etifenin-4117 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the etifenin-4117 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTN2 actinin, alpha 2
AKAP7 A kinase (PRKA) anchor protein 7
APOLD1 apolipoprotein L domain containing 1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
C11ORF1 chromosome 11 open reading frame 1
C17ORF53 chromosome 17 open reading frame 53
C2ORF27A chromosome 2 open reading frame 27A
C4BPA complement component 4 binding protein, alpha
CAMK4 calcium/calmodulin-dependent protein kinase IV
CASQ2 calsequestrin 2 (cardiac muscle)
CBX8 chromobox homolog 8
CCDC28B coiled-coil domain containing 28B
CLEC5A C-type lectin domain family 5, member A
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL1A1 collagen, type I, alpha 1
CYLD cylindromatosis (turban tumor syndrome)
DAPK3 death-associated protein kinase 3
DFNB31 deafness, autosomal recessive 31
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ELSPBP1 epididymal sperm binding protein 1
EMP1 epithelial membrane protein 1
EPHB1 EPH receptor B1
FAM214B family with sequence similarity 214, member B
FBLN1 fibulin 1
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FLOT1 flotillin 1
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPATCH4 G patch domain containing 4
GPR143 G protein-coupled receptor 143
HIGD2A HIG1 hypoxia inducible domain family, member 2A
HIST1H2BI histone cluster 1, H2bi
HOXA4 homeobox A4
ICA1 islet cell autoantigen 1, 69kDa
IGFBP5 insulin-like growth factor binding protein 5
IGFBP6 insulin-like growth factor binding protein 6
ING1 inhibitor of growth family, member 1
IPW imprinted in Prader-Willi syndrome (non-protein coding)
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KEL Kell blood group, metallo-endopeptidase
KIAA1107 KIAA1107
LAMP1 lysosomal-associated membrane protein 1
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAGEA6 melanoma antigen family A6
MAPKBP1 mitogen-activated protein kinase binding protein 1
MFSD7 major facilitator superfamily domain containing 7
MID1 midline 1
MSI1 musashi RNA-binding protein 1
MUC3B mucin 3B, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYB v-myb avian myeloblastosis viral oncogene homolog
MYBPC3 myosin binding protein C, cardiac
MYOF myoferlin
NR2E3 nuclear receptor subfamily 2, group E, member 3
NR6A1 nuclear receptor subfamily 6, group A, member 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OLFM1 olfactomedin 1
OMG oligodendrocyte myelin glycoprotein
OSBPL7 oxysterol binding protein-like 7
PIAS1 protein inhibitor of activated STAT, 1
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PLSCR3 phospholipid scramblase 3
PLXNA3 plexin A3
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
RBMS2 RNA binding motif, single stranded interacting protein 2
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RPL10 ribosomal protein L10
RPS4Y1 ribosomal protein S4, Y-linked 1
RUNX1 runt-related transcription factor 1
S100A13 S100 calcium binding protein A13
S100A7 S100 calcium binding protein A7
SEPP1 selenoprotein P, plasma, 1
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SFTPB surfactant protein B
SH3BP2 SH3-domain binding protein 2
SHOX2 short stature homeobox 2
SKI SKI proto-oncogene
SLC35E2 solute carrier family 35, member E2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNX29 sorting nexin 29
SUGP1 SURP and G patch domain containing 1
SV2B synaptic vesicle glycoprotein 2B
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYK spleen tyrosine kinase
SYNJ2 synaptojanin 2
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
TCP11L1 t-complex 11, testis-specific-like 1
TFEB transcription factor EB
TIMP3 TIMP metallopeptidase inhibitor 3
TMCC2 transmembrane and coiled-coil domain family 2
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TUBA3D tubulin, alpha 3d
VAMP5 vesicle-associated membrane protein 5

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACVR2B activin A receptor, type IIB
ADGRE5 adhesion G protein-coupled receptor E5
ALG12 ALG12, alpha-1,6-mannosyltransferase
AOC2 amine oxidase, copper containing 2 (retina-specific)
BBC3 BCL2 binding component 3
C11ORF30 chromosome 11 open reading frame 30
C9ORF9 chromosome 9 open reading frame 9
CD82 CD82 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CHML choroideremia-like (Rab escort protein 2)
CLSPN claspin
CRMP1 collapsin response mediator protein 1
CYHR1 cysteine/histidine-rich 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DOK5 docking protein 5
DVL1 dishevelled segment polarity protein 1
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ELP3 elongator acetyltransferase complex subunit 3
ERCC4 excision repair cross-complementation group 4
FLJ21369 uncharacterized protein FLJ21369
FMOD fibromodulin
FURIN furin (paired basic amino acid cleaving enzyme)
GAMT guanidinoacetate N-methyltransferase
GEMIN8 gem (nuclear organelle) associated protein 8
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPR87 G protein-coupled receptor 87
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H1D histone cluster 1, H1d
HMOX1 heme oxygenase 1
HOOK1 hook microtubule-tethering protein 1
HP1BP3 heterochromatin protein 1, binding protein 3
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
HYI hydroxypyruvate isomerase (putative)
IFI6 interferon, alpha-inducible protein 6
IFT140 intraflagellar transport 140
INPP5J inositol polyphosphate-5-phosphatase J
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KDM5C lysine (K)-specific demethylase 5C
LPPR1 lipid phosphate phosphatase-related protein type 1
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MVD mevalonate (diphospho) decarboxylase
MYL5 myosin, light chain 5, regulatory
NAG18 NAG18 mRNA
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NKAIN1 Na+/K+ transporting ATPase interacting 1
NPY4R neuropeptide Y receptor Y4
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OSGIN1 oxidative stress induced growth inhibitor 1
OSMR oncostatin M receptor
PDE8B phosphodiesterase 8B
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PROL1 proline rich, lacrimal 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RAB3D RAB3D, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RCAN3 RCAN family member 3
RNF122 ring finger protein 122
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPL23AP32 ribosomal protein L23a pseudogene 32
RUSC2 RUN and SH3 domain containing 2
SAMD9 sterile alpha motif domain containing 9
SETD1A SET domain containing 1A
SLC16A6 solute carrier family 16, member 6
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SP1 Sp1 transcription factor
SPRYD7 SPRY domain containing 7
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TEP1 telomerase-associated protein 1
TPCN1 two pore segment channel 1
TRIM16 tripartite motif containing 16
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBQLN4 ubiquilin 4
UNC93B1 unc-93 homolog B1 (C. elegans)
VIPR1 vasoactive intestinal peptide receptor 1
VWA1 von Willebrand factor A domain containing 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF219 zinc finger protein 219
ZNF430 zinc finger protein 430
ZNF446 zinc finger protein 446
ZNF652 zinc finger protein 652
ZNF747 zinc finger protein 747