD1 cysteine-rich with EGF-like domains 1
CUEDC1 CUE domain containing 1
DCAF13 DDB1 and CUL4 associated factor 13
DCAF16 DDB1 and CUL4 associated factor 16
DCBLD2 discoidin, CUB and LCCL domain containing 2
DEPDC1 DEP domain containing 1
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM169A family with sequence similarity 169, member A
FBXW12 F-box and WD repeat domain containing 12
FER fer (fps/fes related) tyrosine kinase
FKSG49 FKSG49
FOXO3 forkhead box O3
GAREM GRB2 associated, regulator of MAPK1
GRB2 growth factor receptor-bound protein 2
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
HELLS helicase, lymphoid-specific
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFT22 intraflagellar transport 22
IL7R interleukin 7 receptor
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KIRREL kin of IRRE like (Drosophila)
LOC100272216 uncharacterized LOC100272216
LRP6 low density lipoprotein receptor-related protein 6
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP9 microtubule-associated protein 9
MAVS mitochondrial antiviral signaling protein
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCM3AP-AS1 MCM3AP antisense RNA 1
MCOLN1 mucolipin 1
MED1 mediator complex subunit 1
MIS18BP1 MIS18 binding protein 1
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NINL ninein-like
NR1D2 nuclear receptor subfamily 1, group D, member 2
PCYOX1 prenylcysteine oxidase 1
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
POLH polymerase (DNA directed), eta
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PTCD2 pentatricopeptide repeat domain 2
PTGFR prostaglandin F receptor (FP)
RBM41 RNA binding motif protein 41
RNF25 ring finger protein 25
RPL13P5 ribosomal protein L13 pseudogene 5
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RSRC1 arginine/serine-rich coiled-coil 1
SCYL2 SCY1-like 2 (S. cerevisiae)
SETD6 SET domain containing 6
SKI SKI proto-oncogene
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLIT2 slit homolog 2 (Drosophila)
SMAD5 SMAD family member 5
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SPIN1 spindlin 1
SYNJ2BP synaptojanin 2 binding protein
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THOC2 THO complex 2
TMEM260 transmembrane protein 260
TSPAN5 tetraspanin 5
TTBK2 tau tubulin kinase 2
UBE2W ubiquitin-conjugating enzyme E2W (putative)
UGCG UDP-glucose ceramide glucosyltransferase
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZBTB38 zinc finger and BTB domain containing 38
ZNF12 zinc finger protein 12
ZNF148 zinc finger protein 148
ZNF264 zinc finger protein 264
ZNF37BP zinc finger protein 37B, pseudogene
ZNF430 zinc finger protein 430
ZNF654 zinc finger protein 654
ZNF675 zinc finger protein 675
ZNF770 zinc finger protein 770
ZNF91 zinc finger protein 91
ZWILCH zwilch kinetochore protein