| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the etilefrine-4415 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOX2 | acyl-CoA oxidase 2, branched chain |
| ADAM12 | ADAM metallopeptidase domain 12 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| APAF1 | apoptotic peptidase activating factor 1 |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| ATP10B | ATPase, class V, type 10B |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| BMP1 | bone morphogenetic protein 1 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| CALCR | calcitonin receptor |
| CCDC40 | coiled-coil domain containing 40 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CTNS | cystinosin, lysosomal cystine transporter |
| CYP4A22 | cytochrome P450, family 4, subfamily A, polypeptide 22 |
| DES | desmin |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DOCK9 | dedicator of cytokinesis 9 |
| DOPEY2 | dopey family member 2 |
| EFNB1 | ephrin-B1 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) |
| ELN | elastin |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FAM13A | family with sequence similarity 13, member A |
| FGFR1 | fibroblast growth factor receptor 1 |
| FRMD1 | FERM domain containing 1 |
| FSTL1 | follistatin-like 1 |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GP2 | glycoprotein 2 (zymogen granule membrane) |
| GPR182 | G protein-coupled receptor 182 |
| GPR85 | G protein-coupled receptor 85 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HAO2 | hydroxyacid oxidase 2 (long chain) |
| HAP1 | huntingtin-associated protein 1 |
| HFE | hemochromatosis |
| HIST1H2BB | histone cluster 1, H2bb |
| HRH1 | histamine receptor H1 |
| HYAL1 | hyaluronoglucosaminidase 1 |
| IFNA2 | interferon, alpha 2 |
| IMPG2 | interphotoreceptor matrix proteoglycan 2 |
| INE1 | inactivation escape 1 (non-protein coding) |
| IQCK | IQ motif containing K |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KHSRP | KH-type splicing regulatory protein |
| KIAA1462 | KIAA1462 |
| KIF13B | kinesin family member 13B |
| LOC390998 | ribosomal protein L10 pseudogene |
| MAL | mal, T-cell differentiation protein |
| MALL | mal, T-cell differentiation protein-like |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MMP13 | matrix metallopeptidase 13 |
| MPL | MPL proto-oncogene, thrombopoietin receptor |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MUC3B | mucin 3B, cell surface associated |
| MVB12B | multivesicular body subunit 12B |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPPA | natriuretic peptide A |
| PCDH1 | protocadherin 1 |
| PDHA2 | pyruvate dehydrogenase (lipoamide) alpha 2 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) |
| PHF1 | PHD finger protein 1 |
| PKP2 | plakophilin 2 |
| PLCB2 | phospholipase C, beta 2 |
| PLSCR2 | phospholipid scramblase 2 |
| POU5F1B | POU class 5 homeobox 1B |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| RASL11B | RAS-like, family 11, member B |
| RBP4 | retinol binding protein 4, plasma |
| RGS6 | regulator of G-protein signaling 6 |
| RTN1 | reticulon 1 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SCARF1 | scavenger receptor class F, member 1 |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SNTG1 | syntrophin, gamma 1 |
| SPAM1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa |
| STS | steroid sulfatase (microsomal), isozyme S |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa |
| TAPBPL | TAP binding protein-like |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TRIM3 | tripartite motif containing 3 |
| TSKS | testis-specific serine kinase substrate |
| TTC38 | tetratricopeptide repeat domain 38 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| TUBA3C | tubulin, alpha 3c |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| WFDC8 | WAP four-disulfide core domain 8 |
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ACTL8 | actin-like 8 |
| AFAP1 | actin filament associated protein 1 |
| AMH | anti-Mullerian hormone |
| AOC2 | amine oxidase, copper containing 2 (retina-specific) |
| ARC | activity-regulated cytoskeleton-associated protein |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CBR3 | carbonyl reductase 3 |
| CBX8 | chromobox homolog 8 |
| CCDC121 | coiled-coil domain containing 121 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDHR2 | cadherin-related family member 2 |
| CDK6 | cyclin-dependent kinase 6 |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CES3 | carboxylesterase 3 |
| CFAP45 | cilia and flagella associated protein 45 |
| CPNE7 | copine VII |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CRY2 | cryptochrome circadian clock 2 |
| CSF1R | colony stimulating factor 1 receptor |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DGKQ | diacylglycerol kinase, theta 110kDa |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| EXOC6B | exocyst complex component 6B |
| FAM120C | family with sequence similarity 120C |
| FAM188A | family with sequence similarity 188, member A |
| FGL1 | fibrinogen-like 1 |
| FLJ21369 | uncharacterized protein FLJ21369 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GATA4 | GATA binding protein 4 |
| GPC3 | glypican 3 |
| GPR3 | G protein-coupled receptor 3 |
| HIST1H3E | histone cluster 1, H3e |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| HSF1 | heat shock transcription factor 1 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFT54 | intraflagellar transport 54 |
| IL17RA | interleukin 17 receptor A |
| IL2 | interleukin 2 |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| IRF9 | interferon regulatory factor 9 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIAA0754 | KIAA0754 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LOC729164 | hCG1732469 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MEGF6 | multiple EGF-like-domains 6 |
| MSI1 | musashi RNA-binding protein 1 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming |
| MX2 | MX dynamin-like GTPase 2 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| NEUROD4 | neuronal differentiation 4 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NME5 | NME/NM23 family member 5 |
| NPY4R | neuropeptide Y receptor Y4 |
| PDE12 | phosphodiesterase 12 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PDE8B | phosphodiesterase 8B |
| PICK1 | protein interacting with PRKCA 1 |
| PLXNB3 | plexin B3 |
| POLL | polymerase (DNA directed), lambda |
| PRAMEF11 | PRAME family member 11 |
| PRKCE | protein kinase C, epsilon |
| QSER1 | glutamine and serine rich 1 |
| RAB40C | RAB40C, member RAS oncogene family |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RGS20 | regulator of G-protein signaling 20 |
| RNF39 | ring finger protein 39 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| RORC | RAR-related orphan receptor C |
| RPH3A | rabphilin 3A |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| TPSG1 | tryptase gamma 1 |
| TRIM21 | tripartite motif containing 21 |
| TWISTNB | TWIST neighbor |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| VLDLR | very low density lipoprotein receptor |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF324 | zinc finger protein 324 |
| ZNF532 | zinc finger protein 532 |
| ZNF750 | zinc finger protein 750 |
| ZNF804A | zinc finger protein 804A |
| ZNF862 | zinc finger protein 862 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
