| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the etilefrine-2930 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ACTN2 | actinin, alpha 2 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ALOX12 | arachidonate 12-lipoxygenase |
| ANGPTL2 | angiopoietin-like 2 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 |
| AREG | amphiregulin |
| AXL | AXL receptor tyrosine kinase |
| BIN1 | bridging integrator 1 |
| BMP6 | bone morphogenetic protein 6 |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CD86 | CD86 molecule |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CDCP1 | CUB domain containing protein 1 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
| CENPO | centromere protein O |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CPA4 | carboxypeptidase A4 |
| CREM | cAMP responsive element modulator |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa |
| CXCL13 | chemokine (C-X-C motif) ligand 13 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DCSTAMP | dendrocyte expressed seven transmembrane protein |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DOCK4 | dedicator of cytokinesis 4 |
| DPEP2 | dipeptidase 2 |
| DRD2 | dopamine receptor D2 |
| E2F1 | E2F transcription factor 1 |
| EPHB3 | EPH receptor B3 |
| FADS3 | fatty acid desaturase 3 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FCAR | Fc fragment of IgA receptor |
| FLJ42627 | uncharacterized LOC645644 |
| FRZB | frizzled-related protein |
| FTH1 | ferritin, heavy polypeptide 1 |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| GRIP2 | glutamate receptor interacting protein 2 |
| HBP1 | HMG-box transcription factor 1 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IKBKAP | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein |
| IL1B | interleukin 1, beta |
| IL24 | interleukin 24 |
| IQSEC1 | IQ motif and Sec7 domain 1 |
| KIAA0226L | KIAA0226-like |
| KLHL22 | kelch-like family member 22 |
| KYNU | kynureninase |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LAMB3 | laminin, beta 3 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LPP | LIM domain containing preferred translocation partner in lipoma |
| LRRC6 | leucine rich repeat containing 6 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAP4 | microtubule-associated protein 4 |
| MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MLXIP | MLX interacting protein |
| MPDZ | multiple PDZ domain protein |
| MUC3A | mucin 3A, cell surface associated |
| NDE1 | nudE neurodevelopment protein 1 |
| NF2 | neurofibromin 2 (merlin) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NIPAL2 | NIPA-like domain containing 2 |
| NPTXR | neuronal pentraxin receptor |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B |
| RASAL2 | RAS protein activator like 2 |
| REC8 | REC8 meiotic recombination protein |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SDC2 | syndecan 2 |
| SH2D2A | SH2 domain containing 2A |
| SHOX2 | short stature homeobox 2 |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SP140 | SP140 nuclear body protein |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 |
| TAPBP | TAP binding protein (tapasin) |
| TBCD | tubulin folding cofactor D |
| TEX40 | testis expressed 40 |
| TGFB1 | transforming growth factor, beta 1 |
| THBS1 | thrombospondin 1 |
| TKTL1 | transketolase-like 1 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TRIM62 | tripartite motif containing 62 |
| UGT8 | UDP glycosyltransferase 8 |
| USP46 | ubiquitin specific peptidase 46 |
| ZBTB1 | zinc finger and BTB domain containing 1 |
| ZNF862 | zinc finger protein 862 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| ALS2CL | ALS2 C-terminal like |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ARRB1 | arrestin, beta 1 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C11ORF21 | chromosome 11 open reading frame 21 |
| CCDC186 | coiled-coil domain containing 186 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CD180 | CD180 molecule |
| CD37 | CD37 molecule |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHMP6 | charged multivesicular body protein 6 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| COL15A1 | collagen, type XV, alpha 1 |
| COQ6 | coenzyme Q6 monooxygenase |
| CPTP | ceramide-1-phosphate transfer protein |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DDX43 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 |
| DENND2D | DENN/MADD domain containing 2D |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DPY19L2P2 | DPY19L2 pseudogene 2 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| FAM188A | family with sequence similarity 188, member A |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FKBP5 | FK506 binding protein 5 |
| FLT3 | fms-related tyrosine kinase 3 |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GPR27 | G protein-coupled receptor 27 |
| GTF2I | general transcription factor IIi |
| HDAC9 | histone deacetylase 9 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOPX | HOP homeobox |
| HSPBP1 | HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MDM4 | MDM4, p53 regulator |
| MED9 | mediator complex subunit 9 |
| MEST | mesoderm specific transcript |
| METTL16 | methyltransferase like 16 |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MPI | mannose phosphate isomerase |
| MYH15 | myosin, heavy chain 15 |
| NOL10 | nucleolar protein 10 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| PADI2 | peptidyl arginine deiminase, type II |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma |
| POMZP3 | POM121 and ZP3 fusion |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
| PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E |
| PRR14L | proline rich 14-like |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 |
| PYGB | phosphorylase, glycogen; brain |
| RAB13 | RAB13, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) |
| RNF122 | ring finger protein 122 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SHARPIN | SHANK-associated RH domain interactor |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SPIDR | scaffolding protein involved in DNA repair |
| SREK1IP1 | SREK1-interacting protein 1 |
| SSBP3 | single stranded DNA binding protein 3 |
| ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| STEAP3 | STEAP family member 3, metalloreductase |
| STX1A | syntaxin 1A (brain) |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| SYCP2 | synaptonemal complex protein 2 |
| SYNC | syncoilin, intermediate filament protein |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| THAP10 | THAP domain containing 10 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZKSCAN8 | zinc finger with KRAB and SCAN domains 8 |
| ZNF155 | zinc finger protein 155 |
| ZNF428 | zinc finger protein 428 |
| ZNF529 | zinc finger protein 529 |
| ZSCAN16 | zinc finger and SCAN domain containing 16 |
